| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| CPSF1 | CPSF2 | ENSPPYP00000021278 | ENSPPYP00000023779 | CPSF1 isoform 3. | Cleavage and polyadenylation specificity factor subunit 2. | 0.996 |
| CPSF1 | CSTF1 | ENSPPYP00000021278 | ENSPPYP00000024472 | CPSF1 isoform 3. | Cleavage stimulation factor subunit 1; One of the multiple factors required for polyadenylation and 3'-end cleavage of mammalian pre-mRNAs (By similarity). May be responsible for the interaction of CSTF with other factors to form a stable complex on the pre-mRNA (By similarity). | 0.918 |
| CPSF1 | CSTF3 | ENSPPYP00000021278 | ENSPPYP00000003876 | CPSF1 isoform 3. | Cleavage stimulation factor subunit 3; One of the multiple factors required for polyadenylation and 3'-end cleavage of mammalian pre-mRNAs. | 0.994 |
| CPSF1 | NUDT21 | ENSPPYP00000021278 | ENSPPYP00000008319 | CPSF1 isoform 3. | Cleavage and polyadenylation specificity factor subunit 5; Component of the cleavage factor Im (CFIm) complex that functions as an activator of the pre-mRNA 3'-end cleavage and polyadenylation processing required for the maturation of pre-mRNA into functional mRNAs. CFIm contributes to the recruitment of multiprotein complexes on specific sequences on the pre-mRNA 3'-end, so called cleavage and polyadenylation signals (pA signals). Most pre-mRNAs contain multiple pA signals, resulting in alternative cleavage and polyadenylation (APA) producing mRNAs with variable 3'-end formation. The [...] | 0.924 |
| CPSF1 | YTHDC2 | ENSPPYP00000021278 | ENSPPYP00000017549 | CPSF1 isoform 3. | 3'-5' RNA helicase YTHDC2; 3'-5' RNA helicase that plays a key role in the male and female germline by promoting transition from mitotic to meiotic divisions in stem cells. Specifically recognizes and binds N6- methyladenosine (m6A)-containing RNAs, a modification present at internal sites of mRNAs and some non-coding RNAs that plays a role in the efficiency of RNA processing and stability. Essential for ensuring a successful progression of the meiotic program in the germline by regulating the level of m6A-containing RNAs. Acts by binding and promoting degradation of m6A-containing mRN [...] | 0.796 |
| CPSF2 | CPSF1 | ENSPPYP00000023779 | ENSPPYP00000021278 | Cleavage and polyadenylation specificity factor subunit 2. | CPSF1 isoform 3. | 0.996 |
| CPSF2 | CSTF1 | ENSPPYP00000023779 | ENSPPYP00000024472 | Cleavage and polyadenylation specificity factor subunit 2. | Cleavage stimulation factor subunit 1; One of the multiple factors required for polyadenylation and 3'-end cleavage of mammalian pre-mRNAs (By similarity). May be responsible for the interaction of CSTF with other factors to form a stable complex on the pre-mRNA (By similarity). | 0.979 |
| CPSF2 | CSTF3 | ENSPPYP00000023779 | ENSPPYP00000003876 | Cleavage and polyadenylation specificity factor subunit 2. | Cleavage stimulation factor subunit 3; One of the multiple factors required for polyadenylation and 3'-end cleavage of mammalian pre-mRNAs. | 0.881 |
| CPSF2 | NUDT21 | ENSPPYP00000023779 | ENSPPYP00000008319 | Cleavage and polyadenylation specificity factor subunit 2. | Cleavage and polyadenylation specificity factor subunit 5; Component of the cleavage factor Im (CFIm) complex that functions as an activator of the pre-mRNA 3'-end cleavage and polyadenylation processing required for the maturation of pre-mRNA into functional mRNAs. CFIm contributes to the recruitment of multiprotein complexes on specific sequences on the pre-mRNA 3'-end, so called cleavage and polyadenylation signals (pA signals). Most pre-mRNAs contain multiple pA signals, resulting in alternative cleavage and polyadenylation (APA) producing mRNAs with variable 3'-end formation. The [...] | 0.925 |
| CPSF2 | YTHDC2 | ENSPPYP00000023779 | ENSPPYP00000017549 | Cleavage and polyadenylation specificity factor subunit 2. | 3'-5' RNA helicase YTHDC2; 3'-5' RNA helicase that plays a key role in the male and female germline by promoting transition from mitotic to meiotic divisions in stem cells. Specifically recognizes and binds N6- methyladenosine (m6A)-containing RNAs, a modification present at internal sites of mRNAs and some non-coding RNAs that plays a role in the efficiency of RNA processing and stability. Essential for ensuring a successful progression of the meiotic program in the germline by regulating the level of m6A-containing RNAs. Acts by binding and promoting degradation of m6A-containing mRN [...] | 0.816 |
| CSTF1 | CPSF1 | ENSPPYP00000024472 | ENSPPYP00000021278 | Cleavage stimulation factor subunit 1; One of the multiple factors required for polyadenylation and 3'-end cleavage of mammalian pre-mRNAs (By similarity). May be responsible for the interaction of CSTF with other factors to form a stable complex on the pre-mRNA (By similarity). | CPSF1 isoform 3. | 0.918 |
| CSTF1 | CPSF2 | ENSPPYP00000024472 | ENSPPYP00000023779 | Cleavage stimulation factor subunit 1; One of the multiple factors required for polyadenylation and 3'-end cleavage of mammalian pre-mRNAs (By similarity). May be responsible for the interaction of CSTF with other factors to form a stable complex on the pre-mRNA (By similarity). | Cleavage and polyadenylation specificity factor subunit 2. | 0.979 |
| CSTF1 | CSTF3 | ENSPPYP00000024472 | ENSPPYP00000003876 | Cleavage stimulation factor subunit 1; One of the multiple factors required for polyadenylation and 3'-end cleavage of mammalian pre-mRNAs (By similarity). May be responsible for the interaction of CSTF with other factors to form a stable complex on the pre-mRNA (By similarity). | Cleavage stimulation factor subunit 3; One of the multiple factors required for polyadenylation and 3'-end cleavage of mammalian pre-mRNAs. | 0.999 |
| CSTF1 | NUDT21 | ENSPPYP00000024472 | ENSPPYP00000008319 | Cleavage stimulation factor subunit 1; One of the multiple factors required for polyadenylation and 3'-end cleavage of mammalian pre-mRNAs (By similarity). May be responsible for the interaction of CSTF with other factors to form a stable complex on the pre-mRNA (By similarity). | Cleavage and polyadenylation specificity factor subunit 5; Component of the cleavage factor Im (CFIm) complex that functions as an activator of the pre-mRNA 3'-end cleavage and polyadenylation processing required for the maturation of pre-mRNA into functional mRNAs. CFIm contributes to the recruitment of multiprotein complexes on specific sequences on the pre-mRNA 3'-end, so called cleavage and polyadenylation signals (pA signals). Most pre-mRNAs contain multiple pA signals, resulting in alternative cleavage and polyadenylation (APA) producing mRNAs with variable 3'-end formation. The [...] | 0.860 |
| CSTF1 | YTHDC2 | ENSPPYP00000024472 | ENSPPYP00000017549 | Cleavage stimulation factor subunit 1; One of the multiple factors required for polyadenylation and 3'-end cleavage of mammalian pre-mRNAs (By similarity). May be responsible for the interaction of CSTF with other factors to form a stable complex on the pre-mRNA (By similarity). | 3'-5' RNA helicase YTHDC2; 3'-5' RNA helicase that plays a key role in the male and female germline by promoting transition from mitotic to meiotic divisions in stem cells. Specifically recognizes and binds N6- methyladenosine (m6A)-containing RNAs, a modification present at internal sites of mRNAs and some non-coding RNAs that plays a role in the efficiency of RNA processing and stability. Essential for ensuring a successful progression of the meiotic program in the germline by regulating the level of m6A-containing RNAs. Acts by binding and promoting degradation of m6A-containing mRN [...] | 0.803 |
| CSTF3 | CPSF1 | ENSPPYP00000003876 | ENSPPYP00000021278 | Cleavage stimulation factor subunit 3; One of the multiple factors required for polyadenylation and 3'-end cleavage of mammalian pre-mRNAs. | CPSF1 isoform 3. | 0.994 |
| CSTF3 | CPSF2 | ENSPPYP00000003876 | ENSPPYP00000023779 | Cleavage stimulation factor subunit 3; One of the multiple factors required for polyadenylation and 3'-end cleavage of mammalian pre-mRNAs. | Cleavage and polyadenylation specificity factor subunit 2. | 0.881 |
| CSTF3 | CSTF1 | ENSPPYP00000003876 | ENSPPYP00000024472 | Cleavage stimulation factor subunit 3; One of the multiple factors required for polyadenylation and 3'-end cleavage of mammalian pre-mRNAs. | Cleavage stimulation factor subunit 1; One of the multiple factors required for polyadenylation and 3'-end cleavage of mammalian pre-mRNAs (By similarity). May be responsible for the interaction of CSTF with other factors to form a stable complex on the pre-mRNA (By similarity). | 0.999 |
| CSTF3 | NUDT21 | ENSPPYP00000003876 | ENSPPYP00000008319 | Cleavage stimulation factor subunit 3; One of the multiple factors required for polyadenylation and 3'-end cleavage of mammalian pre-mRNAs. | Cleavage and polyadenylation specificity factor subunit 5; Component of the cleavage factor Im (CFIm) complex that functions as an activator of the pre-mRNA 3'-end cleavage and polyadenylation processing required for the maturation of pre-mRNA into functional mRNAs. CFIm contributes to the recruitment of multiprotein complexes on specific sequences on the pre-mRNA 3'-end, so called cleavage and polyadenylation signals (pA signals). Most pre-mRNAs contain multiple pA signals, resulting in alternative cleavage and polyadenylation (APA) producing mRNAs with variable 3'-end formation. The [...] | 0.828 |
| CSTF3 | YTHDC2 | ENSPPYP00000003876 | ENSPPYP00000017549 | Cleavage stimulation factor subunit 3; One of the multiple factors required for polyadenylation and 3'-end cleavage of mammalian pre-mRNAs. | 3'-5' RNA helicase YTHDC2; 3'-5' RNA helicase that plays a key role in the male and female germline by promoting transition from mitotic to meiotic divisions in stem cells. Specifically recognizes and binds N6- methyladenosine (m6A)-containing RNAs, a modification present at internal sites of mRNAs and some non-coding RNAs that plays a role in the efficiency of RNA processing and stability. Essential for ensuring a successful progression of the meiotic program in the germline by regulating the level of m6A-containing RNAs. Acts by binding and promoting degradation of m6A-containing mRN [...] | 0.799 |