STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SEMA6ASEMA6A isoform 1; Belongs to the semaphorin family. (1030 aa)    
Predicted Functional Partners:
PLXNA4
PLXNA4 isoform 2.
    
0.989
PLXNA2
PLXNA2 isoform 1.
    
0.976
SEMA6C
SEMA6C isoform 1; Belongs to the semaphorin family.
     
0.903
PLXNA3
PLXNA3 isoform 1.
    
 0.843
PLXNA1
PLXNA1 isoform 1.
    
 0.838
NRP1
Neuropilin; Belongs to the neuropilin family.
    
 0.824
PLXND1
PLXND1 isoform 1.
    
 0.727
PLXNC1
PLXNC1 isoform 1.
    
 0.726
MST1R
MST1R isoform 1.
    
 0.715
EVL
Ena/VASP-like protein; Ena/VASP proteins are actin-associated proteins involved in a range of processes dependent on cytoskeleton remodeling and cell polarity such as axon guidance and lamellipodial and filopodial dynamics in migrating cells. EVL enhances actin nucleation and polymerization (By similarity).
    
 
 0.698
Your Current Organism:
Pongo abelii
NCBI taxonomy Id: 9601
Other names: Orang-utan, Orangutan, P. abelii, Pongo pygmaeus abeli, Pongo pygmaeus abelii, Sumatran orangutan, orang utan
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.