| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| DDX41 | IFI16 | ENSPPYP00000018013 | ENSPPYP00000000774 | DDX41 isoform 1. | Gamma-interferon-inducible protein 16; Binds double-stranded DNA. Binds preferentially to supercoiled DNA and cruciform DNA structures. Seems to be involved in transcriptional regulation. May function as a transcriptional repressor. Could have a role in the regulation of hematopoietic differentiation through activation of unknown target genes. Controls cellular proliferation by modulating the functions of cell cycle regulatory factors including p53/TP53 and the retinoblastoma protein. May be involved in TP53-mediated transcriptional activation by enhancing TP53 sequence-specific DNA bi [...] | 0.643 |
| DDX41 | IKBKE | ENSPPYP00000018013 | ENSPPYP00000000308 | DDX41 isoform 1. | Inhibitor of nuclear factor kappa B kinase subunit epsilon. | 0.492 |
| DDX41 | IRF3 | ENSPPYP00000018013 | ENSPPYP00000011485 | DDX41 isoform 1. | IRF3 isoform 6. | 0.755 |
| DDX41 | STING1 | ENSPPYP00000018013 | ENSPPYP00000017715 | DDX41 isoform 1. | Transmembrane protein 173. | 0.977 |
| DDX41 | TBK1 | ENSPPYP00000018013 | ENSPPYP00000005386 | DDX41 isoform 1. | TANK binding kinase 1. | 0.630 |
| DDX41 | TRIM32 | ENSPPYP00000018013 | ENSPPYP00000021906 | DDX41 isoform 1. | Tripartite motif containing 32. | 0.460 |
| DDX41 | TRIM56 | ENSPPYP00000018013 | ENSPPYP00000019548 | DDX41 isoform 1. | TRIM56 isoform 1. | 0.486 |
| IFI16 | DDX41 | ENSPPYP00000000774 | ENSPPYP00000018013 | Gamma-interferon-inducible protein 16; Binds double-stranded DNA. Binds preferentially to supercoiled DNA and cruciform DNA structures. Seems to be involved in transcriptional regulation. May function as a transcriptional repressor. Could have a role in the regulation of hematopoietic differentiation through activation of unknown target genes. Controls cellular proliferation by modulating the functions of cell cycle regulatory factors including p53/TP53 and the retinoblastoma protein. May be involved in TP53-mediated transcriptional activation by enhancing TP53 sequence-specific DNA bi [...] | DDX41 isoform 1. | 0.643 |
| IFI16 | IRF3 | ENSPPYP00000000774 | ENSPPYP00000011485 | Gamma-interferon-inducible protein 16; Binds double-stranded DNA. Binds preferentially to supercoiled DNA and cruciform DNA structures. Seems to be involved in transcriptional regulation. May function as a transcriptional repressor. Could have a role in the regulation of hematopoietic differentiation through activation of unknown target genes. Controls cellular proliferation by modulating the functions of cell cycle regulatory factors including p53/TP53 and the retinoblastoma protein. May be involved in TP53-mediated transcriptional activation by enhancing TP53 sequence-specific DNA bi [...] | IRF3 isoform 6. | 0.537 |
| IFI16 | STING1 | ENSPPYP00000000774 | ENSPPYP00000017715 | Gamma-interferon-inducible protein 16; Binds double-stranded DNA. Binds preferentially to supercoiled DNA and cruciform DNA structures. Seems to be involved in transcriptional regulation. May function as a transcriptional repressor. Could have a role in the regulation of hematopoietic differentiation through activation of unknown target genes. Controls cellular proliferation by modulating the functions of cell cycle regulatory factors including p53/TP53 and the retinoblastoma protein. May be involved in TP53-mediated transcriptional activation by enhancing TP53 sequence-specific DNA bi [...] | Transmembrane protein 173. | 0.988 |
| IFI16 | TBK1 | ENSPPYP00000000774 | ENSPPYP00000005386 | Gamma-interferon-inducible protein 16; Binds double-stranded DNA. Binds preferentially to supercoiled DNA and cruciform DNA structures. Seems to be involved in transcriptional regulation. May function as a transcriptional repressor. Could have a role in the regulation of hematopoietic differentiation through activation of unknown target genes. Controls cellular proliferation by modulating the functions of cell cycle regulatory factors including p53/TP53 and the retinoblastoma protein. May be involved in TP53-mediated transcriptional activation by enhancing TP53 sequence-specific DNA bi [...] | TANK binding kinase 1. | 0.520 |
| IKBKE | DDX41 | ENSPPYP00000000308 | ENSPPYP00000018013 | Inhibitor of nuclear factor kappa B kinase subunit epsilon. | DDX41 isoform 1. | 0.492 |
| IKBKE | IRF3 | ENSPPYP00000000308 | ENSPPYP00000011485 | Inhibitor of nuclear factor kappa B kinase subunit epsilon. | IRF3 isoform 6. | 0.999 |
| IKBKE | MAVS | ENSPPYP00000000308 | ENSPPYP00000012072 | Inhibitor of nuclear factor kappa B kinase subunit epsilon. | MAVS isoform 2. | 0.973 |
| IKBKE | STING1 | ENSPPYP00000000308 | ENSPPYP00000017715 | Inhibitor of nuclear factor kappa B kinase subunit epsilon. | Transmembrane protein 173. | 0.995 |
| IKBKE | TBK1 | ENSPPYP00000000308 | ENSPPYP00000005386 | Inhibitor of nuclear factor kappa B kinase subunit epsilon. | TANK binding kinase 1. | 0.999 |
| IKBKE | TRAF3 | ENSPPYP00000000308 | ENSPPYP00000007003 | Inhibitor of nuclear factor kappa B kinase subunit epsilon. | TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. | 0.997 |
| IRF3 | DDX41 | ENSPPYP00000011485 | ENSPPYP00000018013 | IRF3 isoform 6. | DDX41 isoform 1. | 0.755 |
| IRF3 | IFI16 | ENSPPYP00000011485 | ENSPPYP00000000774 | IRF3 isoform 6. | Gamma-interferon-inducible protein 16; Binds double-stranded DNA. Binds preferentially to supercoiled DNA and cruciform DNA structures. Seems to be involved in transcriptional regulation. May function as a transcriptional repressor. Could have a role in the regulation of hematopoietic differentiation through activation of unknown target genes. Controls cellular proliferation by modulating the functions of cell cycle regulatory factors including p53/TP53 and the retinoblastoma protein. May be involved in TP53-mediated transcriptional activation by enhancing TP53 sequence-specific DNA bi [...] | 0.537 |
| IRF3 | IKBKE | ENSPPYP00000011485 | ENSPPYP00000000308 | IRF3 isoform 6. | Inhibitor of nuclear factor kappa B kinase subunit epsilon. | 0.999 |
