Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
HTR45-hydroxytryptamine receptor 4; Belongs to the G-protein coupled receptor 1 family. (387 aa)    
Predicted Functional Partners:
GNAS
GNAS isoform 2.
    
 0.939
HTR6
HTR6 isoform 1; Belongs to the G-protein coupled receptor 1 family.
     
0.930
HTR7
HTR7 isoform 3; Belongs to the G-protein coupled receptor 1 family.
     
0.925
GNAL
GNAL isoform 3.
    
 0.765
GIP
GIP isoform 1.
     
 0.713
POMC
POMC isoform 1.
   
 0.706
FSHB
Follicle stimulating hormone beta subunit.
   
 
 0.704
ADCYAP1
Adenylate cyclase activating polypeptide 1.
    
 0.687
GPHB5
Glycoprotein hormone subunit beta 5.
   
 
  0.686
TSHB
Thyroid stimulating hormone subunit beta.
   
 
 0.684
Your Current Organism:
Pongo abelii
NCBI taxonomy Id: 9601
Other names: Orang-utan, Orangutan, P. abelii, Pongo pygmaeus abeli, Pongo pygmaeus abelii, Sumatran orangutan, orang utan
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