| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ANAPC1 | ANAPC10 | ENSPPYP00000013557 | ENSPPYP00000016864 | ANAPC1 isoform 2. | Anaphase-promoting complex subunit 10; Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin-protein ligase complex that controls progression through mitosis and the G1 phase of the cell cycle. | 0.998 |
| ANAPC1 | ANAPC2 | ENSPPYP00000013557 | ENSPPYP00000022215 | ANAPC1 isoform 2. | Anaphase promoting complex subunit 2; Belongs to the cullin family. | 0.998 |
| ANAPC1 | CDC20 | ENSPPYP00000013557 | ENSPPYP00000001678 | ANAPC1 isoform 2. | Cell division cycle 20. | 0.994 |
| ANAPC1 | CDC20B | ENSPPYP00000013557 | ENSPPYP00000017282 | ANAPC1 isoform 2. | CDC20B isoform 4. | 0.945 |
| ANAPC1 | CDC26 | ENSPPYP00000013557 | ENSPPYP00000021868 | ANAPC1 isoform 2. | Anaphase-promoting complex subunit CDC26; Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. The APC/C complex acts by mediating ubiquitination and subsequent degradation of target proteins: it mainly mediates the formation of 'Lys-11'-linked polyubiquitin chains and, to a lower extent, the formation of 'Lys-48'- and 'Lys-63'-linked polyubiquitin chains. May recruit the E2 ubiquitin-conjugating enzymes to the complex (By similarity); Belongs to the CDC26 [...] | 0.997 |
| ANAPC1 | CDC27 | ENSPPYP00000013557 | ENSPPYP00000010040 | ANAPC1 isoform 2. | CDC27 isoform 1. | 0.998 |
| ANAPC1 | CDK1 | ENSPPYP00000013557 | ENSPPYP00000002808 | ANAPC1 isoform 2. | Cyclin-dependent kinase 1; Plays a key role in the control of the eukaryotic cell cycle by modulating the centrosome cycle as well as mitotic onset; promotes G2-M transition, and regulates G1 progress and G1-S transition via association with multiple interphase cyclins. Required in higher cells for entry into S-phase and mitosis. Phosphorylates PARVA/actopaxin, APC, AMPH, APC, BARD1, Bcl-xL/BCL2L1, BRCA2, CALD1, CASP8, CDC7, CDC20, CDC25A, CDC25C, CC2D1A, CENPA, CSNK2 proteins/CKII, FZR1/CDH1, CDK7, CEBPB, CHAMP1, DMD/dystrophin, EEF1 proteins/EF-1, EZH2, KIF11/EG5, EGFR, FANCG, FOS, G [...] | 0.901 |
| ANAPC1 | ESPL1 | ENSPPYP00000013557 | ENSPPYP00000005218 | ANAPC1 isoform 2. | ESPL1 isoform 1. | 0.735 |
| ANAPC1 | FZR1 | ENSPPYP00000013557 | ENSPPYP00000010515 | ANAPC1 isoform 2. | FZR1 isoform 4. | 0.985 |
| ANAPC1 | PTTG1 | ENSPPYP00000013557 | ENSPPYP00000017915 | ANAPC1 isoform 2. | PTTG1 regulator of sister chromatid separation, securin. | 0.974 |
| ANAPC10 | ANAPC1 | ENSPPYP00000016864 | ENSPPYP00000013557 | Anaphase-promoting complex subunit 10; Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin-protein ligase complex that controls progression through mitosis and the G1 phase of the cell cycle. | ANAPC1 isoform 2. | 0.998 |
| ANAPC10 | ANAPC2 | ENSPPYP00000016864 | ENSPPYP00000022215 | Anaphase-promoting complex subunit 10; Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin-protein ligase complex that controls progression through mitosis and the G1 phase of the cell cycle. | Anaphase promoting complex subunit 2; Belongs to the cullin family. | 0.998 |
| ANAPC10 | CDC20 | ENSPPYP00000016864 | ENSPPYP00000001678 | Anaphase-promoting complex subunit 10; Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin-protein ligase complex that controls progression through mitosis and the G1 phase of the cell cycle. | Cell division cycle 20. | 0.993 |
| ANAPC10 | CDC20B | ENSPPYP00000016864 | ENSPPYP00000017282 | Anaphase-promoting complex subunit 10; Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin-protein ligase complex that controls progression through mitosis and the G1 phase of the cell cycle. | CDC20B isoform 4. | 0.935 |
| ANAPC10 | CDC26 | ENSPPYP00000016864 | ENSPPYP00000021868 | Anaphase-promoting complex subunit 10; Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin-protein ligase complex that controls progression through mitosis and the G1 phase of the cell cycle. | Anaphase-promoting complex subunit CDC26; Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. The APC/C complex acts by mediating ubiquitination and subsequent degradation of target proteins: it mainly mediates the formation of 'Lys-11'-linked polyubiquitin chains and, to a lower extent, the formation of 'Lys-48'- and 'Lys-63'-linked polyubiquitin chains. May recruit the E2 ubiquitin-conjugating enzymes to the complex (By similarity); Belongs to the CDC26 [...] | 0.998 |
| ANAPC10 | CDC27 | ENSPPYP00000016864 | ENSPPYP00000010040 | Anaphase-promoting complex subunit 10; Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin-protein ligase complex that controls progression through mitosis and the G1 phase of the cell cycle. | CDC27 isoform 1. | 0.998 |
| ANAPC10 | CDK1 | ENSPPYP00000016864 | ENSPPYP00000002808 | Anaphase-promoting complex subunit 10; Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin-protein ligase complex that controls progression through mitosis and the G1 phase of the cell cycle. | Cyclin-dependent kinase 1; Plays a key role in the control of the eukaryotic cell cycle by modulating the centrosome cycle as well as mitotic onset; promotes G2-M transition, and regulates G1 progress and G1-S transition via association with multiple interphase cyclins. Required in higher cells for entry into S-phase and mitosis. Phosphorylates PARVA/actopaxin, APC, AMPH, APC, BARD1, Bcl-xL/BCL2L1, BRCA2, CALD1, CASP8, CDC7, CDC20, CDC25A, CDC25C, CC2D1A, CENPA, CSNK2 proteins/CKII, FZR1/CDH1, CDK7, CEBPB, CHAMP1, DMD/dystrophin, EEF1 proteins/EF-1, EZH2, KIF11/EG5, EGFR, FANCG, FOS, G [...] | 0.820 |
| ANAPC10 | ESPL1 | ENSPPYP00000016864 | ENSPPYP00000005218 | Anaphase-promoting complex subunit 10; Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin-protein ligase complex that controls progression through mitosis and the G1 phase of the cell cycle. | ESPL1 isoform 1. | 0.905 |
| ANAPC10 | FZR1 | ENSPPYP00000016864 | ENSPPYP00000010515 | Anaphase-promoting complex subunit 10; Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin-protein ligase complex that controls progression through mitosis and the G1 phase of the cell cycle. | FZR1 isoform 4. | 0.908 |
| ANAPC10 | PTTG1 | ENSPPYP00000016864 | ENSPPYP00000017915 | Anaphase-promoting complex subunit 10; Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin-protein ligase complex that controls progression through mitosis and the G1 phase of the cell cycle. | PTTG1 regulator of sister chromatid separation, securin. | 0.975 |
