| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ADAM10 | TSPAN17 | ENSPPYP00000007386 | ENSPPYP00000017993 | ADAM10 isoform 1. | Tetraspanin. | 0.653 |
| CR201_G0042455 | TSPAN17 | ENSPPYP00000018322 | ENSPPYP00000017993 | GABBR1 isoform 2. | Tetraspanin. | 0.492 |
| DHX35 | TBCEL | ENSPPYP00000012292 | ENSPPYP00000004556 | Probable ATP-dependent RNA helicase DHX35; May be involved in pre-mRNA splicing. | TBCEL isoform 1. | 0.656 |
| DHX35 | TSPAN17 | ENSPPYP00000012292 | ENSPPYP00000017993 | Probable ATP-dependent RNA helicase DHX35; May be involved in pre-mRNA splicing. | Tetraspanin. | 0.527 |
| SCG5 | TSPAN17 | ENSPPYP00000007139 | ENSPPYP00000017993 | Secretogranin V. | Tetraspanin. | 0.485 |
| TBCEL | DHX35 | ENSPPYP00000004556 | ENSPPYP00000012292 | TBCEL isoform 1. | Probable ATP-dependent RNA helicase DHX35; May be involved in pre-mRNA splicing. | 0.656 |
| TBCEL | TSPAN17 | ENSPPYP00000004556 | ENSPPYP00000017993 | TBCEL isoform 1. | Tetraspanin. | 0.515 |
| TSPAN1 | TSPAN17 | ENSPPYP00000001626 | ENSPPYP00000017993 | Tetraspanin-1. | Tetraspanin. | 0.469 |
| TSPAN1 | TSPAN31 | ENSPPYP00000001626 | ENSPPYP00000005359 | Tetraspanin-1. | Tetraspanin-31. | 0.487 |
| TSPAN12 | TSPAN17 | ENSPPYP00000020123 | ENSPPYP00000017993 | Tetraspanin-12; Regulator of cell surface receptor signal transduction. Plays a central role in retinal vascularization by regulating norrin (NDP) signal transduction. Acts in concert with norrin (NDP) to promote FZD4 multimerization and subsequent activation of FZD4, leading to promote accumulation of beta-catenin (CTNNB1) and stimulate LEF/TCF-mediated transcriptional programs. Suprisingly, it only activate the norrin (NDP)-dependent activation of FZD4, while it does not activate the Wnt- dependent activation of FZD4, suggesting the existence of a Wnt- independent signaling that also [...] | Tetraspanin. | 0.446 |
| TSPAN13 | TSPAN17 | ENSPPYP00000019910 | ENSPPYP00000017993 | TSPAN13 isoform 1; Belongs to the tetraspanin (TM4SF) family. | Tetraspanin. | 0.516 |
| TSPAN16 | TSPAN17 | ENSPPYP00000010738 | ENSPPYP00000017993 | Tetraspanin. | Tetraspanin. | 0.628 |
| TSPAN16 | TSPAN31 | ENSPPYP00000010738 | ENSPPYP00000005359 | Tetraspanin. | Tetraspanin-31. | 0.615 |
| TSPAN17 | ADAM10 | ENSPPYP00000017993 | ENSPPYP00000007386 | Tetraspanin. | ADAM10 isoform 1. | 0.653 |
| TSPAN17 | CR201_G0042455 | ENSPPYP00000017993 | ENSPPYP00000018322 | Tetraspanin. | GABBR1 isoform 2. | 0.492 |
| TSPAN17 | DHX35 | ENSPPYP00000017993 | ENSPPYP00000012292 | Tetraspanin. | Probable ATP-dependent RNA helicase DHX35; May be involved in pre-mRNA splicing. | 0.527 |
| TSPAN17 | SCG5 | ENSPPYP00000017993 | ENSPPYP00000007139 | Tetraspanin. | Secretogranin V. | 0.485 |
| TSPAN17 | TBCEL | ENSPPYP00000017993 | ENSPPYP00000004556 | Tetraspanin. | TBCEL isoform 1. | 0.515 |
| TSPAN17 | TSPAN1 | ENSPPYP00000017993 | ENSPPYP00000001626 | Tetraspanin. | Tetraspanin-1. | 0.469 |
| TSPAN17 | TSPAN12 | ENSPPYP00000017993 | ENSPPYP00000020123 | Tetraspanin. | Tetraspanin-12; Regulator of cell surface receptor signal transduction. Plays a central role in retinal vascularization by regulating norrin (NDP) signal transduction. Acts in concert with norrin (NDP) to promote FZD4 multimerization and subsequent activation of FZD4, leading to promote accumulation of beta-catenin (CTNNB1) and stimulate LEF/TCF-mediated transcriptional programs. Suprisingly, it only activate the norrin (NDP)-dependent activation of FZD4, while it does not activate the Wnt- dependent activation of FZD4, suggesting the existence of a Wnt- independent signaling that also [...] | 0.446 |
