DBN1 protein (Pongo abelii) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Current Organism:

Pongo abelii

NCBI taxonomy Id: 9601
Other names: Orang-utan, Orangutan, P. abelii, Pongo pygmaeus abeli, Pongo pygmaeus abelii, Sumatran orangutan, orang utan

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structured XML interaction data, according to the 'PSI-MI' data standard

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... protein annotations:

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ACTB	CAPZB	ENSPPYP00000019427	ENSPPYP00000002072	Actin, cytoplasmic 1, N-terminally processed; Actin is a highly conserved protein that polymerizes to produce filaments that form cross-linked networks in the cytoplasm of cells. Actin exists in both monomeric (G-actin) and polymeric (F-actin) forms, both forms playing key functions, such as cell motility and contraction. In addition to their role in the cytoplasmic cytoskeleton, G- and F-actin also localize in the nucleus, and regulate gene transcription and motility and repair of damaged DNA.	F-actin-capping protein subunit beta; F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments. Plays a role in the regulation of cell morphology and cytoskeletal organization (By similarity).	0.938
ACTB	DBN1	ENSPPYP00000019427	ENSPPYP00000018010	Actin, cytoplasmic 1, N-terminally processed; Actin is a highly conserved protein that polymerizes to produce filaments that form cross-linked networks in the cytoplasm of cells. Actin exists in both monomeric (G-actin) and polymeric (F-actin) forms, both forms playing key functions, such as cell motility and contraction. In addition to their role in the cytoplasmic cytoskeleton, G- and F-actin also localize in the nucleus, and regulate gene transcription and motility and repair of damaged DNA.	DBN1 isoform 4.	0.924
ACTB	GSN	ENSPPYP00000019427	ENSPPYP00000021923	Actin, cytoplasmic 1, N-terminally processed; Actin is a highly conserved protein that polymerizes to produce filaments that form cross-linked networks in the cytoplasm of cells. Actin exists in both monomeric (G-actin) and polymeric (F-actin) forms, both forms playing key functions, such as cell motility and contraction. In addition to their role in the cytoplasmic cytoskeleton, G- and F-actin also localize in the nucleus, and regulate gene transcription and motility and repair of damaged DNA.	GSN isoform 1.	0.813
ACTB	HIP1R	ENSPPYP00000019427	ENSPPYP00000005782	Actin, cytoplasmic 1, N-terminally processed; Actin is a highly conserved protein that polymerizes to produce filaments that form cross-linked networks in the cytoplasm of cells. Actin exists in both monomeric (G-actin) and polymeric (F-actin) forms, both forms playing key functions, such as cell motility and contraction. In addition to their role in the cytoplasmic cytoskeleton, G- and F-actin also localize in the nucleus, and regulate gene transcription and motility and repair of damaged DNA.	HIP1R isoform 1.	0.587
CAPG	DBN1	ENSPPYP00000013640	ENSPPYP00000018010	Capping actin protein, gelsolin like.	DBN1 isoform 4.	0.697
CAPG	TMOD2	ENSPPYP00000013640	ENSPPYP00000007342	Capping actin protein, gelsolin like.	TMOD2 isoform 1.	0.505
CAPZB	ACTB	ENSPPYP00000002072	ENSPPYP00000019427	F-actin-capping protein subunit beta; F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments. Plays a role in the regulation of cell morphology and cytoskeletal organization (By similarity).	Actin, cytoplasmic 1, N-terminally processed; Actin is a highly conserved protein that polymerizes to produce filaments that form cross-linked networks in the cytoplasm of cells. Actin exists in both monomeric (G-actin) and polymeric (F-actin) forms, both forms playing key functions, such as cell motility and contraction. In addition to their role in the cytoplasmic cytoskeleton, G- and F-actin also localize in the nucleus, and regulate gene transcription and motility and repair of damaged DNA.	0.938
CAPZB	DBN1	ENSPPYP00000002072	ENSPPYP00000018010	F-actin-capping protein subunit beta; F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments. Plays a role in the regulation of cell morphology and cytoskeletal organization (By similarity).	DBN1 isoform 4.	0.742
DBN1	ACTB	ENSPPYP00000018010	ENSPPYP00000019427	DBN1 isoform 4.	Actin, cytoplasmic 1, N-terminally processed; Actin is a highly conserved protein that polymerizes to produce filaments that form cross-linked networks in the cytoplasm of cells. Actin exists in both monomeric (G-actin) and polymeric (F-actin) forms, both forms playing key functions, such as cell motility and contraction. In addition to their role in the cytoplasmic cytoskeleton, G- and F-actin also localize in the nucleus, and regulate gene transcription and motility and repair of damaged DNA.	0.924
DBN1	CAPG	ENSPPYP00000018010	ENSPPYP00000013640	DBN1 isoform 4.	Capping actin protein, gelsolin like.	0.697
DBN1	CAPZB	ENSPPYP00000018010	ENSPPYP00000002072	DBN1 isoform 4.	F-actin-capping protein subunit beta; F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments. Plays a role in the regulation of cell morphology and cytoskeletal organization (By similarity).	0.742
DBN1	EPHA1	ENSPPYP00000018010	ENSPPYP00000020327	DBN1 isoform 4.	EPHA1 isoform 1.	0.723
DBN1	GSN	ENSPPYP00000018010	ENSPPYP00000021923	DBN1 isoform 4.	GSN isoform 1.	0.926
DBN1	HIP1R	ENSPPYP00000018010	ENSPPYP00000005782	DBN1 isoform 4.	HIP1R isoform 1.	0.728
DBN1	HOMER1	ENSPPYP00000018010	ENSPPYP00000017426	DBN1 isoform 4.	Homer scaffold protein 1.	0.776
DBN1	HOMER2	ENSPPYP00000018010	ENSPPYP00000007642	DBN1 isoform 4.	HOMER2 isoform 1.	0.809
DBN1	TMOD2	ENSPPYP00000018010	ENSPPYP00000007342	DBN1 isoform 4.	TMOD2 isoform 1.	0.772
DBN1	ZMYND8	ENSPPYP00000018010	ENSPPYP00000012404	DBN1 isoform 4.	ZMYND8 isoform 16.	0.766
EPHA1	DBN1	ENSPPYP00000020327	ENSPPYP00000018010	EPHA1 isoform 1.	DBN1 isoform 4.	0.723
EPHA1	HIP1R	ENSPPYP00000020327	ENSPPYP00000005782	EPHA1 isoform 1.	HIP1R isoform 1.	0.576