GRM6 protein (Pongo abelii) - STRING interaction network

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

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second shell of interactors

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proteins of unknown 3D structure

filled nodes:
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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

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Gene Fusion

Cooccurrence

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Experiments

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[Homology]

Score

GRM6

Glutamate metabotropic receptor 6. (877 aa)

Predicted Functional Partners:

AGT

0.924

GNA13

0.919

GNA12

0.919

F2

0.907

AVP

0.902

GNAS

0.901

LOC100437488

0.900

TRPM1

0.870

NYX

0.825

GRIK4

0.779

Your Current Organism:

Pongo abelii

NCBI taxonomy Id: 9601
Other names: Orang-utan, Orangutan, P. abelii, Pongo pygmaeus abeli, Pongo pygmaeus abelii, Sumatran orangutan, orang utan

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AGT	AVP	ENSPPYP00000000122	ENSPPYP00000012093	AGT isoform 1; Belongs to the serpin family.	AVP isoform 1; Belongs to the vasopressin/oxytocin family.	0.701
AGT	F2	ENSPPYP00000000122	ENSPPYP00000003807	AGT isoform 1; Belongs to the serpin family.	Activation peptide fragment 1; Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing (By similarity).	0.700
AGT	GNA12	ENSPPYP00000000122	ENSPPYP00000019410	AGT isoform 1; Belongs to the serpin family.	GNA12 isoform 1.	0.472
AGT	GRM6	ENSPPYP00000000122	ENSPPYP00000018032	AGT isoform 1; Belongs to the serpin family.	Glutamate metabotropic receptor 6.	0.924
AVP	AGT	ENSPPYP00000012093	ENSPPYP00000000122	AVP isoform 1; Belongs to the vasopressin/oxytocin family.	AGT isoform 1; Belongs to the serpin family.	0.701
AVP	F2	ENSPPYP00000012093	ENSPPYP00000003807	AVP isoform 1; Belongs to the vasopressin/oxytocin family.	Activation peptide fragment 1; Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing (By similarity).	0.405
AVP	GRM6	ENSPPYP00000012093	ENSPPYP00000018032	AVP isoform 1; Belongs to the vasopressin/oxytocin family.	Glutamate metabotropic receptor 6.	0.902
F2	AGT	ENSPPYP00000003807	ENSPPYP00000000122	Activation peptide fragment 1; Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing (By similarity).	AGT isoform 1; Belongs to the serpin family.	0.700
F2	AVP	ENSPPYP00000003807	ENSPPYP00000012093	Activation peptide fragment 1; Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing (By similarity).	AVP isoform 1; Belongs to the vasopressin/oxytocin family.	0.405
F2	GRM6	ENSPPYP00000003807	ENSPPYP00000018032	Activation peptide fragment 1; Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing (By similarity).	Glutamate metabotropic receptor 6.	0.907
GNA12	AGT	ENSPPYP00000019410	ENSPPYP00000000122	GNA12 isoform 1.	AGT isoform 1; Belongs to the serpin family.	0.472
GNA12	GNA13	ENSPPYP00000019410	ENSPPYP00000009607	GNA12 isoform 1.	G protein subunit alpha 13.	0.988
GNA12	GNAS	ENSPPYP00000019410	ENSPPYP00000012485	GNA12 isoform 1.	GNAS isoform 2.	0.695
GNA12	GRM6	ENSPPYP00000019410	ENSPPYP00000018032	GNA12 isoform 1.	Glutamate metabotropic receptor 6.	0.919
GNA13	GNA12	ENSPPYP00000009607	ENSPPYP00000019410	G protein subunit alpha 13.	GNA12 isoform 1.	0.988
GNA13	GNAS	ENSPPYP00000009607	ENSPPYP00000012485	G protein subunit alpha 13.	GNAS isoform 2.	0.463
GNA13	GRM6	ENSPPYP00000009607	ENSPPYP00000018032	G protein subunit alpha 13.	Glutamate metabotropic receptor 6.	0.919
GNAS	GNA12	ENSPPYP00000012485	ENSPPYP00000019410	GNAS isoform 2.	GNA12 isoform 1.	0.695
GNAS	GNA13	ENSPPYP00000012485	ENSPPYP00000009607	GNAS isoform 2.	G protein subunit alpha 13.	0.463
GNAS	GRM6	ENSPPYP00000012485	ENSPPYP00000018032	GNAS isoform 2.	Glutamate metabotropic receptor 6.	0.901