| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ARHGEF5 | CD8B | ENSPPYP00000020344 | ENSPPYP00000013609 | ARHGEF35 isoform 1. | CD8B isoform 1. | 0.671 |
| ARHGEF5 | DUSP22 | ENSPPYP00000020344 | ENSPPYP00000018076 | ARHGEF35 isoform 1. | Dual specificity phosphatase 22; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. | 0.778 |
| ARHGEF5 | NAIP | ENSPPYP00000020344 | ENSPPYP00000017359 | ARHGEF35 isoform 1. | NAIP isoform 3. | 0.616 |
| ARHGEF5 | PDZK1 | ENSPPYP00000020344 | ENSPPYP00000001092 | ARHGEF35 isoform 1. | Na(+)/H(+) exchange regulatory cofactor NHE-RF3; A scaffold protein that connects plasma membrane proteins and regulatory components, regulating their surface expression in epithelial cells apical domains. May be involved in the coordination of a diverse range of regulatory processes for ion transport and second messenger cascades. In complex with SLC9A3R1, may cluster proteins that are functionally dependent in a mutual fashion and modulate the trafficking and the activity of the associated membrane proteins. May play a role in the cellular mechanisms associated with multidrug resista [...] | 0.539 |
| ARHGEF5 | PTPN20 | ENSPPYP00000020344 | ENSPPYP00000002616 | ARHGEF35 isoform 1. | PTPN20 isoform 13. | 0.678 |
| ARHGEF5 | ROCK1 | ENSPPYP00000020344 | ENSPPYP00000010161 | ARHGEF35 isoform 1. | Rho-associated protein kinase; Protein kinase which is a key regulator of actin cytoskeleton and cell polarity. | 0.860 |
| ARHGEF5 | TCAF1 | ENSPPYP00000020344 | ENSPPYP00000020335 | ARHGEF35 isoform 1. | TRPM8 channel-associated factor 1; Positively regulates the plasma membrane cation channel TRPM8 activity. Involved in the recruitment of TRPM8 to the cell surface. Promotes prostate cancer cell migration inhibition in a TRPM8-dependent manner; Belongs to the TCAF family. | 0.734 |
| C19orf54 | DUSP22 | ENSPPYP00000011195 | ENSPPYP00000018076 | Chromosome 19 open reading frame 54. | Dual specificity phosphatase 22; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. | 0.659 |
| CD8B | ARHGEF5 | ENSPPYP00000013609 | ENSPPYP00000020344 | CD8B isoform 1. | ARHGEF35 isoform 1. | 0.671 |
| CD8B | DUSP22 | ENSPPYP00000013609 | ENSPPYP00000018076 | CD8B isoform 1. | Dual specificity phosphatase 22; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. | 0.721 |
| CD8B | NAIP | ENSPPYP00000013609 | ENSPPYP00000017359 | CD8B isoform 1. | NAIP isoform 3. | 0.679 |
| CD8B | PDZK1 | ENSPPYP00000013609 | ENSPPYP00000001092 | CD8B isoform 1. | Na(+)/H(+) exchange regulatory cofactor NHE-RF3; A scaffold protein that connects plasma membrane proteins and regulatory components, regulating their surface expression in epithelial cells apical domains. May be involved in the coordination of a diverse range of regulatory processes for ion transport and second messenger cascades. In complex with SLC9A3R1, may cluster proteins that are functionally dependent in a mutual fashion and modulate the trafficking and the activity of the associated membrane proteins. May play a role in the cellular mechanisms associated with multidrug resista [...] | 0.672 |
| CD8B | PTPN20 | ENSPPYP00000013609 | ENSPPYP00000002616 | CD8B isoform 1. | PTPN20 isoform 13. | 0.655 |
| CD8B | ROCK1 | ENSPPYP00000013609 | ENSPPYP00000010161 | CD8B isoform 1. | Rho-associated protein kinase; Protein kinase which is a key regulator of actin cytoskeleton and cell polarity. | 0.551 |
| CD8B | TCAF1 | ENSPPYP00000013609 | ENSPPYP00000020335 | CD8B isoform 1. | TRPM8 channel-associated factor 1; Positively regulates the plasma membrane cation channel TRPM8 activity. Involved in the recruitment of TRPM8 to the cell surface. Promotes prostate cancer cell migration inhibition in a TRPM8-dependent manner; Belongs to the TCAF family. | 0.743 |
| DUSP22 | ARHGEF5 | ENSPPYP00000018076 | ENSPPYP00000020344 | Dual specificity phosphatase 22; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. | ARHGEF35 isoform 1. | 0.778 |
| DUSP22 | C19orf54 | ENSPPYP00000018076 | ENSPPYP00000011195 | Dual specificity phosphatase 22; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. | Chromosome 19 open reading frame 54. | 0.659 |
| DUSP22 | CD8B | ENSPPYP00000018076 | ENSPPYP00000013609 | Dual specificity phosphatase 22; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. | CD8B isoform 1. | 0.721 |
| DUSP22 | FUNDC2 | ENSPPYP00000018076 | ENSPPYP00000023394 | Dual specificity phosphatase 22; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. | FUN14 domain containing 2. | 0.636 |
| DUSP22 | NAIP | ENSPPYP00000018076 | ENSPPYP00000017359 | Dual specificity phosphatase 22; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. | NAIP isoform 3. | 0.722 |
