| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| BIRC2 | CASP8 | ENSPPYP00000004356 | ENSPPYP00000014605 | Baculoviral IAP repeat containing 2. | CASP8 isoform 1; Belongs to the peptidase C14A family. | 0.908 |
| BIRC2 | CHUK | ENSPPYP00000004356 | ENSPPYP00000002975 | Baculoviral IAP repeat containing 2. | CHUK isoform 1. | 0.816 |
| BIRC2 | CR201_G0015089 | ENSPPYP00000004356 | ENSPPYP00000008406 | Baculoviral IAP repeat containing 2. | TRADD isoform 2. | 0.978 |
| BIRC2 | FADD | ENSPPYP00000004356 | ENSPPYP00000003427 | Baculoviral IAP repeat containing 2. | FAS-associated death domain protein; Apoptotic adaptor molecule that recruits caspase-8 or caspase-10 to the activated Fas (CD95) or TNFR-1 receptors. The resulting aggregate called the death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation. Active caspase-8 initiates the subsequent cascade of caspases mediating apoptosis. Involved in interferon-mediated antiviral immune response, playing a role in the positive regulation of interferon signaling. | 0.955 |
| BIRC2 | IKBKG | ENSPPYP00000004356 | ENSPPYP00000023381 | Baculoviral IAP repeat containing 2. | Inhibitor of nuclear factor kappa B kinase regulatory subunit gamma. | 0.978 |
| BIRC2 | RIPK1 | ENSPPYP00000004356 | ENSPPYP00000018096 | Baculoviral IAP repeat containing 2. | Receptor interacting serine/threonine kinase 1. | 0.997 |
| BIRC2 | RIPK3 | ENSPPYP00000004356 | ENSPPYP00000006485 | Baculoviral IAP repeat containing 2. | Receptor interacting serine/threonine kinase 3. | 0.965 |
| BIRC2 | TNFRSF1A | ENSPPYP00000004356 | ENSPPYP00000004766 | Baculoviral IAP repeat containing 2. | TNFRSF1A isoform 2. | 0.997 |
| BIRC2 | TRAF2 | ENSPPYP00000004356 | ENSPPYP00000022191 | Baculoviral IAP repeat containing 2. | TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. | 0.997 |
| BIRC2 | USP21 | ENSPPYP00000004356 | ENSPPYP00000000711 | Baculoviral IAP repeat containing 2. | Ubiquitin carboxyl-terminal hydrolase; Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes. Belongs to the peptidase C19 family. | 0.404 |
| CASP8 | BIRC2 | ENSPPYP00000014605 | ENSPPYP00000004356 | CASP8 isoform 1; Belongs to the peptidase C14A family. | Baculoviral IAP repeat containing 2. | 0.908 |
| CASP8 | CHUK | ENSPPYP00000014605 | ENSPPYP00000002975 | CASP8 isoform 1; Belongs to the peptidase C14A family. | CHUK isoform 1. | 0.720 |
| CASP8 | CR201_G0015089 | ENSPPYP00000014605 | ENSPPYP00000008406 | CASP8 isoform 1; Belongs to the peptidase C14A family. | TRADD isoform 2. | 0.979 |
| CASP8 | FADD | ENSPPYP00000014605 | ENSPPYP00000003427 | CASP8 isoform 1; Belongs to the peptidase C14A family. | FAS-associated death domain protein; Apoptotic adaptor molecule that recruits caspase-8 or caspase-10 to the activated Fas (CD95) or TNFR-1 receptors. The resulting aggregate called the death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation. Active caspase-8 initiates the subsequent cascade of caspases mediating apoptosis. Involved in interferon-mediated antiviral immune response, playing a role in the positive regulation of interferon signaling. | 0.999 |
| CASP8 | IKBKG | ENSPPYP00000014605 | ENSPPYP00000023381 | CASP8 isoform 1; Belongs to the peptidase C14A family. | Inhibitor of nuclear factor kappa B kinase regulatory subunit gamma. | 0.751 |
| CASP8 | RIPK1 | ENSPPYP00000014605 | ENSPPYP00000018096 | CASP8 isoform 1; Belongs to the peptidase C14A family. | Receptor interacting serine/threonine kinase 1. | 0.999 |
| CASP8 | RIPK3 | ENSPPYP00000014605 | ENSPPYP00000006485 | CASP8 isoform 1; Belongs to the peptidase C14A family. | Receptor interacting serine/threonine kinase 3. | 0.998 |
| CASP8 | TNFRSF1A | ENSPPYP00000014605 | ENSPPYP00000004766 | CASP8 isoform 1; Belongs to the peptidase C14A family. | TNFRSF1A isoform 2. | 0.869 |
| CASP8 | TRAF2 | ENSPPYP00000014605 | ENSPPYP00000022191 | CASP8 isoform 1; Belongs to the peptidase C14A family. | TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. | 0.969 |
| CHUK | BIRC2 | ENSPPYP00000002975 | ENSPPYP00000004356 | CHUK isoform 1. | Baculoviral IAP repeat containing 2. | 0.816 |
