ECI2 protein (Pongo abelii) - STRING interaction network

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second shell of interactors

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Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

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textmining

co-expression

protein homology

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[Homology]

Score

ECI2

ECI2 isoform 1. (392 aa)

Predicted Functional Partners:

HADHB

0.984

ACAA1

0.984

ACAA2

0.983

ACAT1

0.980

CARTPT

0.980

ACAT2

0.980

SCP2

0.979

EHHADH

0.960

HSDL2

0.950

PEX5

0.936

Your Current Organism:

Pongo abelii

NCBI taxonomy Id: 9601
Other names: Orang-utan, Orangutan, P. abelii, Pongo pygmaeus abeli, Pongo pygmaeus abelii, Sumatran orangutan, orang utan

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ACAA1	ACAT1	ENSPPYP00000015674	ENSPPYP00000004400	Acetyl-CoA acyltransferase 1; Belongs to the thiolase-like superfamily. Thiolase family.	Acetyl-CoA acetyltransferase 1; Belongs to the thiolase-like superfamily. Thiolase family.	0.925
ACAA1	ACAT2	ENSPPYP00000015674	ENSPPYP00000019199	Acetyl-CoA acyltransferase 1; Belongs to the thiolase-like superfamily. Thiolase family.	Acetyl-CoA acetyltransferase 2; Belongs to the thiolase-like superfamily. Thiolase family.	0.919
ACAA1	ECI2	ENSPPYP00000015674	ENSPPYP00000018110	Acetyl-CoA acyltransferase 1; Belongs to the thiolase-like superfamily. Thiolase family.	ECI2 isoform 1.	0.984
ACAA1	EHHADH	ENSPPYP00000015674	ENSPPYP00000016064	Acetyl-CoA acyltransferase 1; Belongs to the thiolase-like superfamily. Thiolase family.	Enoyl-CoA hydratase/3,2-trans-enoyl-CoA isomerase; In the N-terminal section; belongs to the enoyl-CoA hydratase/isomerase family.	0.993
ACAA1	HADHB	ENSPPYP00000015674	ENSPPYP00000014050	Acetyl-CoA acyltransferase 1; Belongs to the thiolase-like superfamily. Thiolase family.	HADHB isoform 3; Belongs to the thiolase-like superfamily. Thiolase family.	0.934
ACAA1	HSDL2	ENSPPYP00000015674	ENSPPYP00000021856	Acetyl-CoA acyltransferase 1; Belongs to the thiolase-like superfamily. Thiolase family.	Hydroxysteroid dehydrogenase-like protein 2; Has apparently no steroid dehydrogenase activity. Belongs to the short-chain dehydrogenases/reductases (SDR) family.	0.941
ACAA1	PEX5	ENSPPYP00000015674	ENSPPYP00000004816	Acetyl-CoA acyltransferase 1; Belongs to the thiolase-like superfamily. Thiolase family.	Peroxisomal biogenesis factor 5.	0.821
ACAA1	SCP2	ENSPPYP00000015674	ENSPPYP00000001558	Acetyl-CoA acyltransferase 1; Belongs to the thiolase-like superfamily. Thiolase family.	SCP2 isoform 1; Belongs to the thiolase-like superfamily. Thiolase family.	0.969
ACAA2	ECI2	ENSPPYP00000010284	ENSPPYP00000018110	3-ketoacyl-CoA thiolase, mitochondrial; In the production of energy from fats, this is one of the enzymes that catalyzes the last step of the mitochondrial beta- oxidation pathway, an aerobic process breaking down fatty acids into acetyl-CoA. Using free coenzyme A/CoA, catalyzes the thiolytic cleavage of medium- to long-chain unbranched 3-oxoacyl-CoAs into acetyl-CoA and a fatty acyl-CoA shortened by two carbon atoms. Also catalyzes the condensation of two acetyl-CoA molecules into acetoacetyl-CoA and could be involved in the production of ketone bodies. Also displays hydrolase activit [...]	ECI2 isoform 1.	0.983
ACAA2	EHHADH	ENSPPYP00000010284	ENSPPYP00000016064	3-ketoacyl-CoA thiolase, mitochondrial; In the production of energy from fats, this is one of the enzymes that catalyzes the last step of the mitochondrial beta- oxidation pathway, an aerobic process breaking down fatty acids into acetyl-CoA. Using free coenzyme A/CoA, catalyzes the thiolytic cleavage of medium- to long-chain unbranched 3-oxoacyl-CoAs into acetyl-CoA and a fatty acyl-CoA shortened by two carbon atoms. Also catalyzes the condensation of two acetyl-CoA molecules into acetoacetyl-CoA and could be involved in the production of ketone bodies. Also displays hydrolase activit [...]	Enoyl-CoA hydratase/3,2-trans-enoyl-CoA isomerase; In the N-terminal section; belongs to the enoyl-CoA hydratase/isomerase family.	0.907
ACAA2	HADHB	ENSPPYP00000010284	ENSPPYP00000014050	3-ketoacyl-CoA thiolase, mitochondrial; In the production of energy from fats, this is one of the enzymes that catalyzes the last step of the mitochondrial beta- oxidation pathway, an aerobic process breaking down fatty acids into acetyl-CoA. Using free coenzyme A/CoA, catalyzes the thiolytic cleavage of medium- to long-chain unbranched 3-oxoacyl-CoAs into acetyl-CoA and a fatty acyl-CoA shortened by two carbon atoms. Also catalyzes the condensation of two acetyl-CoA molecules into acetoacetyl-CoA and could be involved in the production of ketone bodies. Also displays hydrolase activit [...]	HADHB isoform 3; Belongs to the thiolase-like superfamily. Thiolase family.	0.630
ACAA2	HSDL2	ENSPPYP00000010284	ENSPPYP00000021856	3-ketoacyl-CoA thiolase, mitochondrial; In the production of energy from fats, this is one of the enzymes that catalyzes the last step of the mitochondrial beta- oxidation pathway, an aerobic process breaking down fatty acids into acetyl-CoA. Using free coenzyme A/CoA, catalyzes the thiolytic cleavage of medium- to long-chain unbranched 3-oxoacyl-CoAs into acetyl-CoA and a fatty acyl-CoA shortened by two carbon atoms. Also catalyzes the condensation of two acetyl-CoA molecules into acetoacetyl-CoA and could be involved in the production of ketone bodies. Also displays hydrolase activit [...]	Hydroxysteroid dehydrogenase-like protein 2; Has apparently no steroid dehydrogenase activity. Belongs to the short-chain dehydrogenases/reductases (SDR) family.	0.936
ACAA2	PEX5	ENSPPYP00000010284	ENSPPYP00000004816	3-ketoacyl-CoA thiolase, mitochondrial; In the production of energy from fats, this is one of the enzymes that catalyzes the last step of the mitochondrial beta- oxidation pathway, an aerobic process breaking down fatty acids into acetyl-CoA. Using free coenzyme A/CoA, catalyzes the thiolytic cleavage of medium- to long-chain unbranched 3-oxoacyl-CoAs into acetyl-CoA and a fatty acyl-CoA shortened by two carbon atoms. Also catalyzes the condensation of two acetyl-CoA molecules into acetoacetyl-CoA and could be involved in the production of ketone bodies. Also displays hydrolase activit [...]	Peroxisomal biogenesis factor 5.	0.638
ACAA2	SCP2	ENSPPYP00000010284	ENSPPYP00000001558	3-ketoacyl-CoA thiolase, mitochondrial; In the production of energy from fats, this is one of the enzymes that catalyzes the last step of the mitochondrial beta- oxidation pathway, an aerobic process breaking down fatty acids into acetyl-CoA. Using free coenzyme A/CoA, catalyzes the thiolytic cleavage of medium- to long-chain unbranched 3-oxoacyl-CoAs into acetyl-CoA and a fatty acyl-CoA shortened by two carbon atoms. Also catalyzes the condensation of two acetyl-CoA molecules into acetoacetyl-CoA and could be involved in the production of ketone bodies. Also displays hydrolase activit [...]	SCP2 isoform 1; Belongs to the thiolase-like superfamily. Thiolase family.	0.717
ACAT1	ACAA1	ENSPPYP00000004400	ENSPPYP00000015674	Acetyl-CoA acetyltransferase 1; Belongs to the thiolase-like superfamily. Thiolase family.	Acetyl-CoA acyltransferase 1; Belongs to the thiolase-like superfamily. Thiolase family.	0.925
ACAT1	ACAT2	ENSPPYP00000004400	ENSPPYP00000019199	Acetyl-CoA acetyltransferase 1; Belongs to the thiolase-like superfamily. Thiolase family.	Acetyl-CoA acetyltransferase 2; Belongs to the thiolase-like superfamily. Thiolase family.	0.917
ACAT1	ECI2	ENSPPYP00000004400	ENSPPYP00000018110	Acetyl-CoA acetyltransferase 1; Belongs to the thiolase-like superfamily. Thiolase family.	ECI2 isoform 1.	0.980
ACAT1	EHHADH	ENSPPYP00000004400	ENSPPYP00000016064	Acetyl-CoA acetyltransferase 1; Belongs to the thiolase-like superfamily. Thiolase family.	Enoyl-CoA hydratase/3,2-trans-enoyl-CoA isomerase; In the N-terminal section; belongs to the enoyl-CoA hydratase/isomerase family.	0.972
ACAT1	HADHB	ENSPPYP00000004400	ENSPPYP00000014050	Acetyl-CoA acetyltransferase 1; Belongs to the thiolase-like superfamily. Thiolase family.	HADHB isoform 3; Belongs to the thiolase-like superfamily. Thiolase family.	0.928
ACAT1	HSDL2	ENSPPYP00000004400	ENSPPYP00000021856	Acetyl-CoA acetyltransferase 1; Belongs to the thiolase-like superfamily. Thiolase family.	Hydroxysteroid dehydrogenase-like protein 2; Has apparently no steroid dehydrogenase activity. Belongs to the short-chain dehydrogenases/reductases (SDR) family.	0.930