Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
TFAP2ATranscription factor AP-2 alpha. (439 aa)    
Predicted Functional Partners:
TFAP2B
TFAP2B isoform 1.
   
 0.995
TFAP2E
TFAP2E isoform 1.
   
 0.990
TFAP2C
TFAP2C isoform 1.
   
 0.965
GSTO2
Glutathione S-transferase omega 2; Belongs to the GST superfamily.
    
 
 0.918
TFAP2D
Transcription factor AP-2 delta.
   
 0.912
CITED2
Cbp/p300 interacting transactivator with Glu/Asp rich carboxy-terminal domain 2.
    
 0.842
DEK
DEK isoform 1.
    
 0.818
CBFA2T2
CBFA2T2 isoform 3.
     
 0.804
SP1
Sp1 transcription factor.
    
 0.793
MSX1
MSX1 isoform 1.
   
 0.737
Your Current Organism:
Pongo abelii
NCBI taxonomy Id: 9601
Other names: Orang-utan, Orangutan, P. abelii, Pongo pygmaeus abeli, Pongo pygmaeus abelii, Sumatran orangutan, orang utan
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