Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
MHC-Poab-CMHC class I antigen; Belongs to the MHC class I family. (364 aa)    
Predicted Functional Partners:
B2M
Beta-2-microglobulin; Component of the class I major histocompatibility complex (MHC). Involved in the presentation of peptide antigens to the immune system.
   
  0.959
CR201_G0049459
CD8A isoform 1.
   
 0.956
TAPBP
TAPBP isoform 1.
   
 0.949
PDIA3
Protein disulfide-isomerase A3.
    
 0.946
CALR
Calreticulin.
    
  0.943
CD8B
CD8B isoform 1.
     
  0.928
CR201_G0055131
IGHV3-21 isoform 1.
    
  0.905
TAPBPL
Tapasin-related protein; Component of the antigen processing and presentation pathway, which binds to MHC class I coupled with beta2-microglobulin/B2M. Association between TAPBPR and MHC class I occurs in the absence of a functional peptide-loading complex (PLC). Expression seems to slow down and down-regulate MHC class I surface expression.
   
 
  0.901
KLRD1
KLRD1 isoform 1.
    
 0.820
CR201_G0051047
T0180641 isoform 1.
    
 0.729
Your Current Organism:
Pongo abelii
NCBI taxonomy Id: 9601
Other names: Orang-utan, Orangutan, P. abelii, Pongo pygmaeus abeli, Pongo pygmaeus abelii, Sumatran orangutan, orang utan
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