Export your current network:
... as a vector graphic:
SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc
... as short tabular text output:
TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)
... as tabular text output:
TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)
... as an XML summary:
structured XML interaction data, according to the 'PSI-MI' data standard
... protein node degrees:
node degree of proteins in your network (given the current score cut-off)
... network coordinates:
a flat-file format describing the coordinates and colors of nodes in the network
... protein sequences:
MFA: multi-fasta format - containing the aminoacid sequences in the network
... protein annotations:
a tab-delimited file describing the names, domains and descriptions of proteins in your network
... functional annotations:
a tab-delimited file containing all known functional terms of proteins in your network
Browse interactions in tabular form:
| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| DNAJB1 | DNAJB4 | ENSPPYP00000010811 | ENSPPYP00000001411 | DnaJ heat shock protein family (Hsp40) member B1. | DnaJ homolog subfamily B member 4; Probable chaperone. Stimulates ATP hydrolysis and the folding of unfolded proteins mediated by HSPA1A/B (in vitro). | 0.863 |
| DNAJB1 | HSP90AB1 | ENSPPYP00000010811 | ENSPPYP00000018631 | DnaJ heat shock protein family (Hsp40) member B1. | Heat shock protein HSP 90-beta; Molecular chaperone that promotes the maturation, structural maintenance and proper regulation of specific target proteins involved for instance in cell cycle control and signal transduction. Undergoes a functional cycle that is linked to its ATPase activity. This cycle probably induces conformational changes in the client proteins, thereby causing their activation. Interacts dynamically with various co- chaperones that modulate its substrate recognition, ATPase cycle and chaperone function. Engages with a range of client protein classes via its interact [...] | 0.981 |
| DNAJB1 | HSPA1L | ENSPPYP00000010811 | ENSPPYP00000018406 | DnaJ heat shock protein family (Hsp40) member B1. | Heat shock protein family A (Hsp70) member 1 like; Belongs to the heat shock protein 70 family. | 0.875 |
| DNAJB1 | NR3C1 | ENSPPYP00000010811 | ENSPPYP00000017784 | DnaJ heat shock protein family (Hsp40) member B1. | Glucocorticoid receptor; Receptor for glucocorticoids (GC). Has a dual mode of action: as a transcription factor that binds to glucocorticoid response elements (GRE), both for nuclear and mitochondrial DNA, and as a modulator of other transcription factors. Affects inflammatory responses, cellular proliferation and differentiation in target tissues. Involved in chromatin remodeling. Plays a role in rapid mRNA degradation by binding to the 5' UTR of target mRNAs and interacting with PNRC2 in a ligand-dependent manner which recruits the RNA helicase UPF1 and the mRNA-decapping enzyme DCP [...] | 0.458 |
| DNAJB1 | STIP1 | ENSPPYP00000010811 | ENSPPYP00000003602 | DnaJ heat shock protein family (Hsp40) member B1. | STIP1 isoform 2. | 0.940 |
| DNAJB4 | DNAJB1 | ENSPPYP00000001411 | ENSPPYP00000010811 | DnaJ homolog subfamily B member 4; Probable chaperone. Stimulates ATP hydrolysis and the folding of unfolded proteins mediated by HSPA1A/B (in vitro). | DnaJ heat shock protein family (Hsp40) member B1. | 0.863 |
| DNAJB4 | HSP90AB1 | ENSPPYP00000001411 | ENSPPYP00000018631 | DnaJ homolog subfamily B member 4; Probable chaperone. Stimulates ATP hydrolysis and the folding of unfolded proteins mediated by HSPA1A/B (in vitro). | Heat shock protein HSP 90-beta; Molecular chaperone that promotes the maturation, structural maintenance and proper regulation of specific target proteins involved for instance in cell cycle control and signal transduction. Undergoes a functional cycle that is linked to its ATPase activity. This cycle probably induces conformational changes in the client proteins, thereby causing their activation. Interacts dynamically with various co- chaperones that modulate its substrate recognition, ATPase cycle and chaperone function. Engages with a range of client protein classes via its interact [...] | 0.672 |
| DNAJB4 | HSPA1L | ENSPPYP00000001411 | ENSPPYP00000018406 | DnaJ homolog subfamily B member 4; Probable chaperone. Stimulates ATP hydrolysis and the folding of unfolded proteins mediated by HSPA1A/B (in vitro). | Heat shock protein family A (Hsp70) member 1 like; Belongs to the heat shock protein 70 family. | 0.875 |
| DNAJB4 | STIP1 | ENSPPYP00000001411 | ENSPPYP00000003602 | DnaJ homolog subfamily B member 4; Probable chaperone. Stimulates ATP hydrolysis and the folding of unfolded proteins mediated by HSPA1A/B (in vitro). | STIP1 isoform 2. | 0.751 |
| GAK | HSPA1L | ENSPPYP00000016219 | ENSPPYP00000018406 | GAK isoform 7. | Heat shock protein family A (Hsp70) member 1 like; Belongs to the heat shock protein 70 family. | 0.930 |
| HSP90AB1 | DNAJB1 | ENSPPYP00000018631 | ENSPPYP00000010811 | Heat shock protein HSP 90-beta; Molecular chaperone that promotes the maturation, structural maintenance and proper regulation of specific target proteins involved for instance in cell cycle control and signal transduction. Undergoes a functional cycle that is linked to its ATPase activity. This cycle probably induces conformational changes in the client proteins, thereby causing their activation. Interacts dynamically with various co- chaperones that modulate its substrate recognition, ATPase cycle and chaperone function. Engages with a range of client protein classes via its interact [...] | DnaJ heat shock protein family (Hsp40) member B1. | 0.981 |
| HSP90AB1 | DNAJB4 | ENSPPYP00000018631 | ENSPPYP00000001411 | Heat shock protein HSP 90-beta; Molecular chaperone that promotes the maturation, structural maintenance and proper regulation of specific target proteins involved for instance in cell cycle control and signal transduction. Undergoes a functional cycle that is linked to its ATPase activity. This cycle probably induces conformational changes in the client proteins, thereby causing their activation. Interacts dynamically with various co- chaperones that modulate its substrate recognition, ATPase cycle and chaperone function. Engages with a range of client protein classes via its interact [...] | DnaJ homolog subfamily B member 4; Probable chaperone. Stimulates ATP hydrolysis and the folding of unfolded proteins mediated by HSPA1A/B (in vitro). | 0.672 |
| HSP90AB1 | HSPA1L | ENSPPYP00000018631 | ENSPPYP00000018406 | Heat shock protein HSP 90-beta; Molecular chaperone that promotes the maturation, structural maintenance and proper regulation of specific target proteins involved for instance in cell cycle control and signal transduction. Undergoes a functional cycle that is linked to its ATPase activity. This cycle probably induces conformational changes in the client proteins, thereby causing their activation. Interacts dynamically with various co- chaperones that modulate its substrate recognition, ATPase cycle and chaperone function. Engages with a range of client protein classes via its interact [...] | Heat shock protein family A (Hsp70) member 1 like; Belongs to the heat shock protein 70 family. | 0.862 |
| HSP90AB1 | NR3C1 | ENSPPYP00000018631 | ENSPPYP00000017784 | Heat shock protein HSP 90-beta; Molecular chaperone that promotes the maturation, structural maintenance and proper regulation of specific target proteins involved for instance in cell cycle control and signal transduction. Undergoes a functional cycle that is linked to its ATPase activity. This cycle probably induces conformational changes in the client proteins, thereby causing their activation. Interacts dynamically with various co- chaperones that modulate its substrate recognition, ATPase cycle and chaperone function. Engages with a range of client protein classes via its interact [...] | Glucocorticoid receptor; Receptor for glucocorticoids (GC). Has a dual mode of action: as a transcription factor that binds to glucocorticoid response elements (GRE), both for nuclear and mitochondrial DNA, and as a modulator of other transcription factors. Affects inflammatory responses, cellular proliferation and differentiation in target tissues. Involved in chromatin remodeling. Plays a role in rapid mRNA degradation by binding to the 5' UTR of target mRNAs and interacting with PNRC2 in a ligand-dependent manner which recruits the RNA helicase UPF1 and the mRNA-decapping enzyme DCP [...] | 0.922 |
| HSP90AB1 | STIP1 | ENSPPYP00000018631 | ENSPPYP00000003602 | Heat shock protein HSP 90-beta; Molecular chaperone that promotes the maturation, structural maintenance and proper regulation of specific target proteins involved for instance in cell cycle control and signal transduction. Undergoes a functional cycle that is linked to its ATPase activity. This cycle probably induces conformational changes in the client proteins, thereby causing their activation. Interacts dynamically with various co- chaperones that modulate its substrate recognition, ATPase cycle and chaperone function. Engages with a range of client protein classes via its interact [...] | STIP1 isoform 2. | 0.993 |
| HSP90AB1 | TLR2 | ENSPPYP00000018631 | ENSPPYP00000016910 | Heat shock protein HSP 90-beta; Molecular chaperone that promotes the maturation, structural maintenance and proper regulation of specific target proteins involved for instance in cell cycle control and signal transduction. Undergoes a functional cycle that is linked to its ATPase activity. This cycle probably induces conformational changes in the client proteins, thereby causing their activation. Interacts dynamically with various co- chaperones that modulate its substrate recognition, ATPase cycle and chaperone function. Engages with a range of client protein classes via its interact [...] | Toll-like receptor. | 0.827 |
| HSPA1L | DNAJB1 | ENSPPYP00000018406 | ENSPPYP00000010811 | Heat shock protein family A (Hsp70) member 1 like; Belongs to the heat shock protein 70 family. | DnaJ heat shock protein family (Hsp40) member B1. | 0.875 |
| HSPA1L | DNAJB4 | ENSPPYP00000018406 | ENSPPYP00000001411 | Heat shock protein family A (Hsp70) member 1 like; Belongs to the heat shock protein 70 family. | DnaJ homolog subfamily B member 4; Probable chaperone. Stimulates ATP hydrolysis and the folding of unfolded proteins mediated by HSPA1A/B (in vitro). | 0.875 |
| HSPA1L | GAK | ENSPPYP00000018406 | ENSPPYP00000016219 | Heat shock protein family A (Hsp70) member 1 like; Belongs to the heat shock protein 70 family. | GAK isoform 7. | 0.930 |
| HSPA1L | HSP90AB1 | ENSPPYP00000018406 | ENSPPYP00000018631 | Heat shock protein family A (Hsp70) member 1 like; Belongs to the heat shock protein 70 family. | Heat shock protein HSP 90-beta; Molecular chaperone that promotes the maturation, structural maintenance and proper regulation of specific target proteins involved for instance in cell cycle control and signal transduction. Undergoes a functional cycle that is linked to its ATPase activity. This cycle probably induces conformational changes in the client proteins, thereby causing their activation. Interacts dynamically with various co- chaperones that modulate its substrate recognition, ATPase cycle and chaperone function. Engages with a range of client protein classes via its interact [...] | 0.862 |
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