STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SLC44A4SLC44A4 isoform 2; Belongs to the CTL (choline transporter-like) family. (712 aa)    
Predicted Functional Partners:
SLC22A1
Solute carrier family 22 member 1.
   
 
 0.927
SLC22A2
Solute carrier family 22 member 2; Mediates tubular uptake of organic compounds from circulation. Mediates the influx of agmatine, dopamine, noradrenaline (norepinephrine), serotonin, choline, famotidine, ranitidine, histamine, creatinine, amantadine, memantine, acriflavine, 4-[4- (dimethylamino)-styryl]-N-methylpyridinium ASP, amiloride, metformin, N-1-methylnicotinamide (NMN), tetraethylammonium (TEA), 1-methyl-4- phenylpyridinium (MPP), cimetidine, cisplatin and oxaliplatin. Cisplatin may develop a nephrotoxic action. Transport of creatinine is inhibited by fluoroquinolones such as [...]
   
 
 0.927
SLC22A3
Solute carrier family 22 member 3.
   
 
 0.925
SLC44A3
SLC44A3 isoform 1; Belongs to the CTL (choline transporter-like) family.
  
 
0.918
SLC22A5
SLC22A5 isoform 1.
   
 
 0.913
SLC44A5
SLC44A5 isoform 1; Belongs to the CTL (choline transporter-like) family.
  
  
 
0.903
CD80
CD80 isoform 4.
      
 0.687
CD86
CD86 isoform 2.
      
 0.645
CLMP
CLMP isoform 1.
      
 0.560
TTC6
TTC6 isoform 3.
   
    0.548
Your Current Organism:
Pongo abelii
NCBI taxonomy Id: 9601
Other names: Orang-utan, Orangutan, P. abelii, Pongo pygmaeus abeli, Pongo pygmaeus abelii, Sumatran orangutan, orang utan
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.