Export your current network:
... as a bitmap image:
file format is 'PNG': portable network graphic
... as a high-resolution bitmap:
same PNG format, but at higher resolution
... as a vector graphic:
SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc
... as short tabular text output:
TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)
... as tabular text output:
TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)
... as an XML summary:
structured XML interaction data, according to the 'PSI-MI' data standard
... protein node degrees:
node degree of proteins in your network (given the current score cut-off)
... network coordinates:
a flat-file format describing the coordinates and colors of nodes in the network
... protein sequences:
MFA: multi-fasta format - containing the aminoacid sequences in the network
... protein annotations:
a tab-delimited file describing the names, domains and descriptions of proteins in your network
... functional annotations:
a tab-delimited file containing all known functional terms of protiens in your network
Browse interactions in tabular form:
node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
DKFZp468G2216 | ENSPPYP00000017062 | ENSPPYP00000022865 | ENSPPYP00000017062 | AR isoform 8. | annotation not available | 0.750 |
DKFZp468G2216 | FKBP4 | ENSPPYP00000022865 | ENSPPYP00000004732 | AR isoform 8. | Peptidylprolyl isomerase. | 0.939 |
DKFZp468G2216 | FKBP5 | ENSPPYP00000022865 | ENSPPYP00000018489 | AR isoform 8. | Peptidyl-prolyl cis-trans isomerase FKBP5; Immunophilin protein with PPIase and co-chaperone activities. Component of unligated steroid receptors heterocomplexes through interaction with heat-shock protein 90 (HSP90). Plays a role in the intracellular trafficking of heterooligomeric forms of steroid hormone receptors maintaining the complex into the cytoplasm when unliganded (By similarity). | 0.885 |
DKFZp468G2216 | HSP90AA1 | ENSPPYP00000022865 | ENSPPYP00000006994 | AR isoform 8. | HSP90AA1 isoform 6. | 0.973 |
DKFZp468G2216 | HSP90AB1 | ENSPPYP00000022865 | ENSPPYP00000018631 | AR isoform 8. | Heat shock protein HSP 90-beta; Molecular chaperone that promotes the maturation, structural maintenance and proper regulation of specific target proteins involved for instance in cell cycle control and signal transduction. Undergoes a functional cycle that is linked to its ATPase activity. This cycle probably induces conformational changes in the client proteins, thereby causing their activation. Interacts dynamically with various co- chaperones that modulate its substrate recognition, ATPase cycle and chaperone function. Engages with a range of client protein classes via its interact [...] | 0.989 |
DKFZp468G2216 | HSPA4 | ENSPPYP00000022865 | ENSPPYP00000017643 | AR isoform 8. | Heat shock 70 kDa protein 4; Belongs to the heat shock protein 70 family. | 0.728 |
DKFZp468G2216 | NR3C1 | ENSPPYP00000022865 | ENSPPYP00000017784 | AR isoform 8. | Glucocorticoid receptor; Receptor for glucocorticoids (GC). Has a dual mode of action: as a transcription factor that binds to glucocorticoid response elements (GRE), both for nuclear and mitochondrial DNA, and as a modulator of other transcription factors. Affects inflammatory responses, cellular proliferation and differentiation in target tissues. Involved in chromatin remodeling. Plays a role in rapid mRNA degradation by binding to the 5' UTR of target mRNAs and interacting with PNRC2 in a ligand-dependent manner which recruits the RNA helicase UPF1 and the mRNA-decapping enzyme DCP [...] | 0.704 |
DKFZp468G2216 | PGR | ENSPPYP00000022865 | ENSPPYP00000004346 | AR isoform 8. | PGR isoform 1. | 0.676 |
DKFZp468G2216 | PTGES3 | ENSPPYP00000022865 | ENSPPYP00000005319 | AR isoform 8. | Prostaglandin E synthase 3; Cytosolic prostaglandin synthase that catalyzes the oxidoreduction of prostaglandin endoperoxide H2 (PGH2) to prostaglandin E2 (PGE2). Molecular chaperone that localizes to genomic response elements in a hormone-dependent manner and disrupts receptor-mediated transcriptional activation, by promoting disassembly of transcriptional regulatory complexes. Facilitates HIF alpha proteins hydroxylation via interaction with EGLN1/PHD2, leading to recruit EGLN1/PHD2 to the HSP90 pathway. | 0.730 |
ENSPPYP00000017062 | DKFZp468G2216 | ENSPPYP00000017062 | ENSPPYP00000022865 | annotation not available | AR isoform 8. | 0.750 |
ENSPPYP00000017062 | FKBP4 | ENSPPYP00000017062 | ENSPPYP00000004732 | annotation not available | Peptidylprolyl isomerase. | 0.763 |
ENSPPYP00000017062 | FKBP5 | ENSPPYP00000017062 | ENSPPYP00000018489 | annotation not available | Peptidyl-prolyl cis-trans isomerase FKBP5; Immunophilin protein with PPIase and co-chaperone activities. Component of unligated steroid receptors heterocomplexes through interaction with heat-shock protein 90 (HSP90). Plays a role in the intracellular trafficking of heterooligomeric forms of steroid hormone receptors maintaining the complex into the cytoplasm when unliganded (By similarity). | 0.885 |
ENSPPYP00000017062 | HSP90AB1 | ENSPPYP00000017062 | ENSPPYP00000018631 | annotation not available | Heat shock protein HSP 90-beta; Molecular chaperone that promotes the maturation, structural maintenance and proper regulation of specific target proteins involved for instance in cell cycle control and signal transduction. Undergoes a functional cycle that is linked to its ATPase activity. This cycle probably induces conformational changes in the client proteins, thereby causing their activation. Interacts dynamically with various co- chaperones that modulate its substrate recognition, ATPase cycle and chaperone function. Engages with a range of client protein classes via its interact [...] | 0.801 |
ENSPPYP00000017062 | HSPA4 | ENSPPYP00000017062 | ENSPPYP00000017643 | annotation not available | Heat shock 70 kDa protein 4; Belongs to the heat shock protein 70 family. | 0.761 |
ENSPPYP00000017062 | NR3C1 | ENSPPYP00000017062 | ENSPPYP00000017784 | annotation not available | Glucocorticoid receptor; Receptor for glucocorticoids (GC). Has a dual mode of action: as a transcription factor that binds to glucocorticoid response elements (GRE), both for nuclear and mitochondrial DNA, and as a modulator of other transcription factors. Affects inflammatory responses, cellular proliferation and differentiation in target tissues. Involved in chromatin remodeling. Plays a role in rapid mRNA degradation by binding to the 5' UTR of target mRNAs and interacting with PNRC2 in a ligand-dependent manner which recruits the RNA helicase UPF1 and the mRNA-decapping enzyme DCP [...] | 0.871 |
ENSPPYP00000017062 | PGR | ENSPPYP00000017062 | ENSPPYP00000004346 | annotation not available | PGR isoform 1. | 0.587 |
ENSPPYP00000017062 | PTGES3 | ENSPPYP00000017062 | ENSPPYP00000005319 | annotation not available | Prostaglandin E synthase 3; Cytosolic prostaglandin synthase that catalyzes the oxidoreduction of prostaglandin endoperoxide H2 (PGH2) to prostaglandin E2 (PGE2). Molecular chaperone that localizes to genomic response elements in a hormone-dependent manner and disrupts receptor-mediated transcriptional activation, by promoting disassembly of transcriptional regulatory complexes. Facilitates HIF alpha proteins hydroxylation via interaction with EGLN1/PHD2, leading to recruit EGLN1/PHD2 to the HSP90 pathway. | 0.912 |
FKBP4 | DKFZp468G2216 | ENSPPYP00000004732 | ENSPPYP00000022865 | Peptidylprolyl isomerase. | AR isoform 8. | 0.939 |
FKBP4 | ENSPPYP00000017062 | ENSPPYP00000004732 | ENSPPYP00000017062 | Peptidylprolyl isomerase. | annotation not available | 0.763 |
FKBP4 | FKBP5 | ENSPPYP00000004732 | ENSPPYP00000018489 | Peptidylprolyl isomerase. | Peptidyl-prolyl cis-trans isomerase FKBP5; Immunophilin protein with PPIase and co-chaperone activities. Component of unligated steroid receptors heterocomplexes through interaction with heat-shock protein 90 (HSP90). Plays a role in the intracellular trafficking of heterooligomeric forms of steroid hormone receptors maintaining the complex into the cytoplasm when unliganded (By similarity). | 0.967 |
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