Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
SLC26A8Testis anion transporter 1. (969 aa)    
Predicted Functional Partners:
DEFB126
Beta-defensin; Has antibacterial activity; Belongs to the beta-defensin family.
      
 0.729
GALNTL5
GALNTL5 isoform 1.
      
 0.657
MTHFR
Methylenetetrahydrofolate reductase; Belongs to the methylenetetrahydrofolate reductase family.
   
  
 0.635
RACGAP1
Rac GTPase activating protein 1.
    
 
 0.584
MYH13
MYH13 isoform 1; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.
      
 0.569
MYH8
MYH8 isoform 1; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.
      
 0.564
CNOT7
CCR4-NOT transcription complex subunit 7.
      
 0.498
ANLN
ANLN isoform 2.
      
 0.490
CEP57
Centrosomal protein 57.
      
 0.485
SEPTIN4-2
Septin-4; Filament-forming cytoskeletal GTPase. Forms a filamentous structure with SEPTIN12, SEPTIN6, SEPTIN2 and probably SEPTIN4 at the sperm annulus which is required for the structural integrity and motility of the sperm tail during postmeiotic differentiation (By similarity). May play a role in cytokinesis (Potential). May play a role in platelet secretion (By similarity).
      
 0.474
Your Current Organism:
Pongo abelii
NCBI taxonomy Id: 9601
Other names: Orang-utan, Orangutan, P. abelii, Pongo pygmaeus abeli, Pongo pygmaeus abelii, Sumatran orangutan, orang utan
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