Export your current network:
... as a vector graphic:
SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc
... as short tabular text output:
TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)
... as tabular text output:
TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)
... as an XML summary:
structured XML interaction data, according to the 'PSI-MI' data standard
... protein node degrees:
node degree of proteins in your network (given the current score cut-off)
... network coordinates:
a flat-file format describing the coordinates and colors of nodes in the network
... protein sequences:
MFA: multi-fasta format - containing the aminoacid sequences in the network
... protein annotations:
a tab-delimited file describing the names, domains and descriptions of proteins in your network
... functional annotations:
a tab-delimited file containing all known functional terms of proteins in your network
Browse interactions in tabular form:
| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| CDC14A | ENSPPYP00000019690 | ENSPPYP00000001292 | ENSPPYP00000019690 | Cell division cycle 14A. | LOW QUALITY PROTEIN: dual specificity protein phosphatase CDC14C. | 0.930 |
| CDC14A | MOB1A | ENSPPYP00000001292 | ENSPPYP00000013698 | Cell division cycle 14A. | MOB kinase activator 1A; Activator of LATS1/2 in the Hippo signaling pathway which plays a pivotal role in organ size control and tumor suppression by restricting proliferation and promoting apoptosis. The core of this pathway is composed of a kinase cascade wherein STK3/MST2 and STK4/MST1, in complex with its regulatory protein SAV1, phosphorylates and activates LATS1/2 in complex with its regulatory protein MOB1, which in turn phosphorylates and inactivates YAP1 oncoprotein and WWTR1/TAZ. Phosphorylation of YAP1 by LATS1/2 inhibits its translocation into the nucleus to regulate cellu [...] | 0.489 |
| CDC14A | STK38 | ENSPPYP00000001292 | ENSPPYP00000018509 | Cell division cycle 14A. | Serine/threonine-protein kinase 38; Negative regulator of MAP3K1/2 signaling. Converts MAP3K2 from its phosphorylated form to its non-phosphorylated form and inhibits autophosphorylation of MAP3K2 (By similarity). | 0.554 |
| CDC14A | STK38L | ENSPPYP00000001292 | ENSPPYP00000004999 | Cell division cycle 14A. | Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. | 0.554 |
| ENSPPYP00000019690 | CDC14A | ENSPPYP00000019690 | ENSPPYP00000001292 | LOW QUALITY PROTEIN: dual specificity protein phosphatase CDC14C. | Cell division cycle 14A. | 0.930 |
| ENSPPYP00000019690 | MOB1A | ENSPPYP00000019690 | ENSPPYP00000013698 | LOW QUALITY PROTEIN: dual specificity protein phosphatase CDC14C. | MOB kinase activator 1A; Activator of LATS1/2 in the Hippo signaling pathway which plays a pivotal role in organ size control and tumor suppression by restricting proliferation and promoting apoptosis. The core of this pathway is composed of a kinase cascade wherein STK3/MST2 and STK4/MST1, in complex with its regulatory protein SAV1, phosphorylates and activates LATS1/2 in complex with its regulatory protein MOB1, which in turn phosphorylates and inactivates YAP1 oncoprotein and WWTR1/TAZ. Phosphorylation of YAP1 by LATS1/2 inhibits its translocation into the nucleus to regulate cellu [...] | 0.489 |
| ENSPPYP00000019690 | STK38 | ENSPPYP00000019690 | ENSPPYP00000018509 | LOW QUALITY PROTEIN: dual specificity protein phosphatase CDC14C. | Serine/threonine-protein kinase 38; Negative regulator of MAP3K1/2 signaling. Converts MAP3K2 from its phosphorylated form to its non-phosphorylated form and inhibits autophosphorylation of MAP3K2 (By similarity). | 0.554 |
| ENSPPYP00000019690 | STK38L | ENSPPYP00000019690 | ENSPPYP00000004999 | LOW QUALITY PROTEIN: dual specificity protein phosphatase CDC14C. | Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. | 0.554 |
| FRY | STK38 | ENSPPYP00000005993 | ENSPPYP00000018509 | FRY isoform 3. | Serine/threonine-protein kinase 38; Negative regulator of MAP3K1/2 signaling. Converts MAP3K2 from its phosphorylated form to its non-phosphorylated form and inhibits autophosphorylation of MAP3K2 (By similarity). | 0.629 |
| FRY | STK38L | ENSPPYP00000005993 | ENSPPYP00000004999 | FRY isoform 3. | Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. | 0.629 |
| FRYL | STK38 | ENSPPYP00000016444 | ENSPPYP00000018509 | FRYL isoform 1. | Serine/threonine-protein kinase 38; Negative regulator of MAP3K1/2 signaling. Converts MAP3K2 from its phosphorylated form to its non-phosphorylated form and inhibits autophosphorylation of MAP3K2 (By similarity). | 0.712 |
| FRYL | STK38L | ENSPPYP00000016444 | ENSPPYP00000004999 | FRYL isoform 1. | Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. | 0.629 |
| MICAL1 | STK38 | ENSPPYP00000018929 | ENSPPYP00000018509 | MICAL1 isoform 2. | Serine/threonine-protein kinase 38; Negative regulator of MAP3K1/2 signaling. Converts MAP3K2 from its phosphorylated form to its non-phosphorylated form and inhibits autophosphorylation of MAP3K2 (By similarity). | 0.579 |
| MICAL1 | STK38L | ENSPPYP00000018929 | ENSPPYP00000004999 | MICAL1 isoform 2. | Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. | 0.406 |
| MOB1A | CDC14A | ENSPPYP00000013698 | ENSPPYP00000001292 | MOB kinase activator 1A; Activator of LATS1/2 in the Hippo signaling pathway which plays a pivotal role in organ size control and tumor suppression by restricting proliferation and promoting apoptosis. The core of this pathway is composed of a kinase cascade wherein STK3/MST2 and STK4/MST1, in complex with its regulatory protein SAV1, phosphorylates and activates LATS1/2 in complex with its regulatory protein MOB1, which in turn phosphorylates and inactivates YAP1 oncoprotein and WWTR1/TAZ. Phosphorylation of YAP1 by LATS1/2 inhibits its translocation into the nucleus to regulate cellu [...] | Cell division cycle 14A. | 0.489 |
| MOB1A | ENSPPYP00000019690 | ENSPPYP00000013698 | ENSPPYP00000019690 | MOB kinase activator 1A; Activator of LATS1/2 in the Hippo signaling pathway which plays a pivotal role in organ size control and tumor suppression by restricting proliferation and promoting apoptosis. The core of this pathway is composed of a kinase cascade wherein STK3/MST2 and STK4/MST1, in complex with its regulatory protein SAV1, phosphorylates and activates LATS1/2 in complex with its regulatory protein MOB1, which in turn phosphorylates and inactivates YAP1 oncoprotein and WWTR1/TAZ. Phosphorylation of YAP1 by LATS1/2 inhibits its translocation into the nucleus to regulate cellu [...] | LOW QUALITY PROTEIN: dual specificity protein phosphatase CDC14C. | 0.489 |
| MOB1A | MOB1B | ENSPPYP00000013698 | ENSPPYP00000016542 | MOB kinase activator 1A; Activator of LATS1/2 in the Hippo signaling pathway which plays a pivotal role in organ size control and tumor suppression by restricting proliferation and promoting apoptosis. The core of this pathway is composed of a kinase cascade wherein STK3/MST2 and STK4/MST1, in complex with its regulatory protein SAV1, phosphorylates and activates LATS1/2 in complex with its regulatory protein MOB1, which in turn phosphorylates and inactivates YAP1 oncoprotein and WWTR1/TAZ. Phosphorylation of YAP1 by LATS1/2 inhibits its translocation into the nucleus to regulate cellu [...] | MOB kinase activator 1B. | 0.994 |
| MOB1A | MOB2 | ENSPPYP00000013698 | ENSPPYP00000003372 | MOB kinase activator 1A; Activator of LATS1/2 in the Hippo signaling pathway which plays a pivotal role in organ size control and tumor suppression by restricting proliferation and promoting apoptosis. The core of this pathway is composed of a kinase cascade wherein STK3/MST2 and STK4/MST1, in complex with its regulatory protein SAV1, phosphorylates and activates LATS1/2 in complex with its regulatory protein MOB1, which in turn phosphorylates and inactivates YAP1 oncoprotein and WWTR1/TAZ. Phosphorylation of YAP1 by LATS1/2 inhibits its translocation into the nucleus to regulate cellu [...] | MOB kinase activator 2. | 0.419 |
| MOB1A | STK38 | ENSPPYP00000013698 | ENSPPYP00000018509 | MOB kinase activator 1A; Activator of LATS1/2 in the Hippo signaling pathway which plays a pivotal role in organ size control and tumor suppression by restricting proliferation and promoting apoptosis. The core of this pathway is composed of a kinase cascade wherein STK3/MST2 and STK4/MST1, in complex with its regulatory protein SAV1, phosphorylates and activates LATS1/2 in complex with its regulatory protein MOB1, which in turn phosphorylates and inactivates YAP1 oncoprotein and WWTR1/TAZ. Phosphorylation of YAP1 by LATS1/2 inhibits its translocation into the nucleus to regulate cellu [...] | Serine/threonine-protein kinase 38; Negative regulator of MAP3K1/2 signaling. Converts MAP3K2 from its phosphorylated form to its non-phosphorylated form and inhibits autophosphorylation of MAP3K2 (By similarity). | 0.855 |
| MOB1A | STK38L | ENSPPYP00000013698 | ENSPPYP00000004999 | MOB kinase activator 1A; Activator of LATS1/2 in the Hippo signaling pathway which plays a pivotal role in organ size control and tumor suppression by restricting proliferation and promoting apoptosis. The core of this pathway is composed of a kinase cascade wherein STK3/MST2 and STK4/MST1, in complex with its regulatory protein SAV1, phosphorylates and activates LATS1/2 in complex with its regulatory protein MOB1, which in turn phosphorylates and inactivates YAP1 oncoprotein and WWTR1/TAZ. Phosphorylation of YAP1 by LATS1/2 inhibits its translocation into the nucleus to regulate cellu [...] | Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. | 0.959 |
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