STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EYS-2Protein eyes shut homolog; Required to maintain the integrity of photoreceptor cells (By similarity). Specifically required for normal morphology of the photoreceptor ciliary pocket, and might thus facilitate protein trafficking between the photoreceptor inner and outer segments via the transition zone (By similarity). (594 aa)    
Predicted Functional Partners:
ENSPPYP00000018736
annotation not available
 
      0.877
EYS
EYS isoform 3.
 
      0.874
ENSPPYP00000018740
annotation not available
 
     
0.870
ENSPPYP00000018739
annotation not available
 
 
0.771
GNAT2
G protein subunit alpha transducin 2.
    
 0.732
ABCA4
ABCA4 isoform 1.
    
 
 0.727
SLC24A1
SLC24A1 isoform 2; Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family.
      
 0.717
CRYBA1
Crystallin beta A1; Belongs to the beta/gamma-crystallin family.
   
  
 0.688
GJA8
Gap junction protein; One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.
      
 0.685
CR201_G0010354
RPGR isoform 10.
    
 0.684
Your Current Organism:
Pongo abelii
NCBI taxonomy Id: 9601
Other names: Orang-utan, Orangutan, P. abelii, Pongo pygmaeus abeli, Pongo pygmaeus abelii, Sumatran orangutan, orang utan
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.