| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| CHUK | IKBKB | ENSPPYP00000002975 | ENSPPYP00000020804 | CHUK isoform 1. | Inhibitor of nuclear factor kappa B kinase subunit beta. | 0.999 |
| CHUK | IKBKG | ENSPPYP00000002975 | ENSPPYP00000023381 | CHUK isoform 1. | Inhibitor of nuclear factor kappa B kinase regulatory subunit gamma. | 0.999 |
| CHUK | MAP3K7 | ENSPPYP00000002975 | ENSPPYP00000018861 | CHUK isoform 1. | Mitogen-activated protein kinase kinase kinase 7; Serine/threonine kinase which acts as an essential component of the MAP kinase signal transduction pathway. Plays an important role in the cascades of cellular responses evoked by changes in the environment. Mediates signal transduction of TRAF6, various cytokines including interleukin-1 (IL-1), transforming growth factor-beta (TGFB), TGFB-related factors like BMP2 and BMP4, toll-like receptors (TLR), tumor necrosis factor receptor CD40 and B-cell receptor (BCR). Ceramides are also able to activate MAP3K7/TAK1. Once activated, acts as a [...] | 0.997 |
| CHUK | SYNGR1 | ENSPPYP00000002975 | ENSPPYP00000013210 | CHUK isoform 1. | Synaptogyrin-1; May play a role in regulated exocytosis. Modulates the localization of synaptophysin/SYP into synaptic-like microvesicles and may therefore play a role in synaptic-like microvesicle formation and/or maturation (By similarity). Involved in the regulation of short- term and long-term synaptic plasticity (By similarity). Belongs to the synaptogyrin family. | 0.976 |
| CHUK | TAB2 | ENSPPYP00000002975 | ENSPPYP00000019131 | CHUK isoform 1. | TGF-beta activated kinase 1 (MAP3K7) binding protein 2. | 0.976 |
| CHUK | TAB3 | ENSPPYP00000002975 | ENSPPYP00000022623 | CHUK isoform 1. | TAB3 isoform 2. | 0.980 |
| CHUK | TRAF2 | ENSPPYP00000002975 | ENSPPYP00000022191 | CHUK isoform 1. | TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. | 0.996 |
| CHUK | TRAF6 | ENSPPYP00000002975 | ENSPPYP00000003845 | CHUK isoform 1. | TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. | 0.998 |
| IKBKB | CHUK | ENSPPYP00000020804 | ENSPPYP00000002975 | Inhibitor of nuclear factor kappa B kinase subunit beta. | CHUK isoform 1. | 0.999 |
| IKBKB | IKBKG | ENSPPYP00000020804 | ENSPPYP00000023381 | Inhibitor of nuclear factor kappa B kinase subunit beta. | Inhibitor of nuclear factor kappa B kinase regulatory subunit gamma. | 0.999 |
| IKBKB | MAP3K7 | ENSPPYP00000020804 | ENSPPYP00000018861 | Inhibitor of nuclear factor kappa B kinase subunit beta. | Mitogen-activated protein kinase kinase kinase 7; Serine/threonine kinase which acts as an essential component of the MAP kinase signal transduction pathway. Plays an important role in the cascades of cellular responses evoked by changes in the environment. Mediates signal transduction of TRAF6, various cytokines including interleukin-1 (IL-1), transforming growth factor-beta (TGFB), TGFB-related factors like BMP2 and BMP4, toll-like receptors (TLR), tumor necrosis factor receptor CD40 and B-cell receptor (BCR). Ceramides are also able to activate MAP3K7/TAK1. Once activated, acts as a [...] | 0.996 |
| IKBKB | SYNGR1 | ENSPPYP00000020804 | ENSPPYP00000013210 | Inhibitor of nuclear factor kappa B kinase subunit beta. | Synaptogyrin-1; May play a role in regulated exocytosis. Modulates the localization of synaptophysin/SYP into synaptic-like microvesicles and may therefore play a role in synaptic-like microvesicle formation and/or maturation (By similarity). Involved in the regulation of short- term and long-term synaptic plasticity (By similarity). Belongs to the synaptogyrin family. | 0.980 |
| IKBKB | TAB2 | ENSPPYP00000020804 | ENSPPYP00000019131 | Inhibitor of nuclear factor kappa B kinase subunit beta. | TGF-beta activated kinase 1 (MAP3K7) binding protein 2. | 0.977 |
| IKBKB | TAB3 | ENSPPYP00000020804 | ENSPPYP00000022623 | Inhibitor of nuclear factor kappa B kinase subunit beta. | TAB3 isoform 2. | 0.978 |
| IKBKB | TRAF2 | ENSPPYP00000020804 | ENSPPYP00000022191 | Inhibitor of nuclear factor kappa B kinase subunit beta. | TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. | 0.996 |
| IKBKB | TRAF6 | ENSPPYP00000020804 | ENSPPYP00000003845 | Inhibitor of nuclear factor kappa B kinase subunit beta. | TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. | 0.998 |
| IKBKG | CHUK | ENSPPYP00000023381 | ENSPPYP00000002975 | Inhibitor of nuclear factor kappa B kinase regulatory subunit gamma. | CHUK isoform 1. | 0.999 |
| IKBKG | IKBKB | ENSPPYP00000023381 | ENSPPYP00000020804 | Inhibitor of nuclear factor kappa B kinase regulatory subunit gamma. | Inhibitor of nuclear factor kappa B kinase subunit beta. | 0.999 |
| IKBKG | MAP3K7 | ENSPPYP00000023381 | ENSPPYP00000018861 | Inhibitor of nuclear factor kappa B kinase regulatory subunit gamma. | Mitogen-activated protein kinase kinase kinase 7; Serine/threonine kinase which acts as an essential component of the MAP kinase signal transduction pathway. Plays an important role in the cascades of cellular responses evoked by changes in the environment. Mediates signal transduction of TRAF6, various cytokines including interleukin-1 (IL-1), transforming growth factor-beta (TGFB), TGFB-related factors like BMP2 and BMP4, toll-like receptors (TLR), tumor necrosis factor receptor CD40 and B-cell receptor (BCR). Ceramides are also able to activate MAP3K7/TAK1. Once activated, acts as a [...] | 0.997 |
| IKBKG | SYNGR1 | ENSPPYP00000023381 | ENSPPYP00000013210 | Inhibitor of nuclear factor kappa B kinase regulatory subunit gamma. | Synaptogyrin-1; May play a role in regulated exocytosis. Modulates the localization of synaptophysin/SYP into synaptic-like microvesicles and may therefore play a role in synaptic-like microvesicle formation and/or maturation (By similarity). Involved in the regulation of short- term and long-term synaptic plasticity (By similarity). Belongs to the synaptogyrin family. | 0.997 |
