RTN4IP1 protein (Pongo abelii) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

RTN4IP1

RTN4IP1 isoform 1. (396 aa)

Predicted Functional Partners:

RTN4

0.832

ZYX

0.594

HSDL2

0.577

FASN

0.554

PYM1

0.519

ADHFE1

0.483

ACADM

0.473

TMEM126A

0.466

DERA

0.442

ATP5F1D

0.438

Your Current Organism:

Pongo abelii

NCBI taxonomy Id: 9601
Other names: Orang-utan, Orangutan, P. abelii, Pongo pygmaeus abeli, Pongo pygmaeus abelii, Sumatran orangutan, orang utan

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ACADM	ADHFE1	ENSPPYP00000001431	ENSPPYP00000020906	Acyl-CoA dehydrogenase medium chain.	Hydroxyacid-oxoacid transhydrogenase, mitochondrial; Catalyzes the cofactor-independent reversible oxidation of gamma-hydroxybutyrate (GHB) to succinic semialdehyde (SSA) coupled to reduction of 2-ketoglutarate (2-KG) to D-2-hydroxyglutarate (D-2-HG). L-3-hydroxybutyrate (L-3-OHB) is also a substrate for HOT when using 2- KG as hydrogen acceptor, resulting in the formation of D-2-HG (By similarity).	0.418
ACADM	FASN	ENSPPYP00000001431	ENSPPYP00000009843	Acyl-CoA dehydrogenase medium chain.	FASN isoform 1.	0.610
ACADM	HSDL2	ENSPPYP00000001431	ENSPPYP00000021856	Acyl-CoA dehydrogenase medium chain.	Hydroxysteroid dehydrogenase-like protein 2; Has apparently no steroid dehydrogenase activity. Belongs to the short-chain dehydrogenases/reductases (SDR) family.	0.879
ACADM	RTN4IP1	ENSPPYP00000001431	ENSPPYP00000018901	Acyl-CoA dehydrogenase medium chain.	RTN4IP1 isoform 1.	0.473
ADHFE1	ACADM	ENSPPYP00000020906	ENSPPYP00000001431	Hydroxyacid-oxoacid transhydrogenase, mitochondrial; Catalyzes the cofactor-independent reversible oxidation of gamma-hydroxybutyrate (GHB) to succinic semialdehyde (SSA) coupled to reduction of 2-ketoglutarate (2-KG) to D-2-hydroxyglutarate (D-2-HG). L-3-hydroxybutyrate (L-3-OHB) is also a substrate for HOT when using 2- KG as hydrogen acceptor, resulting in the formation of D-2-HG (By similarity).	Acyl-CoA dehydrogenase medium chain.	0.418
ADHFE1	DERA	ENSPPYP00000020906	ENSPPYP00000004950	Hydroxyacid-oxoacid transhydrogenase, mitochondrial; Catalyzes the cofactor-independent reversible oxidation of gamma-hydroxybutyrate (GHB) to succinic semialdehyde (SSA) coupled to reduction of 2-ketoglutarate (2-KG) to D-2-hydroxyglutarate (D-2-HG). L-3-hydroxybutyrate (L-3-OHB) is also a substrate for HOT when using 2- KG as hydrogen acceptor, resulting in the formation of D-2-HG (By similarity).	Deoxyribose-phosphate aldolase.	0.892
ADHFE1	HSDL2	ENSPPYP00000020906	ENSPPYP00000021856	Hydroxyacid-oxoacid transhydrogenase, mitochondrial; Catalyzes the cofactor-independent reversible oxidation of gamma-hydroxybutyrate (GHB) to succinic semialdehyde (SSA) coupled to reduction of 2-ketoglutarate (2-KG) to D-2-hydroxyglutarate (D-2-HG). L-3-hydroxybutyrate (L-3-OHB) is also a substrate for HOT when using 2- KG as hydrogen acceptor, resulting in the formation of D-2-HG (By similarity).	Hydroxysteroid dehydrogenase-like protein 2; Has apparently no steroid dehydrogenase activity. Belongs to the short-chain dehydrogenases/reductases (SDR) family.	0.940
ADHFE1	RTN4IP1	ENSPPYP00000020906	ENSPPYP00000018901	Hydroxyacid-oxoacid transhydrogenase, mitochondrial; Catalyzes the cofactor-independent reversible oxidation of gamma-hydroxybutyrate (GHB) to succinic semialdehyde (SSA) coupled to reduction of 2-ketoglutarate (2-KG) to D-2-hydroxyglutarate (D-2-HG). L-3-hydroxybutyrate (L-3-OHB) is also a substrate for HOT when using 2- KG as hydrogen acceptor, resulting in the formation of D-2-HG (By similarity).	RTN4IP1 isoform 1.	0.483
ATP5F1D	RTN4IP1	ENSPPYP00000023615	ENSPPYP00000018901	ATP5D isoform 1.	RTN4IP1 isoform 1.	0.438
DERA	ADHFE1	ENSPPYP00000004950	ENSPPYP00000020906	Deoxyribose-phosphate aldolase.	Hydroxyacid-oxoacid transhydrogenase, mitochondrial; Catalyzes the cofactor-independent reversible oxidation of gamma-hydroxybutyrate (GHB) to succinic semialdehyde (SSA) coupled to reduction of 2-ketoglutarate (2-KG) to D-2-hydroxyglutarate (D-2-HG). L-3-hydroxybutyrate (L-3-OHB) is also a substrate for HOT when using 2- KG as hydrogen acceptor, resulting in the formation of D-2-HG (By similarity).	0.892
DERA	RTN4IP1	ENSPPYP00000004950	ENSPPYP00000018901	Deoxyribose-phosphate aldolase.	RTN4IP1 isoform 1.	0.442
FASN	ACADM	ENSPPYP00000009843	ENSPPYP00000001431	FASN isoform 1.	Acyl-CoA dehydrogenase medium chain.	0.610
FASN	HSDL2	ENSPPYP00000009843	ENSPPYP00000021856	FASN isoform 1.	Hydroxysteroid dehydrogenase-like protein 2; Has apparently no steroid dehydrogenase activity. Belongs to the short-chain dehydrogenases/reductases (SDR) family.	0.583
FASN	RTN4IP1	ENSPPYP00000009843	ENSPPYP00000018901	FASN isoform 1.	RTN4IP1 isoform 1.	0.554
HSDL2	ACADM	ENSPPYP00000021856	ENSPPYP00000001431	Hydroxysteroid dehydrogenase-like protein 2; Has apparently no steroid dehydrogenase activity. Belongs to the short-chain dehydrogenases/reductases (SDR) family.	Acyl-CoA dehydrogenase medium chain.	0.879
HSDL2	ADHFE1	ENSPPYP00000021856	ENSPPYP00000020906	Hydroxysteroid dehydrogenase-like protein 2; Has apparently no steroid dehydrogenase activity. Belongs to the short-chain dehydrogenases/reductases (SDR) family.	Hydroxyacid-oxoacid transhydrogenase, mitochondrial; Catalyzes the cofactor-independent reversible oxidation of gamma-hydroxybutyrate (GHB) to succinic semialdehyde (SSA) coupled to reduction of 2-ketoglutarate (2-KG) to D-2-hydroxyglutarate (D-2-HG). L-3-hydroxybutyrate (L-3-OHB) is also a substrate for HOT when using 2- KG as hydrogen acceptor, resulting in the formation of D-2-HG (By similarity).	0.940
HSDL2	FASN	ENSPPYP00000021856	ENSPPYP00000009843	Hydroxysteroid dehydrogenase-like protein 2; Has apparently no steroid dehydrogenase activity. Belongs to the short-chain dehydrogenases/reductases (SDR) family.	FASN isoform 1.	0.583
HSDL2	RTN4IP1	ENSPPYP00000021856	ENSPPYP00000018901	Hydroxysteroid dehydrogenase-like protein 2; Has apparently no steroid dehydrogenase activity. Belongs to the short-chain dehydrogenases/reductases (SDR) family.	RTN4IP1 isoform 1.	0.577
PYM1	RTN4IP1	ENSPPYP00000005280	ENSPPYP00000018901	PYM homolog 1, exon junction complex associated factor.	RTN4IP1 isoform 1.	0.519
RTN4	RTN4IP1	ENSPPYP00000013843	ENSPPYP00000018901	Reticulon.	RTN4IP1 isoform 1.	0.832