RFX6 protein (Pongo abelii) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Current Organism:

Pongo abelii

NCBI taxonomy Id: 9601
Other names: Orang-utan, Orangutan, P. abelii, Pongo pygmaeus abeli, Pongo pygmaeus abelii, Sumatran orangutan, orang utan

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structured XML interaction data, according to the 'PSI-MI' data standard

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node degree of proteins in your network (given the current score cut-off)

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a flat-file format describing the coordinates and colors of nodes in the network

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MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
GHRL	INS-IGF2	ENSPPYP00000015270	ENSPPYP00000003393	Ghrelin and obestatin prepropeptide.	INS isoform 4; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.	0.957
GHRL	NEUROG3	ENSPPYP00000015270	ENSPPYP00000002762	Ghrelin and obestatin prepropeptide.	NEUROG3 isoform 1.	0.473
GHRL	PAX4	ENSPPYP00000015270	ENSPPYP00000020158	Ghrelin and obestatin prepropeptide.	PAX4 isoform 1.	0.460
GHRL	PCSK1	ENSPPYP00000015270	ENSPPYP00000017493	Ghrelin and obestatin prepropeptide.	PCSK1 isoform 1; Belongs to the peptidase S8 family.	0.876
GHRL	RFX6	ENSPPYP00000015270	ENSPPYP00000018985	Ghrelin and obestatin prepropeptide.	RFX6 isoform 1.	0.521
INS-IGF2	GHRL	ENSPPYP00000003393	ENSPPYP00000015270	INS isoform 4; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.	Ghrelin and obestatin prepropeptide.	0.957
INS-IGF2	NEUROD1	ENSPPYP00000003393	ENSPPYP00000023725	INS isoform 4; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.	Neurogenic differentiation factor.	0.470
INS-IGF2	NEUROG3	ENSPPYP00000003393	ENSPPYP00000002762	INS isoform 4; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.	NEUROG3 isoform 1.	0.483
INS-IGF2	PAX4	ENSPPYP00000003393	ENSPPYP00000020158	INS isoform 4; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.	PAX4 isoform 1.	0.790
INS-IGF2	PCSK1	ENSPPYP00000003393	ENSPPYP00000017493	INS isoform 4; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.	PCSK1 isoform 1; Belongs to the peptidase S8 family.	0.874
INS-IGF2	PDX1	ENSPPYP00000003393	ENSPPYP00000005967	INS isoform 4; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.	Pancreatic and duodenal homeobox 1.	0.886
INS-IGF2	RFX6	ENSPPYP00000003393	ENSPPYP00000018985	INS isoform 4; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.	RFX6 isoform 1.	0.608
MLXIPL	RFX6	ENSPPYP00000019617	ENSPPYP00000018985	MLXIPL isoform 2.	RFX6 isoform 1.	0.625
NEUROD1	INS-IGF2	ENSPPYP00000023725	ENSPPYP00000003393	Neurogenic differentiation factor.	INS isoform 4; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.	0.470
NEUROD1	NEUROG3	ENSPPYP00000023725	ENSPPYP00000002762	Neurogenic differentiation factor.	NEUROG3 isoform 1.	0.615
NEUROD1	PAX4	ENSPPYP00000023725	ENSPPYP00000020158	Neurogenic differentiation factor.	PAX4 isoform 1.	0.698
NEUROD1	PDX1	ENSPPYP00000023725	ENSPPYP00000005967	Neurogenic differentiation factor.	Pancreatic and duodenal homeobox 1.	0.575
NEUROD1	RFX6	ENSPPYP00000023725	ENSPPYP00000018985	Neurogenic differentiation factor.	RFX6 isoform 1.	0.528
NEUROG3	GHRL	ENSPPYP00000002762	ENSPPYP00000015270	NEUROG3 isoform 1.	Ghrelin and obestatin prepropeptide.	0.473
NEUROG3	INS-IGF2	ENSPPYP00000002762	ENSPPYP00000003393	NEUROG3 isoform 1.	INS isoform 4; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.	0.483