RFX6 protein (Pongo abelii) - STRING interaction network

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

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Gene Fusion

Cooccurrence

Coexpression

Experiments

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[Homology]

Score

RFX6

RFX6 isoform 1. (925 aa)

Predicted Functional Partners:

INS-IGF2

0.715

NEUROG3

0.702

SS18L1

0.655

CCNK

0.622

PDX1

0.609

NKX6-1

0.592

NEUROD1

0.577

NKX6-2

0.570

GCK

0.559

PLAGL1

0.558

Your Current Organism:

Pongo abelii

NCBI taxonomy Id: 9601
Other names: Orang-utan, Orangutan, P. abelii, Pongo pygmaeus abeli, Pongo pygmaeus abelii, Sumatran orangutan, orang utan

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CCNK	RFX6	ENSPPYP00000023827	ENSPPYP00000018985	CCNK isoform 2; Belongs to the cyclin family.	RFX6 isoform 1.	0.622
CCNK	SS18L1	ENSPPYP00000023827	ENSPPYP00000012511	CCNK isoform 2; Belongs to the cyclin family.	SS18L1 isoform 1.	0.504
GCK	INS-IGF2	ENSPPYP00000019722	ENSPPYP00000003393	Phosphotransferase.	INS isoform 4; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.	0.638
GCK	NEUROD1	ENSPPYP00000019722	ENSPPYP00000023725	Phosphotransferase.	Neurogenic differentiation factor.	0.825
GCK	NEUROG3	ENSPPYP00000019722	ENSPPYP00000002762	Phosphotransferase.	NEUROG3 isoform 1.	0.486
GCK	NKX6-1	ENSPPYP00000019722	ENSPPYP00000016639	Phosphotransferase.	NKX6-1 isoform 2.	0.457
GCK	NKX6-2	ENSPPYP00000019722	ENSPPYP00000003247	Phosphotransferase.	NKX6-2 isoform 2.	0.437
GCK	PDX1	ENSPPYP00000019722	ENSPPYP00000005967	Phosphotransferase.	Pancreatic and duodenal homeobox 1.	0.873
GCK	PLAGL1	ENSPPYP00000019722	ENSPPYP00000019112	Phosphotransferase.	PLAG1 like zinc finger 1.	0.405
GCK	RFX6	ENSPPYP00000019722	ENSPPYP00000018985	Phosphotransferase.	RFX6 isoform 1.	0.559
INS-IGF2	GCK	ENSPPYP00000003393	ENSPPYP00000019722	INS isoform 4; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.	Phosphotransferase.	0.638
INS-IGF2	NEUROD1	ENSPPYP00000003393	ENSPPYP00000023725	INS isoform 4; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.	Neurogenic differentiation factor.	0.594
INS-IGF2	NEUROG3	ENSPPYP00000003393	ENSPPYP00000002762	INS isoform 4; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.	NEUROG3 isoform 1.	0.576
INS-IGF2	NKX6-1	ENSPPYP00000003393	ENSPPYP00000016639	INS isoform 4; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.	NKX6-1 isoform 2.	0.540
INS-IGF2	NKX6-2	ENSPPYP00000003393	ENSPPYP00000003247	INS isoform 4; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.	NKX6-2 isoform 2.	0.456
INS-IGF2	PDX1	ENSPPYP00000003393	ENSPPYP00000005967	INS isoform 4; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.	Pancreatic and duodenal homeobox 1.	0.832
INS-IGF2	RFX6	ENSPPYP00000003393	ENSPPYP00000018985	INS isoform 4; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.	RFX6 isoform 1.	0.715
NEUROD1	GCK	ENSPPYP00000023725	ENSPPYP00000019722	Neurogenic differentiation factor.	Phosphotransferase.	0.825
NEUROD1	INS-IGF2	ENSPPYP00000023725	ENSPPYP00000003393	Neurogenic differentiation factor.	INS isoform 4; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.	0.594
NEUROD1	NEUROG3	ENSPPYP00000023725	ENSPPYP00000002762	Neurogenic differentiation factor.	NEUROG3 isoform 1.	0.759