MYB protein (Pongo abelii) - STRING interaction network

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

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second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

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Gene Fusion

Cooccurrence

Coexpression

Experiments

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[Homology]

Score

MYB

MYB isoform 11. (641 aa)

Predicted Functional Partners:

EP300

0.973

CEBPB

0.954

GATA2

0.948

RUNX1

0.940

SPI1

0.935

TAL1

0.923

KMT2A

0.922

FLI1

0.902

SIN3A

0.895

CREBBP

0.874

Your Current Organism:

Pongo abelii

NCBI taxonomy Id: 9601
Other names: Orang-utan, Orangutan, P. abelii, Pongo pygmaeus abeli, Pongo pygmaeus abelii, Sumatran orangutan, orang utan

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CEBPB	CREBBP	ENSPPYP00000012431	ENSPPYP00000007974	CCAAT/enhancer-binding protein.	CREBBP isoform 1.	0.590
CEBPB	EP300	ENSPPYP00000012431	ENSPPYP00000013236	CCAAT/enhancer-binding protein.	EP300 isoform 1.	0.951
CEBPB	GATA2	ENSPPYP00000012431	ENSPPYP00000015026	CCAAT/enhancer-binding protein.	GATA2 isoform 1.	0.538
CEBPB	MYB	ENSPPYP00000012431	ENSPPYP00000019068	CCAAT/enhancer-binding protein.	MYB isoform 11.	0.954
CEBPB	RUNX1	ENSPPYP00000012431	ENSPPYP00000012719	CCAAT/enhancer-binding protein.	Runt-related transcription factor; Forms the heterodimeric complex core-binding factor (CBF) with CBFB. RUNX members modulate the transcription of their target genes through recognizing the core consensus binding sequence 5'- TGTGGT-3', or very rarely, 5'-TGCGGT-3', within their regulatory regions via their runt domain, while CBFB is a non-DNA-binding regulatory subunit that allosterically enhances the sequence-specific DNA-binding capacity of RUNX.	0.945
CEBPB	SIN3A	ENSPPYP00000012431	ENSPPYP00000007556	CCAAT/enhancer-binding protein.	SIN3 transcription regulator family member A.	0.419
CEBPB	SPI1	ENSPPYP00000012431	ENSPPYP00000003793	CCAAT/enhancer-binding protein.	Spi-1 proto-oncogene.	0.647
CEBPB	TAL1	ENSPPYP00000012431	ENSPPYP00000001602	CCAAT/enhancer-binding protein.	TAL1 isoform 1.	0.518
CREBBP	CEBPB	ENSPPYP00000007974	ENSPPYP00000012431	CREBBP isoform 1.	CCAAT/enhancer-binding protein.	0.590
CREBBP	EP300	ENSPPYP00000007974	ENSPPYP00000013236	CREBBP isoform 1.	EP300 isoform 1.	0.996
CREBBP	GATA2	ENSPPYP00000007974	ENSPPYP00000015026	CREBBP isoform 1.	GATA2 isoform 1.	0.582
CREBBP	KMT2A	ENSPPYP00000007974	ENSPPYP00000004505	CREBBP isoform 1.	Histone-lysine N-methyltransferase; Belongs to the class V-like SAM-binding methyltransferase superfamily. Histone-lysine methyltransferase family. TRX/MLL subfamily.	0.893
CREBBP	MYB	ENSPPYP00000007974	ENSPPYP00000019068	CREBBP isoform 1.	MYB isoform 11.	0.874
CREBBP	RUNX1	ENSPPYP00000007974	ENSPPYP00000012719	CREBBP isoform 1.	Runt-related transcription factor; Forms the heterodimeric complex core-binding factor (CBF) with CBFB. RUNX members modulate the transcription of their target genes through recognizing the core consensus binding sequence 5'- TGTGGT-3', or very rarely, 5'-TGCGGT-3', within their regulatory regions via their runt domain, while CBFB is a non-DNA-binding regulatory subunit that allosterically enhances the sequence-specific DNA-binding capacity of RUNX.	0.572
CREBBP	SIN3A	ENSPPYP00000007974	ENSPPYP00000007556	CREBBP isoform 1.	SIN3 transcription regulator family member A.	0.612
EP300	CEBPB	ENSPPYP00000013236	ENSPPYP00000012431	EP300 isoform 1.	CCAAT/enhancer-binding protein.	0.951
EP300	CREBBP	ENSPPYP00000013236	ENSPPYP00000007974	EP300 isoform 1.	CREBBP isoform 1.	0.996
EP300	GATA2	ENSPPYP00000013236	ENSPPYP00000015026	EP300 isoform 1.	GATA2 isoform 1.	0.758
EP300	KMT2A	ENSPPYP00000013236	ENSPPYP00000004505	EP300 isoform 1.	Histone-lysine N-methyltransferase; Belongs to the class V-like SAM-binding methyltransferase superfamily. Histone-lysine methyltransferase family. TRX/MLL subfamily.	0.820
EP300	MYB	ENSPPYP00000013236	ENSPPYP00000019068	EP300 isoform 1.	MYB isoform 11.	0.973