IYD protein (Pongo abelii) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

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empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

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textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Current Organism:

Pongo abelii

NCBI taxonomy Id: 9601
Other names: Orang-utan, Orangutan, P. abelii, Pongo pygmaeus abeli, Pongo pygmaeus abelii, Sumatran orangutan, orang utan

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CR201_G0047127	ENSPPYP00000013231	ENSPPYP00000010712	ENSPPYP00000013231	T0166082 isoform 1.	annotation not available	0.498
CR201_G0047127	FDX1	ENSPPYP00000010712	ENSPPYP00000004413	T0166082 isoform 1.	FDX1 isoform 1.	0.779
CR201_G0047127	IYD	ENSPPYP00000010712	ENSPPYP00000019149	T0166082 isoform 1.	Iodotyrosine deiodinase 1; Catalyzes the oxidative NADPH-dependent deiodination of monoiodotyrosine (L-MIT) or diiodotyrosine (L-DIT). Acts during the hydrolysis of thyroglobulin to liberate iodide, which can then reenter the hormone-producing pathways. Acts more efficiently on monoiodotyrosine than on diiodotyrosine.	0.682
CR201_G0047127	METAP1D	ENSPPYP00000010712	ENSPPYP00000014437	T0166082 isoform 1.	Methionine aminopeptidase; Cotranslationally removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met- Ala-, Cys, Gly, Pro, Ser, Thr, or Val).	0.582
CR201_G0047127	RFK	ENSPPYP00000010712	ENSPPYP00000021623	T0166082 isoform 1.	RFK isoform 3.	0.498
DUOX2	DUOXA2	ENSPPYP00000007295	ENSPPYP00000007296	DUOX2 isoform 1.	Dual oxidase maturation factor 2.	0.999
DUOX2	IYD	ENSPPYP00000007295	ENSPPYP00000019149	DUOX2 isoform 1.	Iodotyrosine deiodinase 1; Catalyzes the oxidative NADPH-dependent deiodination of monoiodotyrosine (L-MIT) or diiodotyrosine (L-DIT). Acts during the hydrolysis of thyroglobulin to liberate iodide, which can then reenter the hormone-producing pathways. Acts more efficiently on monoiodotyrosine than on diiodotyrosine.	0.820
DUOX2	SLC26A4	ENSPPYP00000007295	ENSPPYP00000020068	DUOX2 isoform 1.	Pendrin; Sodium-independent transporter of chloride and iodide. Belongs to the SLC26A/SulP transporter (TC 2.A.53) family.	0.665
DUOXA2	DUOX2	ENSPPYP00000007296	ENSPPYP00000007295	Dual oxidase maturation factor 2.	DUOX2 isoform 1.	0.999
DUOXA2	IYD	ENSPPYP00000007296	ENSPPYP00000019149	Dual oxidase maturation factor 2.	Iodotyrosine deiodinase 1; Catalyzes the oxidative NADPH-dependent deiodination of monoiodotyrosine (L-MIT) or diiodotyrosine (L-DIT). Acts during the hydrolysis of thyroglobulin to liberate iodide, which can then reenter the hormone-producing pathways. Acts more efficiently on monoiodotyrosine than on diiodotyrosine.	0.843
DUOXA2	SLC26A4	ENSPPYP00000007296	ENSPPYP00000020068	Dual oxidase maturation factor 2.	Pendrin; Sodium-independent transporter of chloride and iodide. Belongs to the SLC26A/SulP transporter (TC 2.A.53) family.	0.748
ENSPPYP00000013231	CR201_G0047127	ENSPPYP00000013231	ENSPPYP00000010712	annotation not available	T0166082 isoform 1.	0.498
ENSPPYP00000013231	FDX1	ENSPPYP00000013231	ENSPPYP00000004413	annotation not available	FDX1 isoform 1.	0.498
ENSPPYP00000013231	IYD	ENSPPYP00000013231	ENSPPYP00000019149	annotation not available	Iodotyrosine deiodinase 1; Catalyzes the oxidative NADPH-dependent deiodination of monoiodotyrosine (L-MIT) or diiodotyrosine (L-DIT). Acts during the hydrolysis of thyroglobulin to liberate iodide, which can then reenter the hormone-producing pathways. Acts more efficiently on monoiodotyrosine than on diiodotyrosine.	0.709
ENSPPYP00000013231	METAP1D	ENSPPYP00000013231	ENSPPYP00000014437	annotation not available	Methionine aminopeptidase; Cotranslationally removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met- Ala-, Cys, Gly, Pro, Ser, Thr, or Val).	0.555
FDX1	CR201_G0047127	ENSPPYP00000004413	ENSPPYP00000010712	FDX1 isoform 1.	T0166082 isoform 1.	0.779
FDX1	ENSPPYP00000013231	ENSPPYP00000004413	ENSPPYP00000013231	FDX1 isoform 1.	annotation not available	0.498
FDX1	IYD	ENSPPYP00000004413	ENSPPYP00000019149	FDX1 isoform 1.	Iodotyrosine deiodinase 1; Catalyzes the oxidative NADPH-dependent deiodination of monoiodotyrosine (L-MIT) or diiodotyrosine (L-DIT). Acts during the hydrolysis of thyroglobulin to liberate iodide, which can then reenter the hormone-producing pathways. Acts more efficiently on monoiodotyrosine than on diiodotyrosine.	0.682
FDX1	METAP1D	ENSPPYP00000004413	ENSPPYP00000014437	FDX1 isoform 1.	Methionine aminopeptidase; Cotranslationally removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met- Ala-, Cys, Gly, Pro, Ser, Thr, or Val).	0.582
FDX1	RFK	ENSPPYP00000004413	ENSPPYP00000021623	FDX1 isoform 1.	RFK isoform 3.	0.498