node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ACTB | ACTG1 | ENSPPYP00000019427 | ENSPPYP00000009805 | Actin, cytoplasmic 1, N-terminally processed; Actin is a highly conserved protein that polymerizes to produce filaments that form cross-linked networks in the cytoplasm of cells. Actin exists in both monomeric (G-actin) and polymeric (F-actin) forms, both forms playing key functions, such as cell motility and contraction. In addition to their role in the cytoplasmic cytoskeleton, G- and F-actin also localize in the nucleus, and regulate gene transcription and motility and repair of damaged DNA. | ACTG1 isoform 10. | 0.999 |
ACTB | ACTL6A | ENSPPYP00000019427 | ENSPPYP00000016016 | Actin, cytoplasmic 1, N-terminally processed; Actin is a highly conserved protein that polymerizes to produce filaments that form cross-linked networks in the cytoplasm of cells. Actin exists in both monomeric (G-actin) and polymeric (F-actin) forms, both forms playing key functions, such as cell motility and contraction. In addition to their role in the cytoplasmic cytoskeleton, G- and F-actin also localize in the nucleus, and regulate gene transcription and motility and repair of damaged DNA. | ACTL6A isoform 2; Belongs to the actin family. | 0.999 |
ACTB | ARID1A | ENSPPYP00000019427 | ENSPPYP00000001940 | Actin, cytoplasmic 1, N-terminally processed; Actin is a highly conserved protein that polymerizes to produce filaments that form cross-linked networks in the cytoplasm of cells. Actin exists in both monomeric (G-actin) and polymeric (F-actin) forms, both forms playing key functions, such as cell motility and contraction. In addition to their role in the cytoplasmic cytoskeleton, G- and F-actin also localize in the nucleus, and regulate gene transcription and motility and repair of damaged DNA. | ARID1A isoform 1. | 0.989 |
ACTB | CFL1 | ENSPPYP00000019427 | ENSPPYP00000003525 | Actin, cytoplasmic 1, N-terminally processed; Actin is a highly conserved protein that polymerizes to produce filaments that form cross-linked networks in the cytoplasm of cells. Actin exists in both monomeric (G-actin) and polymeric (F-actin) forms, both forms playing key functions, such as cell motility and contraction. In addition to their role in the cytoplasmic cytoskeleton, G- and F-actin also localize in the nucleus, and regulate gene transcription and motility and repair of damaged DNA. | CFL1 isoform 4; Belongs to the actin-binding proteins ADF family. | 0.996 |
ACTB | CFL2 | ENSPPYP00000019427 | ENSPPYP00000006519 | Actin, cytoplasmic 1, N-terminally processed; Actin is a highly conserved protein that polymerizes to produce filaments that form cross-linked networks in the cytoplasm of cells. Actin exists in both monomeric (G-actin) and polymeric (F-actin) forms, both forms playing key functions, such as cell motility and contraction. In addition to their role in the cytoplasmic cytoskeleton, G- and F-actin also localize in the nucleus, and regulate gene transcription and motility and repair of damaged DNA. | CFL2 isoform 1; Belongs to the actin-binding proteins ADF family. | 0.992 |
ACTB | PFN1 | ENSPPYP00000019427 | ENSPPYP00000008839 | Actin, cytoplasmic 1, N-terminally processed; Actin is a highly conserved protein that polymerizes to produce filaments that form cross-linked networks in the cytoplasm of cells. Actin exists in both monomeric (G-actin) and polymeric (F-actin) forms, both forms playing key functions, such as cell motility and contraction. In addition to their role in the cytoplasmic cytoskeleton, G- and F-actin also localize in the nucleus, and regulate gene transcription and motility and repair of damaged DNA. | Profilin; Belongs to the profilin family. | 0.988 |
ACTB | PFN4 | ENSPPYP00000019427 | ENSPPYP00000014071 | Actin, cytoplasmic 1, N-terminally processed; Actin is a highly conserved protein that polymerizes to produce filaments that form cross-linked networks in the cytoplasm of cells. Actin exists in both monomeric (G-actin) and polymeric (F-actin) forms, both forms playing key functions, such as cell motility and contraction. In addition to their role in the cytoplasmic cytoskeleton, G- and F-actin also localize in the nucleus, and regulate gene transcription and motility and repair of damaged DNA. | Profilin; Belongs to the profilin family. | 0.989 |
ACTB | RUVBL1 | ENSPPYP00000019427 | ENSPPYP00000015029 | Actin, cytoplasmic 1, N-terminally processed; Actin is a highly conserved protein that polymerizes to produce filaments that form cross-linked networks in the cytoplasm of cells. Actin exists in both monomeric (G-actin) and polymeric (F-actin) forms, both forms playing key functions, such as cell motility and contraction. In addition to their role in the cytoplasmic cytoskeleton, G- and F-actin also localize in the nucleus, and regulate gene transcription and motility and repair of damaged DNA. | RuvB-like helicase; Proposed core component of the chromatin remodeling Ino80 complex which exhibits DNA- and nucleosome-activated ATPase activity and catalyzes ATP-dependent nucleosome sliding. | 0.986 |
ACTB | RUVBL2 | ENSPPYP00000019427 | ENSPPYP00000011437 | Actin, cytoplasmic 1, N-terminally processed; Actin is a highly conserved protein that polymerizes to produce filaments that form cross-linked networks in the cytoplasm of cells. Actin exists in both monomeric (G-actin) and polymeric (F-actin) forms, both forms playing key functions, such as cell motility and contraction. In addition to their role in the cytoplasmic cytoskeleton, G- and F-actin also localize in the nucleus, and regulate gene transcription and motility and repair of damaged DNA. | RuvB-like helicase; Proposed core component of the chromatin remodeling Ino80 complex which exhibits DNA- and nucleosome-activated ATPase activity and catalyzes ATP-dependent nucleosome sliding. | 0.990 |
ACTB | SMARCA4 | ENSPPYP00000019427 | ENSPPYP00000010731 | Actin, cytoplasmic 1, N-terminally processed; Actin is a highly conserved protein that polymerizes to produce filaments that form cross-linked networks in the cytoplasm of cells. Actin exists in both monomeric (G-actin) and polymeric (F-actin) forms, both forms playing key functions, such as cell motility and contraction. In addition to their role in the cytoplasmic cytoskeleton, G- and F-actin also localize in the nucleus, and regulate gene transcription and motility and repair of damaged DNA. | SMARCA4 isoform 2. | 0.988 |
ACTG1 | ACTB | ENSPPYP00000009805 | ENSPPYP00000019427 | ACTG1 isoform 10. | Actin, cytoplasmic 1, N-terminally processed; Actin is a highly conserved protein that polymerizes to produce filaments that form cross-linked networks in the cytoplasm of cells. Actin exists in both monomeric (G-actin) and polymeric (F-actin) forms, both forms playing key functions, such as cell motility and contraction. In addition to their role in the cytoplasmic cytoskeleton, G- and F-actin also localize in the nucleus, and regulate gene transcription and motility and repair of damaged DNA. | 0.999 |
ACTG1 | ACTL6A | ENSPPYP00000009805 | ENSPPYP00000016016 | ACTG1 isoform 10. | ACTL6A isoform 2; Belongs to the actin family. | 0.924 |
ACTG1 | ARID1A | ENSPPYP00000009805 | ENSPPYP00000001940 | ACTG1 isoform 10. | ARID1A isoform 1. | 0.868 |
ACTG1 | CFL1 | ENSPPYP00000009805 | ENSPPYP00000003525 | ACTG1 isoform 10. | CFL1 isoform 4; Belongs to the actin-binding proteins ADF family. | 0.991 |
ACTG1 | CFL2 | ENSPPYP00000009805 | ENSPPYP00000006519 | ACTG1 isoform 10. | CFL2 isoform 1; Belongs to the actin-binding proteins ADF family. | 0.989 |
ACTG1 | PFN1 | ENSPPYP00000009805 | ENSPPYP00000008839 | ACTG1 isoform 10. | Profilin; Belongs to the profilin family. | 0.821 |
ACTG1 | PFN4 | ENSPPYP00000009805 | ENSPPYP00000014071 | ACTG1 isoform 10. | Profilin; Belongs to the profilin family. | 0.980 |
ACTG1 | RUVBL1 | ENSPPYP00000009805 | ENSPPYP00000015029 | ACTG1 isoform 10. | RuvB-like helicase; Proposed core component of the chromatin remodeling Ino80 complex which exhibits DNA- and nucleosome-activated ATPase activity and catalyzes ATP-dependent nucleosome sliding. | 0.633 |
ACTG1 | RUVBL2 | ENSPPYP00000009805 | ENSPPYP00000011437 | ACTG1 isoform 10. | RuvB-like helicase; Proposed core component of the chromatin remodeling Ino80 complex which exhibits DNA- and nucleosome-activated ATPase activity and catalyzes ATP-dependent nucleosome sliding. | 0.540 |
ACTG1 | SMARCA4 | ENSPPYP00000009805 | ENSPPYP00000010731 | ACTG1 isoform 10. | SMARCA4 isoform 2. | 0.858 |