Export your current network:
... as a vector graphic:
SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc
... as short tabular text output:
TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)
... as tabular text output:
TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)
... as an XML summary:
structured XML interaction data, according to the 'PSI-MI' data standard
... protein node degrees:
node degree of proteins in your network (given the current score cut-off)
... network coordinates:
a flat-file format describing the coordinates and colors of nodes in the network
... protein sequences:
MFA: multi-fasta format - containing the aminoacid sequences in the network
... protein annotations:
a tab-delimited file describing the names, domains and descriptions of proteins in your network
... functional annotations:
a tab-delimited file containing all known functional terms of proteins in your network
Browse interactions in tabular form:
| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ENSPPYP00000016868 | RUNX2 | ENSPPYP00000016868 | ENSPPYP00000018641 | annotation not available | Runt-related transcription factor; Forms the heterodimeric complex core-binding factor (CBF) with CBFB. RUNX members modulate the transcription of their target genes through recognizing the core consensus binding sequence 5'- TGTGGT-3', or very rarely, 5'-TGCGGT-3', within their regulatory regions via their runt domain, while CBFB is a non-DNA-binding regulatory subunit that allosterically enhances the sequence-specific DNA-binding capacity of RUNX. | 0.618 |
| ENSPPYP00000016868 | SMAD1 | ENSPPYP00000016868 | ENSPPYP00000016869 | annotation not available | Mothers against decapentaplegic homolog. | 0.639 |
| ENSPPYP00000016868 | SMAD3 | ENSPPYP00000016868 | ENSPPYP00000007465 | annotation not available | Mothers against decapentaplegic homolog. | 0.475 |
| ENSPPYP00000016868 | SMAD5 | ENSPPYP00000016868 | ENSPPYP00000017676 | annotation not available | Mothers against decapentaplegic homolog 5; Transcriptional modulator activated by BMP (bone morphogenetic proteins) type 1 receptor kinase. SMAD5 is a receptor- regulated SMAD (R-SMAD) (By similarity). | 0.557 |
| ENSPPYP00000016868 | SMAD6 | ENSPPYP00000016868 | ENSPPYP00000007463 | annotation not available | Mothers against decapentaplegic homolog. | 0.771 |
| ENSPPYP00000016868 | SMAD7 | ENSPPYP00000016868 | ENSPPYP00000010278 | annotation not available | Mothers against decapentaplegic homolog. | 0.467 |
| ENSPPYP00000016868 | SMURF1 | ENSPPYP00000016868 | ENSPPYP00000019458 | annotation not available | E3 ubiquitin-protein ligase. | 0.952 |
| ENSPPYP00000016868 | SMURF2 | ENSPPYP00000016868 | ENSPPYP00000009604 | annotation not available | E3 ubiquitin-protein ligase. | 0.847 |
| PLEKHO1 | SMURF1 | ENSPPYP00000001061 | ENSPPYP00000019458 | Pleckstrin homology domain containing O1. | E3 ubiquitin-protein ligase. | 0.928 |
| PLEKHO1 | SMURF2 | ENSPPYP00000001061 | ENSPPYP00000009604 | Pleckstrin homology domain containing O1. | E3 ubiquitin-protein ligase. | 0.408 |
| RHOA | SMAD3 | ENSPPYP00000015522 | ENSPPYP00000007465 | Transforming protein RhoA; Small GTPase which cycles between an active GTP-bound and an inactive GDP-bound state. Mainly associated with cytoskeleton organization, in active state binds to a variety of effector proteins to regulate cellular responses such cytoskeletal dynamics, cell migration and cell cycle. Regulates a signal transduction pathway linking plasma membrane receptors to the assembly of focal adhesions and actin stress fibers. Involved in a microtubule-dependent signal that is required for the myosin contractile ring formation during cell cycle cytokinesis. Plays an essent [...] | Mothers against decapentaplegic homolog. | 0.408 |
| RHOA | SMURF1 | ENSPPYP00000015522 | ENSPPYP00000019458 | Transforming protein RhoA; Small GTPase which cycles between an active GTP-bound and an inactive GDP-bound state. Mainly associated with cytoskeleton organization, in active state binds to a variety of effector proteins to regulate cellular responses such cytoskeletal dynamics, cell migration and cell cycle. Regulates a signal transduction pathway linking plasma membrane receptors to the assembly of focal adhesions and actin stress fibers. Involved in a microtubule-dependent signal that is required for the myosin contractile ring formation during cell cycle cytokinesis. Plays an essent [...] | E3 ubiquitin-protein ligase. | 0.966 |
| RHOA | SMURF2 | ENSPPYP00000015522 | ENSPPYP00000009604 | Transforming protein RhoA; Small GTPase which cycles between an active GTP-bound and an inactive GDP-bound state. Mainly associated with cytoskeleton organization, in active state binds to a variety of effector proteins to regulate cellular responses such cytoskeletal dynamics, cell migration and cell cycle. Regulates a signal transduction pathway linking plasma membrane receptors to the assembly of focal adhesions and actin stress fibers. Involved in a microtubule-dependent signal that is required for the myosin contractile ring formation during cell cycle cytokinesis. Plays an essent [...] | E3 ubiquitin-protein ligase. | 0.869 |
| RUNX2 | ENSPPYP00000016868 | ENSPPYP00000018641 | ENSPPYP00000016868 | Runt-related transcription factor; Forms the heterodimeric complex core-binding factor (CBF) with CBFB. RUNX members modulate the transcription of their target genes through recognizing the core consensus binding sequence 5'- TGTGGT-3', or very rarely, 5'-TGCGGT-3', within their regulatory regions via their runt domain, while CBFB is a non-DNA-binding regulatory subunit that allosterically enhances the sequence-specific DNA-binding capacity of RUNX. | annotation not available | 0.618 |
| RUNX2 | SMAD1 | ENSPPYP00000018641 | ENSPPYP00000016869 | Runt-related transcription factor; Forms the heterodimeric complex core-binding factor (CBF) with CBFB. RUNX members modulate the transcription of their target genes through recognizing the core consensus binding sequence 5'- TGTGGT-3', or very rarely, 5'-TGCGGT-3', within their regulatory regions via their runt domain, while CBFB is a non-DNA-binding regulatory subunit that allosterically enhances the sequence-specific DNA-binding capacity of RUNX. | Mothers against decapentaplegic homolog. | 0.618 |
| RUNX2 | SMAD3 | ENSPPYP00000018641 | ENSPPYP00000007465 | Runt-related transcription factor; Forms the heterodimeric complex core-binding factor (CBF) with CBFB. RUNX members modulate the transcription of their target genes through recognizing the core consensus binding sequence 5'- TGTGGT-3', or very rarely, 5'-TGCGGT-3', within their regulatory regions via their runt domain, while CBFB is a non-DNA-binding regulatory subunit that allosterically enhances the sequence-specific DNA-binding capacity of RUNX. | Mothers against decapentaplegic homolog. | 0.859 |
| RUNX2 | SMAD5 | ENSPPYP00000018641 | ENSPPYP00000017676 | Runt-related transcription factor; Forms the heterodimeric complex core-binding factor (CBF) with CBFB. RUNX members modulate the transcription of their target genes through recognizing the core consensus binding sequence 5'- TGTGGT-3', or very rarely, 5'-TGCGGT-3', within their regulatory regions via their runt domain, while CBFB is a non-DNA-binding regulatory subunit that allosterically enhances the sequence-specific DNA-binding capacity of RUNX. | Mothers against decapentaplegic homolog 5; Transcriptional modulator activated by BMP (bone morphogenetic proteins) type 1 receptor kinase. SMAD5 is a receptor- regulated SMAD (R-SMAD) (By similarity). | 0.712 |
| RUNX2 | SMAD6 | ENSPPYP00000018641 | ENSPPYP00000007463 | Runt-related transcription factor; Forms the heterodimeric complex core-binding factor (CBF) with CBFB. RUNX members modulate the transcription of their target genes through recognizing the core consensus binding sequence 5'- TGTGGT-3', or very rarely, 5'-TGCGGT-3', within their regulatory regions via their runt domain, while CBFB is a non-DNA-binding regulatory subunit that allosterically enhances the sequence-specific DNA-binding capacity of RUNX. | Mothers against decapentaplegic homolog. | 0.582 |
| RUNX2 | SMAD7 | ENSPPYP00000018641 | ENSPPYP00000010278 | Runt-related transcription factor; Forms the heterodimeric complex core-binding factor (CBF) with CBFB. RUNX members modulate the transcription of their target genes through recognizing the core consensus binding sequence 5'- TGTGGT-3', or very rarely, 5'-TGCGGT-3', within their regulatory regions via their runt domain, while CBFB is a non-DNA-binding regulatory subunit that allosterically enhances the sequence-specific DNA-binding capacity of RUNX. | Mothers against decapentaplegic homolog. | 0.723 |
| RUNX2 | SMURF1 | ENSPPYP00000018641 | ENSPPYP00000019458 | Runt-related transcription factor; Forms the heterodimeric complex core-binding factor (CBF) with CBFB. RUNX members modulate the transcription of their target genes through recognizing the core consensus binding sequence 5'- TGTGGT-3', or very rarely, 5'-TGCGGT-3', within their regulatory regions via their runt domain, while CBFB is a non-DNA-binding regulatory subunit that allosterically enhances the sequence-specific DNA-binding capacity of RUNX. | E3 ubiquitin-protein ligase. | 0.877 |
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