| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ACHE | APP | ENSPPYP00000019545 | ENSPPYP00000012629 | Carboxylic ester hydrolase; Belongs to the type-B carboxylesterase/lipase family. | APP isoform 3. | 0.900 |
| ACHE | CHAT | ENSPPYP00000019545 | ENSPPYP00000002631 | Carboxylic ester hydrolase; Belongs to the type-B carboxylesterase/lipase family. | CHAT isoform 7; Belongs to the carnitine/choline acetyltransferase family. | 0.961 |
| ACHE | CHKA | ENSPPYP00000019545 | ENSPPYP00000003449 | Carboxylic ester hydrolase; Belongs to the type-B carboxylesterase/lipase family. | CHKA isoform 2. | 0.906 |
| ACHE | COLQ | ENSPPYP00000019545 | ENSPPYP00000015760 | Carboxylic ester hydrolase; Belongs to the type-B carboxylesterase/lipase family. | Collagen like tail subunit of asymmetric acetylcholinesterase. | 0.862 |
| ACHE | DOK7 | ENSPPYP00000019545 | ENSPPYP00000016263 | Carboxylic ester hydrolase; Belongs to the type-B carboxylesterase/lipase family. | DOK7 isoform 2. | 0.602 |
| ACHE | GPCPD1 | ENSPPYP00000019545 | ENSPPYP00000011948 | Carboxylic ester hydrolase; Belongs to the type-B carboxylesterase/lipase family. | Glycerophosphocholine phosphodiesterase 1. | 0.910 |
| ACHE | NGF | ENSPPYP00000019545 | ENSPPYP00000001154 | Carboxylic ester hydrolase; Belongs to the type-B carboxylesterase/lipase family. | NGF isoform 1; Belongs to the NGF-beta family. | 0.618 |
| ACHE | PHOSPHO1 | ENSPPYP00000019545 | ENSPPYP00000010006 | Carboxylic ester hydrolase; Belongs to the type-B carboxylesterase/lipase family. | Phosphoethanolamine/phosphocholine phosphatase. | 0.900 |
| ACHE | PNPLA6 | ENSPPYP00000019545 | ENSPPYP00000010625 | Carboxylic ester hydrolase; Belongs to the type-B carboxylesterase/lipase family. | Neuropathy target esterase; Phospholipase B that deacylates intracellular phosphatidylcholine (PtdCho), generating glycerophosphocholine (GroPtdCho). This deacylation occurs at both sn-2 and sn-1 positions of PtdCho. Its specific chemical modification by certain organophosphorus (OP) compounds leads to distal axonopathy (By similarity). | 0.607 |
| ACHE | RGN | ENSPPYP00000019545 | ENSPPYP00000022700 | Carboxylic ester hydrolase; Belongs to the type-B carboxylesterase/lipase family. | Regucalcin; Gluconolactonase with low activity towards other sugar lactones, including gulonolactone and galactonolactone. Can also hydrolyze diisopropyl phosphorofluoridate and phenylacetate (in vitro). Calcium-binding protein. Modulates Ca(2+) signaling, and Ca(2+)- dependent cellular processes and enzyme activities (By similarity). | 0.692 |
| APP | ACHE | ENSPPYP00000012629 | ENSPPYP00000019545 | APP isoform 3. | Carboxylic ester hydrolase; Belongs to the type-B carboxylesterase/lipase family. | 0.900 |
| APP | NGF | ENSPPYP00000012629 | ENSPPYP00000001154 | APP isoform 3. | NGF isoform 1; Belongs to the NGF-beta family. | 0.487 |
| CHAT | ACHE | ENSPPYP00000002631 | ENSPPYP00000019545 | CHAT isoform 7; Belongs to the carnitine/choline acetyltransferase family. | Carboxylic ester hydrolase; Belongs to the type-B carboxylesterase/lipase family. | 0.961 |
| CHAT | CHKA | ENSPPYP00000002631 | ENSPPYP00000003449 | CHAT isoform 7; Belongs to the carnitine/choline acetyltransferase family. | CHKA isoform 2. | 0.911 |
| CHAT | GPCPD1 | ENSPPYP00000002631 | ENSPPYP00000011948 | CHAT isoform 7; Belongs to the carnitine/choline acetyltransferase family. | Glycerophosphocholine phosphodiesterase 1. | 0.921 |
| CHAT | NGF | ENSPPYP00000002631 | ENSPPYP00000001154 | CHAT isoform 7; Belongs to the carnitine/choline acetyltransferase family. | NGF isoform 1; Belongs to the NGF-beta family. | 0.487 |
| CHAT | PHOSPHO1 | ENSPPYP00000002631 | ENSPPYP00000010006 | CHAT isoform 7; Belongs to the carnitine/choline acetyltransferase family. | Phosphoethanolamine/phosphocholine phosphatase. | 0.910 |
| CHKA | ACHE | ENSPPYP00000003449 | ENSPPYP00000019545 | CHKA isoform 2. | Carboxylic ester hydrolase; Belongs to the type-B carboxylesterase/lipase family. | 0.906 |
| CHKA | CHAT | ENSPPYP00000003449 | ENSPPYP00000002631 | CHKA isoform 2. | CHAT isoform 7; Belongs to the carnitine/choline acetyltransferase family. | 0.911 |
| CHKA | GPCPD1 | ENSPPYP00000003449 | ENSPPYP00000011948 | CHKA isoform 2. | Glycerophosphocholine phosphodiesterase 1. | 0.927 |
