| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| DNM1L | FIS1 | ENSPPYP00000005028 | ENSPPYP00000019557 | DNM1L isoform 4; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. | Mitochondrial fission 1 protein; Involved in the fragmentation of the mitochondrial network and its perinuclear clustering. | 0.936 |
| DNM1L | MFF | ENSPPYP00000005028 | ENSPPYP00000014798 | DNM1L isoform 4; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. | MFF isoform 4. | 0.917 |
| DNM1L | MFN2 | ENSPPYP00000005028 | ENSPPYP00000002168 | DNM1L isoform 4; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. | MFN2 isoform 1; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. | 0.809 |
| DNM1L | PEX11A | ENSPPYP00000005028 | ENSPPYP00000007679 | DNM1L isoform 4; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. | PEX11A isoform 3. | 0.604 |
| DNM1L | PEX11B | ENSPPYP00000005028 | ENSPPYP00000001084 | DNM1L isoform 4; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. | Peroxisomal membrane protein 11B; Involved in peroxisomal proliferation. May regulate peroxisome division by recruiting the dynamin-related GTPase DNM1L to the peroxisomal membrane. Promotes membrane protrusion and elongation on the peroxisomal surface. | 0.543 |
| FIS1 | DNM1L | ENSPPYP00000019557 | ENSPPYP00000005028 | Mitochondrial fission 1 protein; Involved in the fragmentation of the mitochondrial network and its perinuclear clustering. | DNM1L isoform 4; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. | 0.936 |
| FIS1 | GDAP1 | ENSPPYP00000019557 | ENSPPYP00000020956 | Mitochondrial fission 1 protein; Involved in the fragmentation of the mitochondrial network and its perinuclear clustering. | GDAP1 isoform 2; Belongs to the GST superfamily. | 0.741 |
| FIS1 | MFF | ENSPPYP00000019557 | ENSPPYP00000014798 | Mitochondrial fission 1 protein; Involved in the fragmentation of the mitochondrial network and its perinuclear clustering. | MFF isoform 4. | 0.740 |
| FIS1 | MFN2 | ENSPPYP00000019557 | ENSPPYP00000002168 | Mitochondrial fission 1 protein; Involved in the fragmentation of the mitochondrial network and its perinuclear clustering. | MFN2 isoform 1; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. | 0.834 |
| FIS1 | OPA1 | ENSPPYP00000019557 | ENSPPYP00000016126 | Mitochondrial fission 1 protein; Involved in the fragmentation of the mitochondrial network and its perinuclear clustering. | Dynamin-like 120 kDa protein, mitochondrial; Dynamin-related GTPase that is essential for normal mitochondrial morphology by regulating the equilibrium between mitochondrial fusion and mitochondrial fission. Binds lipid membranes enriched in negatively charged phospholipids, such as cardiolipin, and promotes membrane tubulation. The intrinsic GTPase activity is low, and is strongly increased by interaction with lipid membranes (By similarity). Plays a role in remodeling cristae and the release of cytochrome c during apoptosis (By similarity). Proteolytic processing in response to intri [...] | 0.768 |
| FIS1 | PEX11A | ENSPPYP00000019557 | ENSPPYP00000007679 | Mitochondrial fission 1 protein; Involved in the fragmentation of the mitochondrial network and its perinuclear clustering. | PEX11A isoform 3. | 0.772 |
| FIS1 | PEX11B | ENSPPYP00000019557 | ENSPPYP00000001084 | Mitochondrial fission 1 protein; Involved in the fragmentation of the mitochondrial network and its perinuclear clustering. | Peroxisomal membrane protein 11B; Involved in peroxisomal proliferation. May regulate peroxisome division by recruiting the dynamin-related GTPase DNM1L to the peroxisomal membrane. Promotes membrane protrusion and elongation on the peroxisomal surface. | 0.763 |
| FIS1 | PEX19 | ENSPPYP00000019557 | ENSPPYP00000000743 | Mitochondrial fission 1 protein; Involved in the fragmentation of the mitochondrial network and its perinuclear clustering. | Peroxisomal biogenesis factor 19; Necessary for early peroxisomal biogenesis. Acts both as a cytosolic chaperone and as an import receptor for peroxisomal membrane proteins (PMPs). Binds and stabilizes newly synthesized PMPs in the cytoplasm by interacting with their hydrophobic membrane-spanning domains, and targets them to the peroxisome membrane by binding to the integral membrane protein PEX3. Excludes CDKN2A from the nucleus and prevents its interaction with MDM2, which results in active degradation of TP53. | 0.719 |
| FIS1 | TBC1D15 | ENSPPYP00000019557 | ENSPPYP00000005441 | Mitochondrial fission 1 protein; Involved in the fragmentation of the mitochondrial network and its perinuclear clustering. | TBC1D15 isoform 2. | 0.960 |
| FIS1 | TBC1D17 | ENSPPYP00000019557 | ENSPPYP00000011494 | Mitochondrial fission 1 protein; Involved in the fragmentation of the mitochondrial network and its perinuclear clustering. | TBC1 domain family member 17. | 0.940 |
| GDAP1 | FIS1 | ENSPPYP00000020956 | ENSPPYP00000019557 | GDAP1 isoform 2; Belongs to the GST superfamily. | Mitochondrial fission 1 protein; Involved in the fragmentation of the mitochondrial network and its perinuclear clustering. | 0.741 |
| GDAP1 | MFN2 | ENSPPYP00000020956 | ENSPPYP00000002168 | GDAP1 isoform 2; Belongs to the GST superfamily. | MFN2 isoform 1; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. | 0.637 |
| GDAP1 | PEX11A | ENSPPYP00000020956 | ENSPPYP00000007679 | GDAP1 isoform 2; Belongs to the GST superfamily. | PEX11A isoform 3. | 0.548 |
| GDAP1 | PEX11B | ENSPPYP00000020956 | ENSPPYP00000001084 | GDAP1 isoform 2; Belongs to the GST superfamily. | Peroxisomal membrane protein 11B; Involved in peroxisomal proliferation. May regulate peroxisome division by recruiting the dynamin-related GTPase DNM1L to the peroxisomal membrane. Promotes membrane protrusion and elongation on the peroxisomal surface. | 0.548 |
| GDAP1 | PEX19 | ENSPPYP00000020956 | ENSPPYP00000000743 | GDAP1 isoform 2; Belongs to the GST superfamily. | Peroxisomal biogenesis factor 19; Necessary for early peroxisomal biogenesis. Acts both as a cytosolic chaperone and as an import receptor for peroxisomal membrane proteins (PMPs). Binds and stabilizes newly synthesized PMPs in the cytoplasm by interacting with their hydrophobic membrane-spanning domains, and targets them to the peroxisome membrane by binding to the integral membrane protein PEX3. Excludes CDKN2A from the nucleus and prevents its interaction with MDM2, which results in active degradation of TP53. | 0.886 |
