STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CUTL1Protein CASP; May be involved in intra-Golgi retrograde transport. (693 aa)    
Predicted Functional Partners:
GOLGA5
GOLGA5 isoform 1.
     
 0.679
EWSR1
EWS RNA binding protein 1.
      
 0.655
TBR1
T-box brain transcription factor 1.
    
 
 0.650
SOX2
SRY-box transcription factor 2.
    
 
 0.624
CCNA1
CCNA1 isoform 3; Belongs to the cyclin family.
    
 
 0.606
CCNA2
CCNA2 isoform 1; Belongs to the cyclin family.
    
 
 0.596
BCL11B
BCL11B isoform 1.
    
 
 0.595
PDGFD
Platelet-derived growth factor D, receptor-binding form; Growth factor that plays an essential role in the regulation of embryonic development, cell proliferation, cell migration, survival and chemotaxis. Potent mitogen for cells of mesenchymal origin. Plays an important role in wound healing. Induces macrophage recruitment, increased interstitial pressure, and blood vessel maturation during angiogenesis. Can initiate events that lead to a mesangial proliferative glomerulonephritis, including influx of monocytes and macrophages and production of extracellular matrix (By similarity).
      
 0.584
SPP2
SPP2 isoform 1.
      
 0.580
SATB2
DNA-binding protein SATB.
    
 
 0.575
Your Current Organism:
Pongo abelii
NCBI taxonomy Id: 9601
Other names: Orang-utan, Orangutan, P. abelii, Pongo pygmaeus abeli, Pongo pygmaeus abelii, Sumatran orangutan, orang utan
Server load: low (28%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.