LAT2 protein (Pongo abelii) - STRING interaction network

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Predicted Interactions

gene neighborhood

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textmining

co-expression

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Score

LAT2

Linker for activation of T cells family member 2. (244 aa)

Predicted Functional Partners:

GRB2

0.870

SYK

0.712

GRAP2

0.705

LCP2

0.696

SOS1

0.694

LYN

0.693

LAT

0.686

PLCG1

0.655

LAX1

0.608

SHC1

0.597

Your Current Organism:

Pongo abelii

NCBI taxonomy Id: 9601
Other names: Orang-utan, Orangutan, P. abelii, Pongo pygmaeus abeli, Pongo pygmaeus abelii, Sumatran orangutan, orang utan

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
GRAP2	GRB2	ENSPPYP00000013217	ENSPPYP00000009686	GRB2 related adaptor protein 2.	Growth factor receptor-bound protein 2; Adapter protein that provides a critical link between cell surface growth factor receptors and the Ras signaling pathway. Belongs to the GRB2/sem-5/DRK family.	0.915
GRAP2	LAT	ENSPPYP00000013217	ENSPPYP00000008163	GRB2 related adaptor protein 2.	LAT isoform 2.	0.998
GRAP2	LAT2	ENSPPYP00000013217	ENSPPYP00000019604	GRB2 related adaptor protein 2.	Linker for activation of T cells family member 2.	0.705
GRAP2	LCP2	ENSPPYP00000013217	ENSPPYP00000017943	GRB2 related adaptor protein 2.	LCP2 isoform 3.	0.999
GRAP2	LYN	ENSPPYP00000013217	ENSPPYP00000020857	GRB2 related adaptor protein 2.	Tyrosine-protein kinase.	0.608
GRAP2	PLCG1	ENSPPYP00000013217	ENSPPYP00000012298	GRB2 related adaptor protein 2.	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades.	0.956
GRAP2	SHC1	ENSPPYP00000013217	ENSPPYP00000000893	GRB2 related adaptor protein 2.	SHC-transforming protein 1; Signaling adapter that couples activated growth factor receptors to signaling pathways. Participates in a signaling cascade initiated by activated KIT and KITLG/SCF. Participates in signaling downstream of the angiopoietin receptor TEK/TIE2, and plays a role in the regulation of endothelial cell migration and sprouting angiogenesis (By similarity).	0.979
GRAP2	SOS1	ENSPPYP00000013217	ENSPPYP00000013933	GRB2 related adaptor protein 2.	SOS1 isoform 2.	0.882
GRAP2	SYK	ENSPPYP00000013217	ENSPPYP00000021701	GRB2 related adaptor protein 2.	Tyrosine-protein kinase.	0.770
GRB2	GRAP2	ENSPPYP00000009686	ENSPPYP00000013217	Growth factor receptor-bound protein 2; Adapter protein that provides a critical link between cell surface growth factor receptors and the Ras signaling pathway. Belongs to the GRB2/sem-5/DRK family.	GRB2 related adaptor protein 2.	0.915
GRB2	LAT	ENSPPYP00000009686	ENSPPYP00000008163	Growth factor receptor-bound protein 2; Adapter protein that provides a critical link between cell surface growth factor receptors and the Ras signaling pathway. Belongs to the GRB2/sem-5/DRK family.	LAT isoform 2.	0.999
GRB2	LAT2	ENSPPYP00000009686	ENSPPYP00000019604	Growth factor receptor-bound protein 2; Adapter protein that provides a critical link between cell surface growth factor receptors and the Ras signaling pathway. Belongs to the GRB2/sem-5/DRK family.	Linker for activation of T cells family member 2.	0.870
GRB2	LAX1	ENSPPYP00000009686	ENSPPYP00000000363	Growth factor receptor-bound protein 2; Adapter protein that provides a critical link between cell surface growth factor receptors and the Ras signaling pathway. Belongs to the GRB2/sem-5/DRK family.	LAX1 isoform 1.	0.626
GRB2	LCP2	ENSPPYP00000009686	ENSPPYP00000017943	Growth factor receptor-bound protein 2; Adapter protein that provides a critical link between cell surface growth factor receptors and the Ras signaling pathway. Belongs to the GRB2/sem-5/DRK family.	LCP2 isoform 3.	0.999
GRB2	LYN	ENSPPYP00000009686	ENSPPYP00000020857	Growth factor receptor-bound protein 2; Adapter protein that provides a critical link between cell surface growth factor receptors and the Ras signaling pathway. Belongs to the GRB2/sem-5/DRK family.	Tyrosine-protein kinase.	0.813
GRB2	PLCG1	ENSPPYP00000009686	ENSPPYP00000012298	Growth factor receptor-bound protein 2; Adapter protein that provides a critical link between cell surface growth factor receptors and the Ras signaling pathway. Belongs to the GRB2/sem-5/DRK family.	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades.	0.987
GRB2	SHC1	ENSPPYP00000009686	ENSPPYP00000000893	Growth factor receptor-bound protein 2; Adapter protein that provides a critical link between cell surface growth factor receptors and the Ras signaling pathway. Belongs to the GRB2/sem-5/DRK family.	SHC-transforming protein 1; Signaling adapter that couples activated growth factor receptors to signaling pathways. Participates in a signaling cascade initiated by activated KIT and KITLG/SCF. Participates in signaling downstream of the angiopoietin receptor TEK/TIE2, and plays a role in the regulation of endothelial cell migration and sprouting angiogenesis (By similarity).	0.999
GRB2	SOS1	ENSPPYP00000009686	ENSPPYP00000013933	Growth factor receptor-bound protein 2; Adapter protein that provides a critical link between cell surface growth factor receptors and the Ras signaling pathway. Belongs to the GRB2/sem-5/DRK family.	SOS1 isoform 2.	0.999
GRB2	SYK	ENSPPYP00000009686	ENSPPYP00000021701	Growth factor receptor-bound protein 2; Adapter protein that provides a critical link between cell surface growth factor receptors and the Ras signaling pathway. Belongs to the GRB2/sem-5/DRK family.	Tyrosine-protein kinase.	0.886
LAT	GRAP2	ENSPPYP00000008163	ENSPPYP00000013217	LAT isoform 2.	GRB2 related adaptor protein 2.	0.998