| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| FZD9 | LRP6 | ENSPPYP00000019620 | ENSPPYP00000024153 | Frizzled class receptor 9; Belongs to the G-protein coupled receptor Fz/Smo family. | Low-density lipoprotein receptor-related protein; Component of the Wnt-Fzd-LRP5-LRP6 complex that triggers beta-catenin signaling through inducing aggregation of receptor-ligand complexes into ribosome-sized signalsomes. Belongs to the LDLR family. | 0.951 |
| FZD9 | RNF43 | ENSPPYP00000019620 | ENSPPYP00000009250 | Frizzled class receptor 9; Belongs to the G-protein coupled receptor Fz/Smo family. | RNF43 isoform 2. | 0.956 |
| FZD9 | ROR1 | ENSPPYP00000019620 | ENSPPYP00000001486 | Frizzled class receptor 9; Belongs to the G-protein coupled receptor Fz/Smo family. | Receptor tyrosine kinase like orphan receptor 1; Belongs to the protein kinase superfamily. Tyr protein kinase family. ROR subfamily. | 0.950 |
| FZD9 | ROR2 | ENSPPYP00000019620 | ENSPPYP00000021705 | Frizzled class receptor 9; Belongs to the G-protein coupled receptor Fz/Smo family. | Receptor tyrosine kinase like orphan receptor 2; Belongs to the protein kinase superfamily. Tyr protein kinase family. ROR subfamily. | 0.950 |
| FZD9 | WNT1 | ENSPPYP00000019620 | ENSPPYP00000005109 | Frizzled class receptor 9; Belongs to the G-protein coupled receptor Fz/Smo family. | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. | 0.983 |
| FZD9 | WNT11 | ENSPPYP00000019620 | ENSPPYP00000004224 | Frizzled class receptor 9; Belongs to the G-protein coupled receptor Fz/Smo family. | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. | 0.985 |
| FZD9 | WNT3A | ENSPPYP00000019620 | ENSPPYP00000000148 | Frizzled class receptor 9; Belongs to the G-protein coupled receptor Fz/Smo family. | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. | 0.967 |
| FZD9 | WNT5A | ENSPPYP00000019620 | ENSPPYP00000015420 | Frizzled class receptor 9; Belongs to the G-protein coupled receptor Fz/Smo family. | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. | 0.992 |
| FZD9 | WNT5B | ENSPPYP00000019620 | ENSPPYP00000004719 | Frizzled class receptor 9; Belongs to the G-protein coupled receptor Fz/Smo family. | Protein Wnt-5b; Ligand for members of the frizzled family of seven transmembrane receptors. Probable developmental protein. May be a signaling molecule which affects the development of discrete regions of tissues. Is likely to signal over only few cell diameters (By similarity); Belongs to the Wnt family. | 0.972 |
| FZD9 | ZNRF3 | ENSPPYP00000019620 | ENSPPYP00000013028 | Frizzled class receptor 9; Belongs to the G-protein coupled receptor Fz/Smo family. | ZNRF3 isoform 2. | 0.948 |
| LRP6 | FZD9 | ENSPPYP00000024153 | ENSPPYP00000019620 | Low-density lipoprotein receptor-related protein; Component of the Wnt-Fzd-LRP5-LRP6 complex that triggers beta-catenin signaling through inducing aggregation of receptor-ligand complexes into ribosome-sized signalsomes. Belongs to the LDLR family. | Frizzled class receptor 9; Belongs to the G-protein coupled receptor Fz/Smo family. | 0.951 |
| LRP6 | RNF43 | ENSPPYP00000024153 | ENSPPYP00000009250 | Low-density lipoprotein receptor-related protein; Component of the Wnt-Fzd-LRP5-LRP6 complex that triggers beta-catenin signaling through inducing aggregation of receptor-ligand complexes into ribosome-sized signalsomes. Belongs to the LDLR family. | RNF43 isoform 2. | 0.732 |
| LRP6 | WNT1 | ENSPPYP00000024153 | ENSPPYP00000005109 | Low-density lipoprotein receptor-related protein; Component of the Wnt-Fzd-LRP5-LRP6 complex that triggers beta-catenin signaling through inducing aggregation of receptor-ligand complexes into ribosome-sized signalsomes. Belongs to the LDLR family. | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. | 0.994 |
| LRP6 | WNT11 | ENSPPYP00000024153 | ENSPPYP00000004224 | Low-density lipoprotein receptor-related protein; Component of the Wnt-Fzd-LRP5-LRP6 complex that triggers beta-catenin signaling through inducing aggregation of receptor-ligand complexes into ribosome-sized signalsomes. Belongs to the LDLR family. | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. | 0.963 |
| LRP6 | WNT3A | ENSPPYP00000024153 | ENSPPYP00000000148 | Low-density lipoprotein receptor-related protein; Component of the Wnt-Fzd-LRP5-LRP6 complex that triggers beta-catenin signaling through inducing aggregation of receptor-ligand complexes into ribosome-sized signalsomes. Belongs to the LDLR family. | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. | 0.997 |
| LRP6 | WNT5A | ENSPPYP00000024153 | ENSPPYP00000015420 | Low-density lipoprotein receptor-related protein; Component of the Wnt-Fzd-LRP5-LRP6 complex that triggers beta-catenin signaling through inducing aggregation of receptor-ligand complexes into ribosome-sized signalsomes. Belongs to the LDLR family. | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. | 0.989 |
| LRP6 | WNT5B | ENSPPYP00000024153 | ENSPPYP00000004719 | Low-density lipoprotein receptor-related protein; Component of the Wnt-Fzd-LRP5-LRP6 complex that triggers beta-catenin signaling through inducing aggregation of receptor-ligand complexes into ribosome-sized signalsomes. Belongs to the LDLR family. | Protein Wnt-5b; Ligand for members of the frizzled family of seven transmembrane receptors. Probable developmental protein. May be a signaling molecule which affects the development of discrete regions of tissues. Is likely to signal over only few cell diameters (By similarity); Belongs to the Wnt family. | 0.980 |
| LRP6 | ZNRF3 | ENSPPYP00000024153 | ENSPPYP00000013028 | Low-density lipoprotein receptor-related protein; Component of the Wnt-Fzd-LRP5-LRP6 complex that triggers beta-catenin signaling through inducing aggregation of receptor-ligand complexes into ribosome-sized signalsomes. Belongs to the LDLR family. | ZNRF3 isoform 2. | 0.905 |
| RNF43 | FZD9 | ENSPPYP00000009250 | ENSPPYP00000019620 | RNF43 isoform 2. | Frizzled class receptor 9; Belongs to the G-protein coupled receptor Fz/Smo family. | 0.956 |
| RNF43 | LRP6 | ENSPPYP00000009250 | ENSPPYP00000024153 | RNF43 isoform 2. | Low-density lipoprotein receptor-related protein; Component of the Wnt-Fzd-LRP5-LRP6 complex that triggers beta-catenin signaling through inducing aggregation of receptor-ligand complexes into ribosome-sized signalsomes. Belongs to the LDLR family. | 0.732 |
