STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
RABGEF1RABGEF1 isoform 2. (544 aa)    
Predicted Functional Partners:
RABEP1
Rabaptin, RAB GTPase binding effector protein 1.
   
 0.999
RABEP2
Rab GTPase-binding effector protein 2; Plays a role in membrane trafficking and in homotypic early endosome fusion. Participates in arteriogenesis by regulating vascular endothelial growth factor receptor 2/VEGFR2 cell surface expression and endosomal trafficking. By interacting with SDCCAG8, localizes to centrosomes and plays a critical role in ciliogenesis.
   
 0.995
RAB5A
RAB5A, member RAS oncogene family.
   
 0.995
RAB22A
RAB22A, member RAS oncogene family.
   
 0.963
GGA1
GGA1 isoform 1.
    
 0.963
ALS2
ALS2 isoform 1.
   
 0.947
RAB20
RAB20, member RAS oncogene family.
   
 0.937
UBC
UBC isoform 2.
    
 0.931
CR201_G0034261
GGA2 isoform 1.
    
 0.927
RAB17
RAB17 isoform 2.
   
 0.923
Your Current Organism:
Pongo abelii
NCBI taxonomy Id: 9601
Other names: Orang-utan, Orangutan, P. abelii, Pongo pygmaeus abeli, Pongo pygmaeus abelii, Sumatran orangutan, orang utan
Server load: medium (50%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.