DDC protein (Pongo abelii) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Current Organism:

Pongo abelii

NCBI taxonomy Id: 9601
Other names: Orang-utan, Orangutan, P. abelii, Pongo pygmaeus abeli, Pongo pygmaeus abelii, Sumatran orangutan, orang utan

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structured XML interaction data, according to the 'PSI-MI' data standard

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AANAT	DDC	ENSPPYP00000009726	ENSPPYP00000019680	AANAT isoform 2.	DDC isoform 1.	0.950
AANAT	IDO1	ENSPPYP00000009726	ENSPPYP00000020785	AANAT isoform 2.	IDO1 isoform 1.	0.921
AANAT	MAOA	ENSPPYP00000009726	ENSPPYP00000022677	AANAT isoform 2.	Amine oxidase [flavin-containing] A; Catalyzes the oxidative deamination of biogenic and xenobiotic amines and has important functions in the metabolism of neuroactive and vasoactive amines in the central nervous system and peripheral tissues. MAOA preferentially oxidizes biogenic amines such as 5-hydroxytryptamine (5-HT), norepinephrine and epinephrine (By similarity).	0.918
AANAT	MAOB	ENSPPYP00000009726	ENSPPYP00000022680	AANAT isoform 2.	Amine oxidase [flavin-containing] B; Catalyzes the oxidative deamination of biogenic and xenobiotic amines and has important functions in the metabolism of neuroactive and vasoactive amines in the central nervous system and peripheral tissues. MAOB preferentially degrades benzylamine and phenylethylamine (By similarity).	0.916
AANAT	TPH1	ENSPPYP00000009726	ENSPPYP00000003958	AANAT isoform 2.	Tryptophan hydroxylase 1.	0.746
AANAT	TPH2	ENSPPYP00000009726	ENSPPYP00000005442	AANAT isoform 2.	Tryptophan hydroxylase 2.	0.610
COMT	DBH	ENSPPYP00000012926	ENSPPYP00000022139	Catechol O-methyltransferase; Catalyzes the O-methylation, and thereby the inactivation, of catecholamine neurotransmitters and catechol hormones.	DBH isoform 1.	0.950
COMT	DDC	ENSPPYP00000012926	ENSPPYP00000019680	Catechol O-methyltransferase; Catalyzes the O-methylation, and thereby the inactivation, of catecholamine neurotransmitters and catechol hormones.	DDC isoform 1.	0.951
COMT	MAOA	ENSPPYP00000012926	ENSPPYP00000022677	Catechol O-methyltransferase; Catalyzes the O-methylation, and thereby the inactivation, of catecholamine neurotransmitters and catechol hormones.	Amine oxidase [flavin-containing] A; Catalyzes the oxidative deamination of biogenic and xenobiotic amines and has important functions in the metabolism of neuroactive and vasoactive amines in the central nervous system and peripheral tissues. MAOA preferentially oxidizes biogenic amines such as 5-hydroxytryptamine (5-HT), norepinephrine and epinephrine (By similarity).	0.978
COMT	MAOB	ENSPPYP00000012926	ENSPPYP00000022680	Catechol O-methyltransferase; Catalyzes the O-methylation, and thereby the inactivation, of catecholamine neurotransmitters and catechol hormones.	Amine oxidase [flavin-containing] B; Catalyzes the oxidative deamination of biogenic and xenobiotic amines and has important functions in the metabolism of neuroactive and vasoactive amines in the central nervous system and peripheral tissues. MAOB preferentially degrades benzylamine and phenylethylamine (By similarity).	0.973
COMT	TH	ENSPPYP00000012926	ENSPPYP00000003395	Catechol O-methyltransferase; Catalyzes the O-methylation, and thereby the inactivation, of catecholamine neurotransmitters and catechol hormones.	TH isoform 6.	0.513
DBH	COMT	ENSPPYP00000022139	ENSPPYP00000012926	DBH isoform 1.	Catechol O-methyltransferase; Catalyzes the O-methylation, and thereby the inactivation, of catecholamine neurotransmitters and catechol hormones.	0.950
DBH	DDC	ENSPPYP00000022139	ENSPPYP00000019680	DBH isoform 1.	DDC isoform 1.	0.959
DBH	MAOA	ENSPPYP00000022139	ENSPPYP00000022677	DBH isoform 1.	Amine oxidase [flavin-containing] A; Catalyzes the oxidative deamination of biogenic and xenobiotic amines and has important functions in the metabolism of neuroactive and vasoactive amines in the central nervous system and peripheral tissues. MAOA preferentially oxidizes biogenic amines such as 5-hydroxytryptamine (5-HT), norepinephrine and epinephrine (By similarity).	0.959
DBH	MAOB	ENSPPYP00000022139	ENSPPYP00000022680	DBH isoform 1.	Amine oxidase [flavin-containing] B; Catalyzes the oxidative deamination of biogenic and xenobiotic amines and has important functions in the metabolism of neuroactive and vasoactive amines in the central nervous system and peripheral tissues. MAOB preferentially degrades benzylamine and phenylethylamine (By similarity).	0.958
DBH	PAH	ENSPPYP00000022139	ENSPPYP00000005573	DBH isoform 1.	Phenylalanine hydroxylase.	0.695
DBH	TH	ENSPPYP00000022139	ENSPPYP00000003395	DBH isoform 1.	TH isoform 6.	0.754
DDC	AANAT	ENSPPYP00000019680	ENSPPYP00000009726	DDC isoform 1.	AANAT isoform 2.	0.950
DDC	COMT	ENSPPYP00000019680	ENSPPYP00000012926	DDC isoform 1.	Catechol O-methyltransferase; Catalyzes the O-methylation, and thereby the inactivation, of catecholamine neurotransmitters and catechol hormones.	0.951
DDC	DBH	ENSPPYP00000019680	ENSPPYP00000022139	DDC isoform 1.	DBH isoform 1.	0.959