Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
AVL9Late secretory pathway protein AVL9 homolog; Functions in cell migration; Belongs to the AVL9 family. (648 aa)    
Predicted Functional Partners:
RIC1
RIC1 isoform 3.
      
 0.730
RAB30
RAB30, member RAS oncogene family.
      
 0.728
DENND11
KIAA1147 isoform 1.
      
 0.716
DENND10
FAM45A isoform 2.
      
 0.713
RAB33B
Ras-related protein Rab-33B; Protein transport. Acts, in coordination with RAB6A, to regulate intra-Golgi retrograde trafficking (By similarity). It is involved in autophagy, acting as a modulator of autophagosome formation (By similarity); Belongs to the small GTPase superfamily. Rab family.
      
 0.689
DENND6A
DENND6A isoform 1.
      
 0.666
RAB33A
RAB33A, member RAS oncogene family.
      
 0.637
DENND2A
DENND2A isoform 4.
      
 0.586
DENND1C
DENND1C isoform 1.
      
 0.580
DENND4B
DENND4B isoform 2.
      
 0.532
Your Current Organism:
Pongo abelii
NCBI taxonomy Id: 9601
Other names: Orang-utan, Orangutan, P. abelii, Pongo pygmaeus abeli, Pongo pygmaeus abelii, Sumatran orangutan, orang utan
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