| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| C17H17orf75 | CIAO1 | ENSPPYP00000009172 | ENSPPYP00000013454 | C17orf75 isoform 2. | Probable cytosolic iron-sulfur protein assembly protein CIAO1; Key component of the cytosolic iron-sulfur protein assembly (CIA) complex, a multiprotein complex that mediates the incorporation of iron-sulfur cluster into extramitochondrial Fe/S proteins. Seems to specifically modulate the transactivation activity of WT1. As part of the mitotic spindle-associated MMXD complex it may play a role in chromosome segregation; Belongs to the WD repeat CIA1 family. | 0.887 |
| C17H17orf75 | CYP20A1 | ENSPPYP00000009172 | ENSPPYP00000014631 | C17orf75 isoform 2. | Cytochrome P450 family 20 subfamily A member 1. | 0.874 |
| C17H17orf75 | DCAF10 | ENSPPYP00000009172 | ENSPPYP00000021355 | C17orf75 isoform 2. | DCAF10 isoform 2. | 0.888 |
| C17H17orf75 | FBLIM1 | ENSPPYP00000009172 | ENSPPYP00000002131 | C17orf75 isoform 2. | Filamin-binding LIM protein 1; Serves as an anchoring site for cell-ECM adhesion proteins and filamin-containing actin filaments. Is implicated in cell shape modulation (spreading) and motility. May participate in the regulation of filamin-mediated cross-linking and stabilization of actin filaments. May also regulate the assembly of filamin-containing signaling complexes that control actin assembly. Promotes dissociation of FLNA from ITGB3 and ITGB7. Promotes activation of integrins and regulates integrin-mediated cell-cell adhesion (By similarity). | 0.764 |
| C17H17orf75 | FKBP14 | ENSPPYP00000009172 | ENSPPYP00000019820 | C17orf75 isoform 2. | Peptidyl-prolyl cis-trans isomerase FKBP14; PPIase which accelerates the folding of proteins during protein synthesis. Has a preference for substrates containing 4- hydroxylproline modifications, including type III collagen. May also target type VI and type X collagens. | 0.585 |
| C17H17orf75 | RAB3IP | ENSPPYP00000009172 | ENSPPYP00000005426 | C17orf75 isoform 2. | T0046992 isoform 1. | 0.926 |
| C17H17orf75 | SYNJ2BP | ENSPPYP00000009172 | ENSPPYP00000023927 | C17orf75 isoform 2. | SYNJ2BP-COX16 isoform 3. | 0.709 |
| CIAO1 | C17H17orf75 | ENSPPYP00000013454 | ENSPPYP00000009172 | Probable cytosolic iron-sulfur protein assembly protein CIAO1; Key component of the cytosolic iron-sulfur protein assembly (CIA) complex, a multiprotein complex that mediates the incorporation of iron-sulfur cluster into extramitochondrial Fe/S proteins. Seems to specifically modulate the transactivation activity of WT1. As part of the mitotic spindle-associated MMXD complex it may play a role in chromosome segregation; Belongs to the WD repeat CIA1 family. | C17orf75 isoform 2. | 0.887 |
| CIAO1 | CYP20A1 | ENSPPYP00000013454 | ENSPPYP00000014631 | Probable cytosolic iron-sulfur protein assembly protein CIAO1; Key component of the cytosolic iron-sulfur protein assembly (CIA) complex, a multiprotein complex that mediates the incorporation of iron-sulfur cluster into extramitochondrial Fe/S proteins. Seems to specifically modulate the transactivation activity of WT1. As part of the mitotic spindle-associated MMXD complex it may play a role in chromosome segregation; Belongs to the WD repeat CIA1 family. | Cytochrome P450 family 20 subfamily A member 1. | 0.827 |
| CIAO1 | DCAF10 | ENSPPYP00000013454 | ENSPPYP00000021355 | Probable cytosolic iron-sulfur protein assembly protein CIAO1; Key component of the cytosolic iron-sulfur protein assembly (CIA) complex, a multiprotein complex that mediates the incorporation of iron-sulfur cluster into extramitochondrial Fe/S proteins. Seems to specifically modulate the transactivation activity of WT1. As part of the mitotic spindle-associated MMXD complex it may play a role in chromosome segregation; Belongs to the WD repeat CIA1 family. | DCAF10 isoform 2. | 0.869 |
| CIAO1 | FBLIM1 | ENSPPYP00000013454 | ENSPPYP00000002131 | Probable cytosolic iron-sulfur protein assembly protein CIAO1; Key component of the cytosolic iron-sulfur protein assembly (CIA) complex, a multiprotein complex that mediates the incorporation of iron-sulfur cluster into extramitochondrial Fe/S proteins. Seems to specifically modulate the transactivation activity of WT1. As part of the mitotic spindle-associated MMXD complex it may play a role in chromosome segregation; Belongs to the WD repeat CIA1 family. | Filamin-binding LIM protein 1; Serves as an anchoring site for cell-ECM adhesion proteins and filamin-containing actin filaments. Is implicated in cell shape modulation (spreading) and motility. May participate in the regulation of filamin-mediated cross-linking and stabilization of actin filaments. May also regulate the assembly of filamin-containing signaling complexes that control actin assembly. Promotes dissociation of FLNA from ITGB3 and ITGB7. Promotes activation of integrins and regulates integrin-mediated cell-cell adhesion (By similarity). | 0.754 |
| CIAO1 | FKBP14 | ENSPPYP00000013454 | ENSPPYP00000019820 | Probable cytosolic iron-sulfur protein assembly protein CIAO1; Key component of the cytosolic iron-sulfur protein assembly (CIA) complex, a multiprotein complex that mediates the incorporation of iron-sulfur cluster into extramitochondrial Fe/S proteins. Seems to specifically modulate the transactivation activity of WT1. As part of the mitotic spindle-associated MMXD complex it may play a role in chromosome segregation; Belongs to the WD repeat CIA1 family. | Peptidyl-prolyl cis-trans isomerase FKBP14; PPIase which accelerates the folding of proteins during protein synthesis. Has a preference for substrates containing 4- hydroxylproline modifications, including type III collagen. May also target type VI and type X collagens. | 0.522 |
| CIAO1 | RAB3IP | ENSPPYP00000013454 | ENSPPYP00000005426 | Probable cytosolic iron-sulfur protein assembly protein CIAO1; Key component of the cytosolic iron-sulfur protein assembly (CIA) complex, a multiprotein complex that mediates the incorporation of iron-sulfur cluster into extramitochondrial Fe/S proteins. Seems to specifically modulate the transactivation activity of WT1. As part of the mitotic spindle-associated MMXD complex it may play a role in chromosome segregation; Belongs to the WD repeat CIA1 family. | T0046992 isoform 1. | 0.888 |
| CIAO1 | SYNJ2BP | ENSPPYP00000013454 | ENSPPYP00000023927 | Probable cytosolic iron-sulfur protein assembly protein CIAO1; Key component of the cytosolic iron-sulfur protein assembly (CIA) complex, a multiprotein complex that mediates the incorporation of iron-sulfur cluster into extramitochondrial Fe/S proteins. Seems to specifically modulate the transactivation activity of WT1. As part of the mitotic spindle-associated MMXD complex it may play a role in chromosome segregation; Belongs to the WD repeat CIA1 family. | SYNJ2BP-COX16 isoform 3. | 0.668 |
| CYP20A1 | C17H17orf75 | ENSPPYP00000014631 | ENSPPYP00000009172 | Cytochrome P450 family 20 subfamily A member 1. | C17orf75 isoform 2. | 0.874 |
| CYP20A1 | CIAO1 | ENSPPYP00000014631 | ENSPPYP00000013454 | Cytochrome P450 family 20 subfamily A member 1. | Probable cytosolic iron-sulfur protein assembly protein CIAO1; Key component of the cytosolic iron-sulfur protein assembly (CIA) complex, a multiprotein complex that mediates the incorporation of iron-sulfur cluster into extramitochondrial Fe/S proteins. Seems to specifically modulate the transactivation activity of WT1. As part of the mitotic spindle-associated MMXD complex it may play a role in chromosome segregation; Belongs to the WD repeat CIA1 family. | 0.827 |
| CYP20A1 | DCAF10 | ENSPPYP00000014631 | ENSPPYP00000021355 | Cytochrome P450 family 20 subfamily A member 1. | DCAF10 isoform 2. | 0.876 |
| CYP20A1 | FBLIM1 | ENSPPYP00000014631 | ENSPPYP00000002131 | Cytochrome P450 family 20 subfamily A member 1. | Filamin-binding LIM protein 1; Serves as an anchoring site for cell-ECM adhesion proteins and filamin-containing actin filaments. Is implicated in cell shape modulation (spreading) and motility. May participate in the regulation of filamin-mediated cross-linking and stabilization of actin filaments. May also regulate the assembly of filamin-containing signaling complexes that control actin assembly. Promotes dissociation of FLNA from ITGB3 and ITGB7. Promotes activation of integrins and regulates integrin-mediated cell-cell adhesion (By similarity). | 0.750 |
| CYP20A1 | FKBP14 | ENSPPYP00000014631 | ENSPPYP00000019820 | Cytochrome P450 family 20 subfamily A member 1. | Peptidyl-prolyl cis-trans isomerase FKBP14; PPIase which accelerates the folding of proteins during protein synthesis. Has a preference for substrates containing 4- hydroxylproline modifications, including type III collagen. May also target type VI and type X collagens. | 0.538 |
| CYP20A1 | RAB3IP | ENSPPYP00000014631 | ENSPPYP00000005426 | Cytochrome P450 family 20 subfamily A member 1. | T0046992 isoform 1. | 0.877 |
