Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
GLCCI1GLCCI1 isoform 2. (394 aa)    
Predicted Functional Partners:
DYRK1A
DYRK1A isoform 7.
   
 
 0.817
DYRK1B
Dual specificity tyrosine phosphorylation regulated kinase 1B.
   
 
 0.655
NUP188
NUP188 isoform 1.
      
 0.636
NUP205
NUP205 isoform 1.
      
 0.568
DYNLL1
Dynein light chain.
    
   0.505
C18orf63
Chromosome 18 open reading frame 63.
      
 0.502
TMCO1
Calcium load-activated calcium channel; Calcium-selective channel required to prevent calcium stores from overfilling, thereby playing a key role in calcium homeostasis. In response to endoplasmic reticulum overloading, assembles into a homotetramer, forming a functional calcium-selective channel, regulating the calcium content in endoplasmic reticulum store.
      
 0.483
CCDC73
CCDC73 isoform 2.
      
 0.474
TSC22D2
TSC22 domain family member 2.
    
 
 0.474
AMER1
APC membrane recruitment protein 1.
      
 0.467
Your Current Organism:
Pongo abelii
NCBI taxonomy Id: 9601
Other names: Orang-utan, Orangutan, P. abelii, Pongo pygmaeus abeli, Pongo pygmaeus abelii, Sumatran orangutan, orang utan
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