STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SEMA3CSemaphorin-3C; Binds to plexin family members and plays an important role in the regulation of developmental processes. Required for normal cardiovascular development during embryogenesis. Functions as attractant for growing axons, and thereby plays an important role in axon growth and axon guidance (By similarity). (754 aa)    
Predicted Functional Partners:
NRP1
Neuropilin; Belongs to the neuropilin family.
  
 
 0.987
PLXND1
PLXND1 isoform 1.
    
 0.869
NRP2
Neuropilin; Belongs to the neuropilin family.
    
 
 0.831
PLXNA1
PLXNA1 isoform 1.
    
 0.822
PLXNA2
PLXNA2 isoform 1.
    
0.812
PLXNA3
PLXNA3 isoform 1.
    
 0.767
PRDM1
PR/SET domain 1.
      
 0.738
PLXNA4
PLXNA4 isoform 2.
    
 0.684
GATA6
GATA6 isoform 1.
      
 0.645
MST1R
MST1R isoform 1.
    
 0.617
Your Current Organism:
Pongo abelii
NCBI taxonomy Id: 9601
Other names: Orang-utan, Orangutan, P. abelii, Pongo pygmaeus abeli, Pongo pygmaeus abelii, Sumatran orangutan, orang utan
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.