HBP1 protein (Pongo abelii) - STRING interaction network

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HBP1

HMG box-containing protein 1; Transcriptional repressor that binds to the promoter region of target genes. Plays a role in the regulation of the cell cycle and of the Wnt pathway. Binds preferentially to the sequence 5'- TTCATTCATTCA-3'. Binding to the histone H1.0 promoter is enhanced by interaction with RB1. Disrupts the interaction between DNA and TCF4 (By similarity). (527 aa)

Predicted Functional Partners:

SIN3A

0.901

RMND5A

0.576

SIN3B

0.540

GID8

0.512

ZBTB7A

0.457

ARMC8

0.431

ARID2

0.425

DDIT4

0.416

ATXN1

0.414

ATXN1L

0.401

Your Current Organism:

Pongo abelii

NCBI taxonomy Id: 9601
Other names: Orang-utan, Orangutan, P. abelii, Pongo pygmaeus abeli, Pongo pygmaeus abelii, Sumatran orangutan, orang utan

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ARID2	HBP1	ENSPPYP00000005060	ENSPPYP00000020062	AT-rich interaction domain 2.	HMG box-containing protein 1; Transcriptional repressor that binds to the promoter region of target genes. Plays a role in the regulation of the cell cycle and of the Wnt pathway. Binds preferentially to the sequence 5'- TTCATTCATTCA-3'. Binding to the histone H1.0 promoter is enhanced by interaction with RB1. Disrupts the interaction between DNA and TCF4 (By similarity).	0.425
ARMC8	GID8	ENSPPYP00000015819	ENSPPYP00000012537	Armadillo repeat-containing protein 8; Component of the CTLH E3 ubiquitin-protein ligase complex that selectively accepts ubiquitin from UBE2H and mediates ubiquitination and subsequent proteasomal degradation of the transcription factor HBP1.	GID8 isoform 1.	0.973
ARMC8	HBP1	ENSPPYP00000015819	ENSPPYP00000020062	Armadillo repeat-containing protein 8; Component of the CTLH E3 ubiquitin-protein ligase complex that selectively accepts ubiquitin from UBE2H and mediates ubiquitination and subsequent proteasomal degradation of the transcription factor HBP1.	HMG box-containing protein 1; Transcriptional repressor that binds to the promoter region of target genes. Plays a role in the regulation of the cell cycle and of the Wnt pathway. Binds preferentially to the sequence 5'- TTCATTCATTCA-3'. Binding to the histone H1.0 promoter is enhanced by interaction with RB1. Disrupts the interaction between DNA and TCF4 (By similarity).	0.431
ARMC8	RMND5A	ENSPPYP00000015819	ENSPPYP00000013613	Armadillo repeat-containing protein 8; Component of the CTLH E3 ubiquitin-protein ligase complex that selectively accepts ubiquitin from UBE2H and mediates ubiquitination and subsequent proteasomal degradation of the transcription factor HBP1.	Required for meiotic nuclear division 5 homolog A.	0.955
ATXN1	ATXN1L	ENSPPYP00000018177	ENSPPYP00000024016	ATXN1 isoform 1.	ATXN1L isoform 2.	0.945
ATXN1	HBP1	ENSPPYP00000018177	ENSPPYP00000020062	ATXN1 isoform 1.	HMG box-containing protein 1; Transcriptional repressor that binds to the promoter region of target genes. Plays a role in the regulation of the cell cycle and of the Wnt pathway. Binds preferentially to the sequence 5'- TTCATTCATTCA-3'. Binding to the histone H1.0 promoter is enhanced by interaction with RB1. Disrupts the interaction between DNA and TCF4 (By similarity).	0.414
ATXN1L	ATXN1	ENSPPYP00000024016	ENSPPYP00000018177	ATXN1L isoform 2.	ATXN1 isoform 1.	0.945
ATXN1L	HBP1	ENSPPYP00000024016	ENSPPYP00000020062	ATXN1L isoform 2.	HMG box-containing protein 1; Transcriptional repressor that binds to the promoter region of target genes. Plays a role in the regulation of the cell cycle and of the Wnt pathway. Binds preferentially to the sequence 5'- TTCATTCATTCA-3'. Binding to the histone H1.0 promoter is enhanced by interaction with RB1. Disrupts the interaction between DNA and TCF4 (By similarity).	0.401
DDIT4	HBP1	ENSPPYP00000002733	ENSPPYP00000020062	DNA damage inducible transcript 4.	HMG box-containing protein 1; Transcriptional repressor that binds to the promoter region of target genes. Plays a role in the regulation of the cell cycle and of the Wnt pathway. Binds preferentially to the sequence 5'- TTCATTCATTCA-3'. Binding to the histone H1.0 promoter is enhanced by interaction with RB1. Disrupts the interaction between DNA and TCF4 (By similarity).	0.416
GID8	ARMC8	ENSPPYP00000012537	ENSPPYP00000015819	GID8 isoform 1.	Armadillo repeat-containing protein 8; Component of the CTLH E3 ubiquitin-protein ligase complex that selectively accepts ubiquitin from UBE2H and mediates ubiquitination and subsequent proteasomal degradation of the transcription factor HBP1.	0.973
GID8	HBP1	ENSPPYP00000012537	ENSPPYP00000020062	GID8 isoform 1.	HMG box-containing protein 1; Transcriptional repressor that binds to the promoter region of target genes. Plays a role in the regulation of the cell cycle and of the Wnt pathway. Binds preferentially to the sequence 5'- TTCATTCATTCA-3'. Binding to the histone H1.0 promoter is enhanced by interaction with RB1. Disrupts the interaction between DNA and TCF4 (By similarity).	0.512
GID8	RMND5A	ENSPPYP00000012537	ENSPPYP00000013613	GID8 isoform 1.	Required for meiotic nuclear division 5 homolog A.	0.974
HBP1	ARID2	ENSPPYP00000020062	ENSPPYP00000005060	HMG box-containing protein 1; Transcriptional repressor that binds to the promoter region of target genes. Plays a role in the regulation of the cell cycle and of the Wnt pathway. Binds preferentially to the sequence 5'- TTCATTCATTCA-3'. Binding to the histone H1.0 promoter is enhanced by interaction with RB1. Disrupts the interaction between DNA and TCF4 (By similarity).	AT-rich interaction domain 2.	0.425
HBP1	ARMC8	ENSPPYP00000020062	ENSPPYP00000015819	HMG box-containing protein 1; Transcriptional repressor that binds to the promoter region of target genes. Plays a role in the regulation of the cell cycle and of the Wnt pathway. Binds preferentially to the sequence 5'- TTCATTCATTCA-3'. Binding to the histone H1.0 promoter is enhanced by interaction with RB1. Disrupts the interaction between DNA and TCF4 (By similarity).	Armadillo repeat-containing protein 8; Component of the CTLH E3 ubiquitin-protein ligase complex that selectively accepts ubiquitin from UBE2H and mediates ubiquitination and subsequent proteasomal degradation of the transcription factor HBP1.	0.431
HBP1	ATXN1	ENSPPYP00000020062	ENSPPYP00000018177	HMG box-containing protein 1; Transcriptional repressor that binds to the promoter region of target genes. Plays a role in the regulation of the cell cycle and of the Wnt pathway. Binds preferentially to the sequence 5'- TTCATTCATTCA-3'. Binding to the histone H1.0 promoter is enhanced by interaction with RB1. Disrupts the interaction between DNA and TCF4 (By similarity).	ATXN1 isoform 1.	0.414
HBP1	ATXN1L	ENSPPYP00000020062	ENSPPYP00000024016	HMG box-containing protein 1; Transcriptional repressor that binds to the promoter region of target genes. Plays a role in the regulation of the cell cycle and of the Wnt pathway. Binds preferentially to the sequence 5'- TTCATTCATTCA-3'. Binding to the histone H1.0 promoter is enhanced by interaction with RB1. Disrupts the interaction between DNA and TCF4 (By similarity).	ATXN1L isoform 2.	0.401
HBP1	DDIT4	ENSPPYP00000020062	ENSPPYP00000002733	HMG box-containing protein 1; Transcriptional repressor that binds to the promoter region of target genes. Plays a role in the regulation of the cell cycle and of the Wnt pathway. Binds preferentially to the sequence 5'- TTCATTCATTCA-3'. Binding to the histone H1.0 promoter is enhanced by interaction with RB1. Disrupts the interaction between DNA and TCF4 (By similarity).	DNA damage inducible transcript 4.	0.416
HBP1	GID8	ENSPPYP00000020062	ENSPPYP00000012537	HMG box-containing protein 1; Transcriptional repressor that binds to the promoter region of target genes. Plays a role in the regulation of the cell cycle and of the Wnt pathway. Binds preferentially to the sequence 5'- TTCATTCATTCA-3'. Binding to the histone H1.0 promoter is enhanced by interaction with RB1. Disrupts the interaction between DNA and TCF4 (By similarity).	GID8 isoform 1.	0.512
HBP1	RMND5A	ENSPPYP00000020062	ENSPPYP00000013613	HMG box-containing protein 1; Transcriptional repressor that binds to the promoter region of target genes. Plays a role in the regulation of the cell cycle and of the Wnt pathway. Binds preferentially to the sequence 5'- TTCATTCATTCA-3'. Binding to the histone H1.0 promoter is enhanced by interaction with RB1. Disrupts the interaction between DNA and TCF4 (By similarity).	Required for meiotic nuclear division 5 homolog A.	0.576
HBP1	SIN3A	ENSPPYP00000020062	ENSPPYP00000007556	HMG box-containing protein 1; Transcriptional repressor that binds to the promoter region of target genes. Plays a role in the regulation of the cell cycle and of the Wnt pathway. Binds preferentially to the sequence 5'- TTCATTCATTCA-3'. Binding to the histone H1.0 promoter is enhanced by interaction with RB1. Disrupts the interaction between DNA and TCF4 (By similarity).	SIN3 transcription regulator family member A.	0.901

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