| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| FBLIM1 | FLNA | ENSPPYP00000002131 | ENSPPYP00000023360 | Filamin-binding LIM protein 1; Serves as an anchoring site for cell-ECM adhesion proteins and filamin-containing actin filaments. Is implicated in cell shape modulation (spreading) and motility. May participate in the regulation of filamin-mediated cross-linking and stabilization of actin filaments. May also regulate the assembly of filamin-containing signaling complexes that control actin assembly. Promotes dissociation of FLNA from ITGB3 and ITGB7. Promotes activation of integrins and regulates integrin-mediated cell-cell adhesion (By similarity). | FLNA isoform 7. | 0.982 |
| FBLIM1 | FLNB | ENSPPYP00000002131 | ENSPPYP00000015399 | Filamin-binding LIM protein 1; Serves as an anchoring site for cell-ECM adhesion proteins and filamin-containing actin filaments. Is implicated in cell shape modulation (spreading) and motility. May participate in the regulation of filamin-mediated cross-linking and stabilization of actin filaments. May also regulate the assembly of filamin-containing signaling complexes that control actin assembly. Promotes dissociation of FLNA from ITGB3 and ITGB7. Promotes activation of integrins and regulates integrin-mediated cell-cell adhesion (By similarity). | FLNB isoform 3. | 0.952 |
| FBLIM1 | FLNC | ENSPPYP00000002131 | ENSPPYP00000020178 | Filamin-binding LIM protein 1; Serves as an anchoring site for cell-ECM adhesion proteins and filamin-containing actin filaments. Is implicated in cell shape modulation (spreading) and motility. May participate in the regulation of filamin-mediated cross-linking and stabilization of actin filaments. May also regulate the assembly of filamin-containing signaling complexes that control actin assembly. Promotes dissociation of FLNA from ITGB3 and ITGB7. Promotes activation of integrins and regulates integrin-mediated cell-cell adhesion (By similarity). | FLNC isoform 2. | 0.976 |
| FLNA | FBLIM1 | ENSPPYP00000023360 | ENSPPYP00000002131 | FLNA isoform 7. | Filamin-binding LIM protein 1; Serves as an anchoring site for cell-ECM adhesion proteins and filamin-containing actin filaments. Is implicated in cell shape modulation (spreading) and motility. May participate in the regulation of filamin-mediated cross-linking and stabilization of actin filaments. May also regulate the assembly of filamin-containing signaling complexes that control actin assembly. Promotes dissociation of FLNA from ITGB3 and ITGB7. Promotes activation of integrins and regulates integrin-mediated cell-cell adhesion (By similarity). | 0.982 |
| FLNA | FLNB | ENSPPYP00000023360 | ENSPPYP00000015399 | FLNA isoform 7. | FLNB isoform 3. | 0.996 |
| FLNA | FLNC | ENSPPYP00000023360 | ENSPPYP00000020178 | FLNA isoform 7. | FLNC isoform 2. | 0.892 |
| FLNA | HSPB7 | ENSPPYP00000023360 | ENSPPYP00000002126 | FLNA isoform 7. | HSPB7 isoform 4; Belongs to the small heat shock protein (HSP20) family. | 0.866 |
| FLNA | ITGB3 | ENSPPYP00000023360 | ENSPPYP00000010043 | FLNA isoform 7. | Integrin beta. | 0.958 |
| FLNA | KCTD13 | ENSPPYP00000023360 | ENSPPYP00000008198 | FLNA isoform 7. | Potassium channel tetramerization domain containing 13. | 0.490 |
| FLNA | MYOZ1 | ENSPPYP00000023360 | ENSPPYP00000002709 | FLNA isoform 7. | MYOZ1 isoform 1. | 0.526 |
| FLNA | OTUD1 | ENSPPYP00000023360 | ENSPPYP00000023490 | FLNA isoform 7. | OTUD1 isoform 1. | 0.699 |
| FLNA | TNFAIP1 | ENSPPYP00000023360 | ENSPPYP00000009095 | FLNA isoform 7. | BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein 2; Substrate-specific adapter of a BCR (BTB-CUL3-RBX1) E3 ubiquitin-protein ligase complex involved in regulation of cytoskeleton structure. The BCR(TNFAIP1) E3 ubiquitin ligase complex mediates the ubiquitination of RHOA, leading to its degradation by the proteasome, thereby regulating the actin cytoskeleton and cell migration. Its interaction with RHOB may regulate apoptosis. May enhance the PCNA- dependent DNA polymerase delta activity (By similarity). | 0.418 |
| FLNB | FBLIM1 | ENSPPYP00000015399 | ENSPPYP00000002131 | FLNB isoform 3. | Filamin-binding LIM protein 1; Serves as an anchoring site for cell-ECM adhesion proteins and filamin-containing actin filaments. Is implicated in cell shape modulation (spreading) and motility. May participate in the regulation of filamin-mediated cross-linking and stabilization of actin filaments. May also regulate the assembly of filamin-containing signaling complexes that control actin assembly. Promotes dissociation of FLNA from ITGB3 and ITGB7. Promotes activation of integrins and regulates integrin-mediated cell-cell adhesion (By similarity). | 0.952 |
| FLNB | FLNA | ENSPPYP00000015399 | ENSPPYP00000023360 | FLNB isoform 3. | FLNA isoform 7. | 0.996 |
| FLNB | FLNC | ENSPPYP00000015399 | ENSPPYP00000020178 | FLNB isoform 3. | FLNC isoform 2. | 0.877 |
| FLNB | HSPB7 | ENSPPYP00000015399 | ENSPPYP00000002126 | FLNB isoform 3. | HSPB7 isoform 4; Belongs to the small heat shock protein (HSP20) family. | 0.520 |
| FLNB | ITGB3 | ENSPPYP00000015399 | ENSPPYP00000010043 | FLNB isoform 3. | Integrin beta. | 0.915 |
| FLNB | KCTD13 | ENSPPYP00000015399 | ENSPPYP00000008198 | FLNB isoform 3. | Potassium channel tetramerization domain containing 13. | 0.490 |
| FLNB | MYOZ1 | ENSPPYP00000015399 | ENSPPYP00000002709 | FLNB isoform 3. | MYOZ1 isoform 1. | 0.526 |
| FLNB | OTUD1 | ENSPPYP00000015399 | ENSPPYP00000023490 | FLNB isoform 3. | OTUD1 isoform 1. | 0.563 |
