| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ARMC8 | MAEA | ENSPPYP00000015819 | ENSPPYP00000016233 | Armadillo repeat-containing protein 8; Component of the CTLH E3 ubiquitin-protein ligase complex that selectively accepts ubiquitin from UBE2H and mediates ubiquitination and subsequent proteasomal degradation of the transcription factor HBP1. | E3 ubiquitin-protein transferase MAEA; Core component of the CTLH E3 ubiquitin-protein ligase complex that selectively accepts ubiquitin from UBE2H and mediates ubiquitination and subsequent proteasomal degradation of the transcription factor HBP1. MAEA and RMND5A are both required for catalytic activity of the CTLH E3 ubiquitin-protein ligase complex. MAEA is required for normal cell proliferation. The CTLH E3 ubiquitin- protein ligase complex is not required for the degradation of enzymes involved in gluconeogenesis, such as FBP1 (By similarity). Plays a role in erythroblast enucleat [...] | 0.994 |
| ARMC8 | RMND5A | ENSPPYP00000015819 | ENSPPYP00000013613 | Armadillo repeat-containing protein 8; Component of the CTLH E3 ubiquitin-protein ligase complex that selectively accepts ubiquitin from UBE2H and mediates ubiquitination and subsequent proteasomal degradation of the transcription factor HBP1. | Required for meiotic nuclear division 5 homolog A. | 0.988 |
| ARMC8 | RMND5B | ENSPPYP00000015819 | ENSPPYP00000018019 | Armadillo repeat-containing protein 8; Component of the CTLH E3 ubiquitin-protein ligase complex that selectively accepts ubiquitin from UBE2H and mediates ubiquitination and subsequent proteasomal degradation of the transcription factor HBP1. | RMND5B isoform 1. | 0.993 |
| ARMC8 | UBE2H | ENSPPYP00000015819 | ENSPPYP00000020192 | Armadillo repeat-containing protein 8; Component of the CTLH E3 ubiquitin-protein ligase complex that selectively accepts ubiquitin from UBE2H and mediates ubiquitination and subsequent proteasomal degradation of the transcription factor HBP1. | Ubiquitin conjugating enzyme E2 H; Belongs to the ubiquitin-conjugating enzyme family. | 0.890 |
| ARMC8 | WDR26 | ENSPPYP00000015819 | ENSPPYP00000000182 | Armadillo repeat-containing protein 8; Component of the CTLH E3 ubiquitin-protein ligase complex that selectively accepts ubiquitin from UBE2H and mediates ubiquitination and subsequent proteasomal degradation of the transcription factor HBP1. | WDR26 isoform 2. | 0.991 |
| MAEA | ARMC8 | ENSPPYP00000016233 | ENSPPYP00000015819 | E3 ubiquitin-protein transferase MAEA; Core component of the CTLH E3 ubiquitin-protein ligase complex that selectively accepts ubiquitin from UBE2H and mediates ubiquitination and subsequent proteasomal degradation of the transcription factor HBP1. MAEA and RMND5A are both required for catalytic activity of the CTLH E3 ubiquitin-protein ligase complex. MAEA is required for normal cell proliferation. The CTLH E3 ubiquitin- protein ligase complex is not required for the degradation of enzymes involved in gluconeogenesis, such as FBP1 (By similarity). Plays a role in erythroblast enucleat [...] | Armadillo repeat-containing protein 8; Component of the CTLH E3 ubiquitin-protein ligase complex that selectively accepts ubiquitin from UBE2H and mediates ubiquitination and subsequent proteasomal degradation of the transcription factor HBP1. | 0.994 |
| MAEA | RMND5A | ENSPPYP00000016233 | ENSPPYP00000013613 | E3 ubiquitin-protein transferase MAEA; Core component of the CTLH E3 ubiquitin-protein ligase complex that selectively accepts ubiquitin from UBE2H and mediates ubiquitination and subsequent proteasomal degradation of the transcription factor HBP1. MAEA and RMND5A are both required for catalytic activity of the CTLH E3 ubiquitin-protein ligase complex. MAEA is required for normal cell proliferation. The CTLH E3 ubiquitin- protein ligase complex is not required for the degradation of enzymes involved in gluconeogenesis, such as FBP1 (By similarity). Plays a role in erythroblast enucleat [...] | Required for meiotic nuclear division 5 homolog A. | 0.997 |
| MAEA | RMND5B | ENSPPYP00000016233 | ENSPPYP00000018019 | E3 ubiquitin-protein transferase MAEA; Core component of the CTLH E3 ubiquitin-protein ligase complex that selectively accepts ubiquitin from UBE2H and mediates ubiquitination and subsequent proteasomal degradation of the transcription factor HBP1. MAEA and RMND5A are both required for catalytic activity of the CTLH E3 ubiquitin-protein ligase complex. MAEA is required for normal cell proliferation. The CTLH E3 ubiquitin- protein ligase complex is not required for the degradation of enzymes involved in gluconeogenesis, such as FBP1 (By similarity). Plays a role in erythroblast enucleat [...] | RMND5B isoform 1. | 0.996 |
| MAEA | UBA52 | ENSPPYP00000016233 | ENSPPYP00000010917 | E3 ubiquitin-protein transferase MAEA; Core component of the CTLH E3 ubiquitin-protein ligase complex that selectively accepts ubiquitin from UBE2H and mediates ubiquitination and subsequent proteasomal degradation of the transcription factor HBP1. MAEA and RMND5A are both required for catalytic activity of the CTLH E3 ubiquitin-protein ligase complex. MAEA is required for normal cell proliferation. The CTLH E3 ubiquitin- protein ligase complex is not required for the degradation of enzymes involved in gluconeogenesis, such as FBP1 (By similarity). Plays a role in erythroblast enucleat [...] | UBA52 isoform 10. | 0.812 |
| MAEA | UBC | ENSPPYP00000016233 | ENSPPYP00000005811 | E3 ubiquitin-protein transferase MAEA; Core component of the CTLH E3 ubiquitin-protein ligase complex that selectively accepts ubiquitin from UBE2H and mediates ubiquitination and subsequent proteasomal degradation of the transcription factor HBP1. MAEA and RMND5A are both required for catalytic activity of the CTLH E3 ubiquitin-protein ligase complex. MAEA is required for normal cell proliferation. The CTLH E3 ubiquitin- protein ligase complex is not required for the degradation of enzymes involved in gluconeogenesis, such as FBP1 (By similarity). Plays a role in erythroblast enucleat [...] | UBC isoform 2. | 0.823 |
| MAEA | UBE2H | ENSPPYP00000016233 | ENSPPYP00000020192 | E3 ubiquitin-protein transferase MAEA; Core component of the CTLH E3 ubiquitin-protein ligase complex that selectively accepts ubiquitin from UBE2H and mediates ubiquitination and subsequent proteasomal degradation of the transcription factor HBP1. MAEA and RMND5A are both required for catalytic activity of the CTLH E3 ubiquitin-protein ligase complex. MAEA is required for normal cell proliferation. The CTLH E3 ubiquitin- protein ligase complex is not required for the degradation of enzymes involved in gluconeogenesis, such as FBP1 (By similarity). Plays a role in erythroblast enucleat [...] | Ubiquitin conjugating enzyme E2 H; Belongs to the ubiquitin-conjugating enzyme family. | 0.869 |
| MAEA | WDR26 | ENSPPYP00000016233 | ENSPPYP00000000182 | E3 ubiquitin-protein transferase MAEA; Core component of the CTLH E3 ubiquitin-protein ligase complex that selectively accepts ubiquitin from UBE2H and mediates ubiquitination and subsequent proteasomal degradation of the transcription factor HBP1. MAEA and RMND5A are both required for catalytic activity of the CTLH E3 ubiquitin-protein ligase complex. MAEA is required for normal cell proliferation. The CTLH E3 ubiquitin- protein ligase complex is not required for the degradation of enzymes involved in gluconeogenesis, such as FBP1 (By similarity). Plays a role in erythroblast enucleat [...] | WDR26 isoform 2. | 0.982 |
| RMND5A | ARMC8 | ENSPPYP00000013613 | ENSPPYP00000015819 | Required for meiotic nuclear division 5 homolog A. | Armadillo repeat-containing protein 8; Component of the CTLH E3 ubiquitin-protein ligase complex that selectively accepts ubiquitin from UBE2H and mediates ubiquitination and subsequent proteasomal degradation of the transcription factor HBP1. | 0.988 |
| RMND5A | MAEA | ENSPPYP00000013613 | ENSPPYP00000016233 | Required for meiotic nuclear division 5 homolog A. | E3 ubiquitin-protein transferase MAEA; Core component of the CTLH E3 ubiquitin-protein ligase complex that selectively accepts ubiquitin from UBE2H and mediates ubiquitination and subsequent proteasomal degradation of the transcription factor HBP1. MAEA and RMND5A are both required for catalytic activity of the CTLH E3 ubiquitin-protein ligase complex. MAEA is required for normal cell proliferation. The CTLH E3 ubiquitin- protein ligase complex is not required for the degradation of enzymes involved in gluconeogenesis, such as FBP1 (By similarity). Plays a role in erythroblast enucleat [...] | 0.997 |
| RMND5A | RMND5B | ENSPPYP00000013613 | ENSPPYP00000018019 | Required for meiotic nuclear division 5 homolog A. | RMND5B isoform 1. | 0.917 |
| RMND5A | UBA52 | ENSPPYP00000013613 | ENSPPYP00000010917 | Required for meiotic nuclear division 5 homolog A. | UBA52 isoform 10. | 0.803 |
| RMND5A | UBC | ENSPPYP00000013613 | ENSPPYP00000005811 | Required for meiotic nuclear division 5 homolog A. | UBC isoform 2. | 0.815 |
| RMND5A | UBE2H | ENSPPYP00000013613 | ENSPPYP00000020192 | Required for meiotic nuclear division 5 homolog A. | Ubiquitin conjugating enzyme E2 H; Belongs to the ubiquitin-conjugating enzyme family. | 0.850 |
| RMND5A | WDR26 | ENSPPYP00000013613 | ENSPPYP00000000182 | Required for meiotic nuclear division 5 homolog A. | WDR26 isoform 2. | 0.992 |
| RMND5B | ARMC8 | ENSPPYP00000018019 | ENSPPYP00000015819 | RMND5B isoform 1. | Armadillo repeat-containing protein 8; Component of the CTLH E3 ubiquitin-protein ligase complex that selectively accepts ubiquitin from UBE2H and mediates ubiquitination and subsequent proteasomal degradation of the transcription factor HBP1. | 0.993 |
