NOS3 protein (Pongo abelii) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Current Organism:

Pongo abelii

NCBI taxonomy Id: 9601
Other names: Orang-utan, Orangutan, P. abelii, Pongo pygmaeus abeli, Pongo pygmaeus abelii, Sumatran orangutan, orang utan

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structured XML interaction data, according to the 'PSI-MI' data standard

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AKT1	AKT2	ENSPPYP00000007036	ENSPPYP00000011178	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	0.999
AKT1	AKT3	ENSPPYP00000007036	ENSPPYP00000000057	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	0.991
AKT1	CALM1	ENSPPYP00000007036	ENSPPYP00000006891	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Calmodulin; Calmodulin mediates the control of a large number of enzymes, ion channels, aquaporins and other proteins by Ca(2+). Among the enzymes to be stimulated by the calmodulin-Ca(2+) complex are a number of protein kinases and phosphatases (By similarity). Together with CCP110 and centrin, is involved in a genetic pathway that regulates the centrosome cycle and progression through cytokinesis (By similarity).	0.417
AKT1	CALML3	ENSPPYP00000007036	ENSPPYP00000002383	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	CALML3 isoform 1; Belongs to the calmodulin family.	0.524
AKT1	CALML4	ENSPPYP00000007036	ENSPPYP00000007472	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	LOW QUALITY PROTEIN: calmodulin-like protein 4.	0.490
AKT1	CALML5	ENSPPYP00000007036	ENSPPYP00000002382	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Calmodulin like 5.	0.531
AKT1	CALML6	ENSPPYP00000007036	ENSPPYP00000002306	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Calmodulin like 6.	0.464
AKT1	NOS3	ENSPPYP00000007036	ENSPPYP00000020384	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	NOS3 isoform 2.	0.998
AKT2	AKT1	ENSPPYP00000011178	ENSPPYP00000007036	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	0.999
AKT2	AKT3	ENSPPYP00000011178	ENSPPYP00000000057	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	0.984
AKT2	NOS3	ENSPPYP00000011178	ENSPPYP00000020384	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	NOS3 isoform 2.	0.972
AKT3	AKT1	ENSPPYP00000000057	ENSPPYP00000007036	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	0.991
AKT3	AKT2	ENSPPYP00000000057	ENSPPYP00000011178	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	0.984
AKT3	NOS3	ENSPPYP00000000057	ENSPPYP00000020384	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	NOS3 isoform 2.	0.972
ARG1	NOS3	ENSPPYP00000019045	ENSPPYP00000020384	Arginase.	NOS3 isoform 2.	0.965
CALM1	AKT1	ENSPPYP00000006891	ENSPPYP00000007036	Calmodulin; Calmodulin mediates the control of a large number of enzymes, ion channels, aquaporins and other proteins by Ca(2+). Among the enzymes to be stimulated by the calmodulin-Ca(2+) complex are a number of protein kinases and phosphatases (By similarity). Together with CCP110 and centrin, is involved in a genetic pathway that regulates the centrosome cycle and progression through cytokinesis (By similarity).	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	0.417
CALM1	CALML3	ENSPPYP00000006891	ENSPPYP00000002383	Calmodulin; Calmodulin mediates the control of a large number of enzymes, ion channels, aquaporins and other proteins by Ca(2+). Among the enzymes to be stimulated by the calmodulin-Ca(2+) complex are a number of protein kinases and phosphatases (By similarity). Together with CCP110 and centrin, is involved in a genetic pathway that regulates the centrosome cycle and progression through cytokinesis (By similarity).	CALML3 isoform 1; Belongs to the calmodulin family.	0.955
CALM1	CALML4	ENSPPYP00000006891	ENSPPYP00000007472	Calmodulin; Calmodulin mediates the control of a large number of enzymes, ion channels, aquaporins and other proteins by Ca(2+). Among the enzymes to be stimulated by the calmodulin-Ca(2+) complex are a number of protein kinases and phosphatases (By similarity). Together with CCP110 and centrin, is involved in a genetic pathway that regulates the centrosome cycle and progression through cytokinesis (By similarity).	LOW QUALITY PROTEIN: calmodulin-like protein 4.	0.948
CALM1	CALML5	ENSPPYP00000006891	ENSPPYP00000002382	Calmodulin; Calmodulin mediates the control of a large number of enzymes, ion channels, aquaporins and other proteins by Ca(2+). Among the enzymes to be stimulated by the calmodulin-Ca(2+) complex are a number of protein kinases and phosphatases (By similarity). Together with CCP110 and centrin, is involved in a genetic pathway that regulates the centrosome cycle and progression through cytokinesis (By similarity).	Calmodulin like 5.	0.923
CALM1	CALML6	ENSPPYP00000006891	ENSPPYP00000002306	Calmodulin; Calmodulin mediates the control of a large number of enzymes, ion channels, aquaporins and other proteins by Ca(2+). Among the enzymes to be stimulated by the calmodulin-Ca(2+) complex are a number of protein kinases and phosphatases (By similarity). Together with CCP110 and centrin, is involved in a genetic pathway that regulates the centrosome cycle and progression through cytokinesis (By similarity).	Calmodulin like 6.	0.947