STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
FASTKFas activated serine/threonine kinase. (549 aa)    
Predicted Functional Partners:
FASTKD2
FAST kinase domain-containing protein 2, mitochondrial; Plays an important role in assembly of the mitochondrial large ribosomal subunit. As a component of a functional protein-RNA module, consisting of RCC1L, NGRN, RPUSD3, RPUSD4, TRUB2, FASTKD2 and 16S mitochondrial ribosomal RNA (16S mt-rRNA), controls 16S mt-rRNA abundance and is required for intra-mitochondrial translation.
      
 0.719
NDUFS2
NADH:ubiquinone oxidoreductase core subunit S2; Belongs to the complex I 49 kDa subunit family.
   
  
 0.589
NPPB
Natriuretic peptide B.
      
 0.557
FASTKD1
FASTKD1 isoform 1.
      
 0.551
ND6
NADH-ubiquinone oxidoreductase chain 6; Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity).
      
 0.497
GRSF1
GRSF1 isoform 2.
    
 
 0.468
SHARPIN
SHARPIN isoform 2.
   
  
 0.460
EIF4E
EIF4E isoform 1; Belongs to the eukaryotic initiation factor 4E family.
      
 0.457
GPR50
G protein-coupled receptor 50; Belongs to the G-protein coupled receptor 1 family.
  
   
 0.426
NPPA
Natriuretic peptide A.
      
 0.422
Your Current Organism:
Pongo abelii
NCBI taxonomy Id: 9601
Other names: Orang-utan, Orangutan, P. abelii, Pongo pygmaeus abeli, Pongo pygmaeus abelii, Sumatran orangutan, orang utan
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.