Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
REEP4Receptor expression-enhancing protein 4; Microtubule-binding protein required to ensure proper cell division and nuclear envelope reassembly by sequestering the endoplasmic reticulum away from chromosomes during mitosis. Probably acts by clearing the endoplasmic reticulum membrane from metaphase chromosomes (By similarity); Belongs to the DP1 family. (257 aa)    
Predicted Functional Partners:
CR201_G0049470
Receptor expression-enhancing protein.
    
 
 0.793
REEP2
Receptor expression-enhancing protein.
    
 
 0.785
RAB3GAP2
RAB3GAP2 isoform 1.
      
 0.727
RETREG3
Reticulophagy regulator family member 3.
    
 
 0.722
ATL3
ATL3 isoform 1.
   
 
 0.716
ATL1
Atlastin-1; GTPase tethering membranes through formation of trans- homooligomers and mediating homotypic fusion of endoplasmic reticulum membranes. Functions in endoplasmic reticulum tubular network biogenesis. May also regulate Golgi biogenesis. May regulate axonal development.
   
 
 0.709
C2CD2
C2CD2 isoform 3.
      
 0.658
NBAS
NBAS isoform 1.
      
 0.639
CAMSAP1
CAMSAP1 isoform 1.
      
 0.634
SEC22A
SEC22 homolog A, vesicle trafficking protein; Belongs to the synaptobrevin family.
      
 0.607
Your Current Organism:
Pongo abelii
NCBI taxonomy Id: 9601
Other names: Orang-utan, Orangutan, P. abelii, Pongo pygmaeus abeli, Pongo pygmaeus abelii, Sumatran orangutan, orang utan
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