Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
PPP3CCSerine/threonine-protein phosphatase. (511 aa)    
Predicted Functional Partners:
PPP3CB
Serine/threonine-protein phosphatase.
  
0.999
PPP3CA
Serine/threonine-protein phosphatase.
  
0.991
NFATC1
NFATC1 isoform 10.
    
 0.981
GSK3B
GSK3B isoform 2; Belongs to the protein kinase superfamily.
    
 0.971
NFATC2
Nuclear factor of activated T cells 2.
    
 0.964
NFATC3
Nuclear factor of activated T cells 3.
    
 0.960
CRTC2
CRTC2 isoform 3.
    
 0.957
CALML5
Calmodulin like 5.
    
 0.957
CALM1
Calmodulin; Calmodulin mediates the control of a large number of enzymes, ion channels, aquaporins and other proteins by Ca(2+). Among the enzymes to be stimulated by the calmodulin-Ca(2+) complex are a number of protein kinases and phosphatases (By similarity). Together with CCP110 and centrin, is involved in a genetic pathway that regulates the centrosome cycle and progression through cytokinesis (By similarity).
    
 0.957
NFATC4
NFATC4 isoform 21.
    
 0.955
Your Current Organism:
Pongo abelii
NCBI taxonomy Id: 9601
Other names: Orang-utan, Orangutan, P. abelii, Pongo pygmaeus abeli, Pongo pygmaeus abelii, Sumatran orangutan, orang utan
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