Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ASH2LASH2L isoform 3. (628 aa)    
Predicted Functional Partners:
RBBP5
RBBP5 isoform 2.
    
 0.999
WDR5B
WD repeat-containing protein 5B; May function as a substrate receptor for CUL4-DDB1 ubiquitin E3 ligase complex; Belongs to the WD repeat WDR5/wds family.
   
 0.999
KMT2A
Histone-lysine N-methyltransferase; Belongs to the class V-like SAM-binding methyltransferase superfamily. Histone-lysine methyltransferase family. TRX/MLL subfamily.
    
 0.997
KMT2D
KMT2D isoform 2.
    
 0.997
MEN1
MEN1 isoform 1.
    
 0.995
DPY30
Dpy-30 histone methyltransferase complex regulatory subunit.
    
 0.995
CR201_G0034515
SETD1A isoform 1.
    
 0.993
KMT2C
Uncharacterized protein.
    
 0.989
KDM6A
UTY isoform 5.
    
 0.989
SETD1B
SETD1B isoform 3.
    
 0.988
Your Current Organism:
Pongo abelii
NCBI taxonomy Id: 9601
Other names: Orang-utan, Orangutan, P. abelii, Pongo pygmaeus abeli, Pongo pygmaeus abelii, Sumatran orangutan, orang utan
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