PCMTD1 protein (Pongo abelii) - STRING interaction network

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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Your Current Organism:

Pongo abelii

NCBI taxonomy Id: 9601
Other names: Orang-utan, Orangutan, P. abelii, Pongo pygmaeus abeli, Pongo pygmaeus abelii, Sumatran orangutan, orang utan

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ASB11	ASB7	ENSPPYP00000022531	ENSPPYP00000007739	Ankyrin repeat and SOCS box protein 11; May be a substrate-recognition component of a SCF-like ECS (Elongin-Cullin-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins.	Ankyrin repeat and SOCS box protein 7; Probable substrate-recognition component of a SCF-like ECS (Elongin-Cullin-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins; Belongs to the ankyrin SOCS box (ASB) family.	0.933
ASB11	CUL5	ENSPPYP00000022531	ENSPPYP00000004398	Ankyrin repeat and SOCS box protein 11; May be a substrate-recognition component of a SCF-like ECS (Elongin-Cullin-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins.	Cullin-5; Core component of multiple SCF-like ECS (Elongin BC-Cullin 2/5-SOCS-box protein) E3 ubiquitin-protein ligase complexes, which mediate the ubiquitination and subsequent proteasomal degradation of target proteins. As a scaffold protein may contribute to catalysis through positioning of the substrate and the ubiquitin-conjugating enzyme. The functional specificity of the E3 ubiquitin-protein ligase complex depends on the variable substrate recognition component. ECS(SOCS1) seems to direct ubiquitination of JAK2. Seems to be involved in proteosomal degradation of p53/TP53 stimula [...]	0.984
ASB11	PCMTD1	ENSPPYP00000022531	ENSPPYP00000020838	Ankyrin repeat and SOCS box protein 11; May be a substrate-recognition component of a SCF-like ECS (Elongin-Cullin-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins.	Protein-L-isoaspartate O-methyltransferase domain-containing protein 1.	0.900
ASB7	ASB11	ENSPPYP00000007739	ENSPPYP00000022531	Ankyrin repeat and SOCS box protein 7; Probable substrate-recognition component of a SCF-like ECS (Elongin-Cullin-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins; Belongs to the ankyrin SOCS box (ASB) family.	Ankyrin repeat and SOCS box protein 11; May be a substrate-recognition component of a SCF-like ECS (Elongin-Cullin-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins.	0.933
ASB7	CUL5	ENSPPYP00000007739	ENSPPYP00000004398	Ankyrin repeat and SOCS box protein 7; Probable substrate-recognition component of a SCF-like ECS (Elongin-Cullin-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins; Belongs to the ankyrin SOCS box (ASB) family.	Cullin-5; Core component of multiple SCF-like ECS (Elongin BC-Cullin 2/5-SOCS-box protein) E3 ubiquitin-protein ligase complexes, which mediate the ubiquitination and subsequent proteasomal degradation of target proteins. As a scaffold protein may contribute to catalysis through positioning of the substrate and the ubiquitin-conjugating enzyme. The functional specificity of the E3 ubiquitin-protein ligase complex depends on the variable substrate recognition component. ECS(SOCS1) seems to direct ubiquitination of JAK2. Seems to be involved in proteosomal degradation of p53/TP53 stimula [...]	0.990
ASB7	PCMTD1	ENSPPYP00000007739	ENSPPYP00000020838	Ankyrin repeat and SOCS box protein 7; Probable substrate-recognition component of a SCF-like ECS (Elongin-Cullin-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins; Belongs to the ankyrin SOCS box (ASB) family.	Protein-L-isoaspartate O-methyltransferase domain-containing protein 1.	0.910
CUL5	ASB11	ENSPPYP00000004398	ENSPPYP00000022531	Cullin-5; Core component of multiple SCF-like ECS (Elongin BC-Cullin 2/5-SOCS-box protein) E3 ubiquitin-protein ligase complexes, which mediate the ubiquitination and subsequent proteasomal degradation of target proteins. As a scaffold protein may contribute to catalysis through positioning of the substrate and the ubiquitin-conjugating enzyme. The functional specificity of the E3 ubiquitin-protein ligase complex depends on the variable substrate recognition component. ECS(SOCS1) seems to direct ubiquitination of JAK2. Seems to be involved in proteosomal degradation of p53/TP53 stimula [...]	Ankyrin repeat and SOCS box protein 11; May be a substrate-recognition component of a SCF-like ECS (Elongin-Cullin-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins.	0.984
CUL5	ASB7	ENSPPYP00000004398	ENSPPYP00000007739	Cullin-5; Core component of multiple SCF-like ECS (Elongin BC-Cullin 2/5-SOCS-box protein) E3 ubiquitin-protein ligase complexes, which mediate the ubiquitination and subsequent proteasomal degradation of target proteins. As a scaffold protein may contribute to catalysis through positioning of the substrate and the ubiquitin-conjugating enzyme. The functional specificity of the E3 ubiquitin-protein ligase complex depends on the variable substrate recognition component. ECS(SOCS1) seems to direct ubiquitination of JAK2. Seems to be involved in proteosomal degradation of p53/TP53 stimula [...]	Ankyrin repeat and SOCS box protein 7; Probable substrate-recognition component of a SCF-like ECS (Elongin-Cullin-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins; Belongs to the ankyrin SOCS box (ASB) family.	0.990
CUL5	PCMTD1	ENSPPYP00000004398	ENSPPYP00000020838	Cullin-5; Core component of multiple SCF-like ECS (Elongin BC-Cullin 2/5-SOCS-box protein) E3 ubiquitin-protein ligase complexes, which mediate the ubiquitination and subsequent proteasomal degradation of target proteins. As a scaffold protein may contribute to catalysis through positioning of the substrate and the ubiquitin-conjugating enzyme. The functional specificity of the E3 ubiquitin-protein ligase complex depends on the variable substrate recognition component. ECS(SOCS1) seems to direct ubiquitination of JAK2. Seems to be involved in proteosomal degradation of p53/TP53 stimula [...]	Protein-L-isoaspartate O-methyltransferase domain-containing protein 1.	0.976
PCMTD1	ASB11	ENSPPYP00000020838	ENSPPYP00000022531	Protein-L-isoaspartate O-methyltransferase domain-containing protein 1.	Ankyrin repeat and SOCS box protein 11; May be a substrate-recognition component of a SCF-like ECS (Elongin-Cullin-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins.	0.900
PCMTD1	ASB7	ENSPPYP00000020838	ENSPPYP00000007739	Protein-L-isoaspartate O-methyltransferase domain-containing protein 1.	Ankyrin repeat and SOCS box protein 7; Probable substrate-recognition component of a SCF-like ECS (Elongin-Cullin-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins; Belongs to the ankyrin SOCS box (ASB) family.	0.910
PCMTD1	CUL5	ENSPPYP00000020838	ENSPPYP00000004398	Protein-L-isoaspartate O-methyltransferase domain-containing protein 1.	Cullin-5; Core component of multiple SCF-like ECS (Elongin BC-Cullin 2/5-SOCS-box protein) E3 ubiquitin-protein ligase complexes, which mediate the ubiquitination and subsequent proteasomal degradation of target proteins. As a scaffold protein may contribute to catalysis through positioning of the substrate and the ubiquitin-conjugating enzyme. The functional specificity of the E3 ubiquitin-protein ligase complex depends on the variable substrate recognition component. ECS(SOCS1) seems to direct ubiquitination of JAK2. Seems to be involved in proteosomal degradation of p53/TP53 stimula [...]	0.976
PCMTD1	PUS7	ENSPPYP00000020838	ENSPPYP00000020055	Protein-L-isoaspartate O-methyltransferase domain-containing protein 1.	PUS7 isoform 2.	0.549
PCMTD1	SCAF11	ENSPPYP00000020838	ENSPPYP00000005061	Protein-L-isoaspartate O-methyltransferase domain-containing protein 1.	SCAF11 isoform 1.	0.610
PCMTD1	SLC25A32	ENSPPYP00000020838	ENSPPYP00000021098	Protein-L-isoaspartate O-methyltransferase domain-containing protein 1.	SLC25A32 isoform 3; Belongs to the mitochondrial carrier (TC 2.A.29) family.	0.621
PCMTD1	STK31	ENSPPYP00000020838	ENSPPYP00000019867	Protein-L-isoaspartate O-methyltransferase domain-containing protein 1.	Serine/threonine kinase 31.	0.672
PCMTD1	TCAF1	ENSPPYP00000020838	ENSPPYP00000020335	Protein-L-isoaspartate O-methyltransferase domain-containing protein 1.	TRPM8 channel-associated factor 1; Positively regulates the plasma membrane cation channel TRPM8 activity. Involved in the recruitment of TRPM8 to the cell surface. Promotes prostate cancer cell migration inhibition in a TRPM8-dependent manner; Belongs to the TCAF family.	0.591
PCMTD1	TMEM254	ENSPPYP00000020838	ENSPPYP00000002668	Protein-L-isoaspartate O-methyltransferase domain-containing protein 1.	Transmembrane protein 254.	0.561
PCMTD1	WDYHV1	ENSPPYP00000020838	ENSPPYP00000022357	Protein-L-isoaspartate O-methyltransferase domain-containing protein 1.	WDYHV1 isoform 4.	0.823
PUS7	PCMTD1	ENSPPYP00000020055	ENSPPYP00000020838	PUS7 isoform 2.	Protein-L-isoaspartate O-methyltransferase domain-containing protein 1.	0.549