STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CYP7A1Cholesterol 7-alpha-monooxygenase; Belongs to the cytochrome P450 family. (504 aa)    
Predicted Functional Partners:
CR201_G0032337-2
CYP27A1 isoform 5.
  
 
 0.983
CH25H
Cholesterol 25-hydroxylase; Belongs to the sterol desaturase family.
   
 0.974
HSD3B7
Hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 7; Belongs to the 3-beta-HSD family.
   
 0.966
CYP1A1
CYP1A1 isoform 1; Belongs to the cytochrome P450 family.
  
 
 0.957
CYP17A1
CYP17A1 isoform 1; Belongs to the cytochrome P450 family.
  
 
 0.956
HSD3B1
HSD3B1 isoform 1; Belongs to the 3-beta-HSD family.
   
 0.946
CYP3A4
Cytochrome P450 family 3 subfamily A member 4.
  
 
0.934
CYP2E1
CYP2E1 isoform 1; Belongs to the cytochrome P450 family.
  
 
0.931
CYP3A5
CYP3A43 isoform 5; Belongs to the cytochrome P450 family.
  
 
0.928
CR201_G0048502
CYP3A7 isoform 2.
  
 
0.926
Your Current Organism:
Pongo abelii
NCBI taxonomy Id: 9601
Other names: Orang-utan, Orangutan, P. abelii, Pongo pygmaeus abeli, Pongo pygmaeus abelii, Sumatran orangutan, orang utan
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.