| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| CH25H | CR201_G0032337-2 | ENSPPYP00000002851 | ENSPPYP00000014972 | Cholesterol 25-hydroxylase; Belongs to the sterol desaturase family. | CYP27A1 isoform 5. | 0.936 |
| CH25H | CYP46A1 | ENSPPYP00000002851 | ENSPPYP00000006975 | Cholesterol 25-hydroxylase; Belongs to the sterol desaturase family. | CYP46A1 isoform 2; Belongs to the cytochrome P450 family. | 0.952 |
| CH25H | CYP7A1 | ENSPPYP00000002851 | ENSPPYP00000020869 | Cholesterol 25-hydroxylase; Belongs to the sterol desaturase family. | Cholesterol 7-alpha-monooxygenase; Belongs to the cytochrome P450 family. | 0.968 |
| CH25H | HSD3B1 | ENSPPYP00000002851 | ENSPPYP00000001124 | Cholesterol 25-hydroxylase; Belongs to the sterol desaturase family. | HSD3B1 isoform 1; Belongs to the 3-beta-HSD family. | 0.662 |
| CH25H | HSD3B7 | ENSPPYP00000002851 | ENSPPYP00000008246 | Cholesterol 25-hydroxylase; Belongs to the sterol desaturase family. | Hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 7; Belongs to the 3-beta-HSD family. | 0.787 |
| CR201_G0032337-2 | CH25H | ENSPPYP00000014972 | ENSPPYP00000002851 | CYP27A1 isoform 5. | Cholesterol 25-hydroxylase; Belongs to the sterol desaturase family. | 0.936 |
| CR201_G0032337-2 | CYP17A1 | ENSPPYP00000014972 | ENSPPYP00000003038 | CYP27A1 isoform 5. | CYP17A1 isoform 1; Belongs to the cytochrome P450 family. | 0.416 |
| CR201_G0032337-2 | CYP3A4 | ENSPPYP00000014972 | ENSPPYP00000019486 | CYP27A1 isoform 5. | Cytochrome P450 family 3 subfamily A member 4. | 0.405 |
| CR201_G0032337-2 | CYP46A1 | ENSPPYP00000014972 | ENSPPYP00000006975 | CYP27A1 isoform 5. | CYP46A1 isoform 2; Belongs to the cytochrome P450 family. | 0.927 |
| CR201_G0032337-2 | CYP7A1 | ENSPPYP00000014972 | ENSPPYP00000020869 | CYP27A1 isoform 5. | Cholesterol 7-alpha-monooxygenase; Belongs to the cytochrome P450 family. | 0.984 |
| CR201_G0032337-2 | HSD3B7 | ENSPPYP00000014972 | ENSPPYP00000008246 | CYP27A1 isoform 5. | Hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 7; Belongs to the 3-beta-HSD family. | 0.576 |
| CYP17A1 | CR201_G0032337-2 | ENSPPYP00000003038 | ENSPPYP00000014972 | CYP17A1 isoform 1; Belongs to the cytochrome P450 family. | CYP27A1 isoform 5. | 0.416 |
| CYP17A1 | CYP1A1 | ENSPPYP00000003038 | ENSPPYP00000007536 | CYP17A1 isoform 1; Belongs to the cytochrome P450 family. | CYP1A1 isoform 1; Belongs to the cytochrome P450 family. | 0.915 |
| CYP17A1 | CYP1A2 | ENSPPYP00000003038 | ENSPPYP00000007537 | CYP17A1 isoform 1; Belongs to the cytochrome P450 family. | Cytochrome P450 1A2; A cytochrome P450 monooxygenase involved in the metabolism of various endogenous substrates, including fatty acids, steroid hormones and vitamins. Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate, and reducing the second into a water molecule, with two electrons provided by NADPH via cytochrome P450 reductase (NADPH--hemoprotein reductase). Catalyzes the hydroxylation of carbon-hydrogen bonds. Exhibits high catalytic activity for the formation of hydroxyestrogens from estrone (E1) and 17beta-estradiol (E2), namely 2-hydroxy E1 and E [...] | 0.920 |
| CYP17A1 | CYP2E1 | ENSPPYP00000003038 | ENSPPYP00000003264 | CYP17A1 isoform 1; Belongs to the cytochrome P450 family. | CYP2E1 isoform 1; Belongs to the cytochrome P450 family. | 0.919 |
| CYP17A1 | CYP3A4 | ENSPPYP00000003038 | ENSPPYP00000019486 | CYP17A1 isoform 1; Belongs to the cytochrome P450 family. | Cytochrome P450 family 3 subfamily A member 4. | 0.938 |
| CYP17A1 | CYP7A1 | ENSPPYP00000003038 | ENSPPYP00000020869 | CYP17A1 isoform 1; Belongs to the cytochrome P450 family. | Cholesterol 7-alpha-monooxygenase; Belongs to the cytochrome P450 family. | 0.951 |
| CYP17A1 | HSD3B1 | ENSPPYP00000003038 | ENSPPYP00000001124 | CYP17A1 isoform 1; Belongs to the cytochrome P450 family. | HSD3B1 isoform 1; Belongs to the 3-beta-HSD family. | 0.979 |
| CYP17A1 | HSD3B7 | ENSPPYP00000003038 | ENSPPYP00000008246 | CYP17A1 isoform 1; Belongs to the cytochrome P450 family. | Hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 7; Belongs to the 3-beta-HSD family. | 0.431 |
| CYP1A1 | CYP17A1 | ENSPPYP00000007536 | ENSPPYP00000003038 | CYP1A1 isoform 1; Belongs to the cytochrome P450 family. | CYP17A1 isoform 1; Belongs to the cytochrome P450 family. | 0.915 |
