| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ADH1A | ADH7 | ENSPPYP00000016692 | ENSPPYP00000016693 | Alcohol dehydrogenase 1A. | ADH7 isoform 2. | 0.426 |
| ADH1A | ADHFE1 | ENSPPYP00000016692 | ENSPPYP00000020906 | Alcohol dehydrogenase 1A. | Hydroxyacid-oxoacid transhydrogenase, mitochondrial; Catalyzes the cofactor-independent reversible oxidation of gamma-hydroxybutyrate (GHB) to succinic semialdehyde (SSA) coupled to reduction of 2-ketoglutarate (2-KG) to D-2-hydroxyglutarate (D-2-HG). L-3-hydroxybutyrate (L-3-OHB) is also a substrate for HOT when using 2- KG as hydrogen acceptor, resulting in the formation of D-2-HG (By similarity). | 0.886 |
| ADH1A | MRTFA | ENSPPYP00000016692 | ENSPPYP00000013225 | Alcohol dehydrogenase 1A. | MKL1 isoform 5. | 0.443 |
| ADH5 | ADHFE1 | ENSPPYP00000016688 | ENSPPYP00000020906 | S-(hydroxymethyl)glutathione dehydrogenase; Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily. | Hydroxyacid-oxoacid transhydrogenase, mitochondrial; Catalyzes the cofactor-independent reversible oxidation of gamma-hydroxybutyrate (GHB) to succinic semialdehyde (SSA) coupled to reduction of 2-ketoglutarate (2-KG) to D-2-hydroxyglutarate (D-2-HG). L-3-hydroxybutyrate (L-3-OHB) is also a substrate for HOT when using 2- KG as hydrogen acceptor, resulting in the formation of D-2-HG (By similarity). | 0.750 |
| ADH5 | MRTFA | ENSPPYP00000016688 | ENSPPYP00000013225 | S-(hydroxymethyl)glutathione dehydrogenase; Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily. | MKL1 isoform 5. | 0.443 |
| ADH6 | ADH7 | ENSPPYP00000016690 | ENSPPYP00000016693 | Alcohol dehydrogenase 6; Belongs to the zinc-containing alcohol dehydrogenase family. Class-V subfamily. | ADH7 isoform 2. | 0.411 |
| ADH6 | ADHFE1 | ENSPPYP00000016690 | ENSPPYP00000020906 | Alcohol dehydrogenase 6; Belongs to the zinc-containing alcohol dehydrogenase family. Class-V subfamily. | Hydroxyacid-oxoacid transhydrogenase, mitochondrial; Catalyzes the cofactor-independent reversible oxidation of gamma-hydroxybutyrate (GHB) to succinic semialdehyde (SSA) coupled to reduction of 2-ketoglutarate (2-KG) to D-2-hydroxyglutarate (D-2-HG). L-3-hydroxybutyrate (L-3-OHB) is also a substrate for HOT when using 2- KG as hydrogen acceptor, resulting in the formation of D-2-HG (By similarity). | 0.826 |
| ADH6 | MRTFA | ENSPPYP00000016690 | ENSPPYP00000013225 | Alcohol dehydrogenase 6; Belongs to the zinc-containing alcohol dehydrogenase family. Class-V subfamily. | MKL1 isoform 5. | 0.443 |
| ADH7 | ADH1A | ENSPPYP00000016693 | ENSPPYP00000016692 | ADH7 isoform 2. | Alcohol dehydrogenase 1A. | 0.426 |
| ADH7 | ADH6 | ENSPPYP00000016693 | ENSPPYP00000016690 | ADH7 isoform 2. | Alcohol dehydrogenase 6; Belongs to the zinc-containing alcohol dehydrogenase family. Class-V subfamily. | 0.411 |
| ADH7 | ADHFE1 | ENSPPYP00000016693 | ENSPPYP00000020906 | ADH7 isoform 2. | Hydroxyacid-oxoacid transhydrogenase, mitochondrial; Catalyzes the cofactor-independent reversible oxidation of gamma-hydroxybutyrate (GHB) to succinic semialdehyde (SSA) coupled to reduction of 2-ketoglutarate (2-KG) to D-2-hydroxyglutarate (D-2-HG). L-3-hydroxybutyrate (L-3-OHB) is also a substrate for HOT when using 2- KG as hydrogen acceptor, resulting in the formation of D-2-HG (By similarity). | 0.750 |
| ADH7 | MRTFA | ENSPPYP00000016693 | ENSPPYP00000013225 | ADH7 isoform 2. | MKL1 isoform 5. | 0.443 |
| ADHFE1 | ADH1A | ENSPPYP00000020906 | ENSPPYP00000016692 | Hydroxyacid-oxoacid transhydrogenase, mitochondrial; Catalyzes the cofactor-independent reversible oxidation of gamma-hydroxybutyrate (GHB) to succinic semialdehyde (SSA) coupled to reduction of 2-ketoglutarate (2-KG) to D-2-hydroxyglutarate (D-2-HG). L-3-hydroxybutyrate (L-3-OHB) is also a substrate for HOT when using 2- KG as hydrogen acceptor, resulting in the formation of D-2-HG (By similarity). | Alcohol dehydrogenase 1A. | 0.886 |
| ADHFE1 | ADH5 | ENSPPYP00000020906 | ENSPPYP00000016688 | Hydroxyacid-oxoacid transhydrogenase, mitochondrial; Catalyzes the cofactor-independent reversible oxidation of gamma-hydroxybutyrate (GHB) to succinic semialdehyde (SSA) coupled to reduction of 2-ketoglutarate (2-KG) to D-2-hydroxyglutarate (D-2-HG). L-3-hydroxybutyrate (L-3-OHB) is also a substrate for HOT when using 2- KG as hydrogen acceptor, resulting in the formation of D-2-HG (By similarity). | S-(hydroxymethyl)glutathione dehydrogenase; Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily. | 0.750 |
| ADHFE1 | ADH6 | ENSPPYP00000020906 | ENSPPYP00000016690 | Hydroxyacid-oxoacid transhydrogenase, mitochondrial; Catalyzes the cofactor-independent reversible oxidation of gamma-hydroxybutyrate (GHB) to succinic semialdehyde (SSA) coupled to reduction of 2-ketoglutarate (2-KG) to D-2-hydroxyglutarate (D-2-HG). L-3-hydroxybutyrate (L-3-OHB) is also a substrate for HOT when using 2- KG as hydrogen acceptor, resulting in the formation of D-2-HG (By similarity). | Alcohol dehydrogenase 6; Belongs to the zinc-containing alcohol dehydrogenase family. Class-V subfamily. | 0.826 |
| ADHFE1 | ADH7 | ENSPPYP00000020906 | ENSPPYP00000016693 | Hydroxyacid-oxoacid transhydrogenase, mitochondrial; Catalyzes the cofactor-independent reversible oxidation of gamma-hydroxybutyrate (GHB) to succinic semialdehyde (SSA) coupled to reduction of 2-ketoglutarate (2-KG) to D-2-hydroxyglutarate (D-2-HG). L-3-hydroxybutyrate (L-3-OHB) is also a substrate for HOT when using 2- KG as hydrogen acceptor, resulting in the formation of D-2-HG (By similarity). | ADH7 isoform 2. | 0.750 |
| ADHFE1 | AGXT | ENSPPYP00000020906 | ENSPPYP00000014927 | Hydroxyacid-oxoacid transhydrogenase, mitochondrial; Catalyzes the cofactor-independent reversible oxidation of gamma-hydroxybutyrate (GHB) to succinic semialdehyde (SSA) coupled to reduction of 2-ketoglutarate (2-KG) to D-2-hydroxyglutarate (D-2-HG). L-3-hydroxybutyrate (L-3-OHB) is also a substrate for HOT when using 2- KG as hydrogen acceptor, resulting in the formation of D-2-HG (By similarity). | Serine--pyruvate aminotransferase. | 0.783 |
| ADHFE1 | CMBL | ENSPPYP00000020906 | ENSPPYP00000017140 | Hydroxyacid-oxoacid transhydrogenase, mitochondrial; Catalyzes the cofactor-independent reversible oxidation of gamma-hydroxybutyrate (GHB) to succinic semialdehyde (SSA) coupled to reduction of 2-ketoglutarate (2-KG) to D-2-hydroxyglutarate (D-2-HG). L-3-hydroxybutyrate (L-3-OHB) is also a substrate for HOT when using 2- KG as hydrogen acceptor, resulting in the formation of D-2-HG (By similarity). | Carboxymethylenebutenolidase homolog; Cysteine hydrolase; Belongs to the dienelactone hydrolase family. | 0.811 |
| ADHFE1 | ENSPPYP00000018745 | ENSPPYP00000020906 | ENSPPYP00000018745 | Hydroxyacid-oxoacid transhydrogenase, mitochondrial; Catalyzes the cofactor-independent reversible oxidation of gamma-hydroxybutyrate (GHB) to succinic semialdehyde (SSA) coupled to reduction of 2-ketoglutarate (2-KG) to D-2-hydroxyglutarate (D-2-HG). L-3-hydroxybutyrate (L-3-OHB) is also a substrate for HOT when using 2- KG as hydrogen acceptor, resulting in the formation of D-2-HG (By similarity). | annotation not available | 0.750 |
| ADHFE1 | HSDL2 | ENSPPYP00000020906 | ENSPPYP00000021856 | Hydroxyacid-oxoacid transhydrogenase, mitochondrial; Catalyzes the cofactor-independent reversible oxidation of gamma-hydroxybutyrate (GHB) to succinic semialdehyde (SSA) coupled to reduction of 2-ketoglutarate (2-KG) to D-2-hydroxyglutarate (D-2-HG). L-3-hydroxybutyrate (L-3-OHB) is also a substrate for HOT when using 2- KG as hydrogen acceptor, resulting in the formation of D-2-HG (By similarity). | Hydroxysteroid dehydrogenase-like protein 2; Has apparently no steroid dehydrogenase activity. Belongs to the short-chain dehydrogenases/reductases (SDR) family. | 0.876 |
