GDAP1 protein (Pongo abelii) - STRING interaction network

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Predicted Interactions

gene neighborhood

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textmining

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protein homology

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Score

GDAP1

GDAP1 isoform 2; Belongs to the GST superfamily. (358 aa)

Predicted Functional Partners:

UNC5C

0.925

PLTP

0.918

TKTL1

0.778

FIS1

0.734

PEX19

0.694

MFN1

0.688

RNMT

0.681

PEX16

0.674

MPZL1

0.671

CLDN15

0.667

Your Current Organism:

Pongo abelii

NCBI taxonomy Id: 9601
Other names: Orang-utan, Orangutan, P. abelii, Pongo pygmaeus abeli, Pongo pygmaeus abelii, Sumatran orangutan, orang utan

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CLDN15	FIS1	ENSPPYP00000019556	ENSPPYP00000019557	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family.	Mitochondrial fission 1 protein; Involved in the fragmentation of the mitochondrial network and its perinuclear clustering.	0.427
CLDN15	GDAP1	ENSPPYP00000019556	ENSPPYP00000020956	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family.	GDAP1 isoform 2; Belongs to the GST superfamily.	0.667
CLDN15	MFN1	ENSPPYP00000019556	ENSPPYP00000016014	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family.	MFN1 isoform 1; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.	0.433
CLDN15	PEX16	ENSPPYP00000019556	ENSPPYP00000003820	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family.	Peroxisomal membrane protein PEX16.	0.634
CLDN15	PEX19	ENSPPYP00000019556	ENSPPYP00000000743	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family.	Peroxisomal biogenesis factor 19; Necessary for early peroxisomal biogenesis. Acts both as a cytosolic chaperone and as an import receptor for peroxisomal membrane proteins (PMPs). Binds and stabilizes newly synthesized PMPs in the cytoplasm by interacting with their hydrophobic membrane-spanning domains, and targets them to the peroxisome membrane by binding to the integral membrane protein PEX3. Excludes CDKN2A from the nucleus and prevents its interaction with MDM2, which results in active degradation of TP53.	0.722
FIS1	CLDN15	ENSPPYP00000019557	ENSPPYP00000019556	Mitochondrial fission 1 protein; Involved in the fragmentation of the mitochondrial network and its perinuclear clustering.	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family.	0.427
FIS1	GDAP1	ENSPPYP00000019557	ENSPPYP00000020956	Mitochondrial fission 1 protein; Involved in the fragmentation of the mitochondrial network and its perinuclear clustering.	GDAP1 isoform 2; Belongs to the GST superfamily.	0.734
FIS1	MFN1	ENSPPYP00000019557	ENSPPYP00000016014	Mitochondrial fission 1 protein; Involved in the fragmentation of the mitochondrial network and its perinuclear clustering.	MFN1 isoform 1; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.	0.726
FIS1	PEX16	ENSPPYP00000019557	ENSPPYP00000003820	Mitochondrial fission 1 protein; Involved in the fragmentation of the mitochondrial network and its perinuclear clustering.	Peroxisomal membrane protein PEX16.	0.634
FIS1	PEX19	ENSPPYP00000019557	ENSPPYP00000000743	Mitochondrial fission 1 protein; Involved in the fragmentation of the mitochondrial network and its perinuclear clustering.	Peroxisomal biogenesis factor 19; Necessary for early peroxisomal biogenesis. Acts both as a cytosolic chaperone and as an import receptor for peroxisomal membrane proteins (PMPs). Binds and stabilizes newly synthesized PMPs in the cytoplasm by interacting with their hydrophobic membrane-spanning domains, and targets them to the peroxisome membrane by binding to the integral membrane protein PEX3. Excludes CDKN2A from the nucleus and prevents its interaction with MDM2, which results in active degradation of TP53.	0.729
GDAP1	CLDN15	ENSPPYP00000020956	ENSPPYP00000019556	GDAP1 isoform 2; Belongs to the GST superfamily.	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family.	0.667
GDAP1	FIS1	ENSPPYP00000020956	ENSPPYP00000019557	GDAP1 isoform 2; Belongs to the GST superfamily.	Mitochondrial fission 1 protein; Involved in the fragmentation of the mitochondrial network and its perinuclear clustering.	0.734
GDAP1	MFN1	ENSPPYP00000020956	ENSPPYP00000016014	GDAP1 isoform 2; Belongs to the GST superfamily.	MFN1 isoform 1; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.	0.688
GDAP1	MPZL1	ENSPPYP00000020956	ENSPPYP00000000641	GDAP1 isoform 2; Belongs to the GST superfamily.	Myelin protein zero like 1.	0.671
GDAP1	PEX16	ENSPPYP00000020956	ENSPPYP00000003820	GDAP1 isoform 2; Belongs to the GST superfamily.	Peroxisomal membrane protein PEX16.	0.674
GDAP1	PEX19	ENSPPYP00000020956	ENSPPYP00000000743	GDAP1 isoform 2; Belongs to the GST superfamily.	Peroxisomal biogenesis factor 19; Necessary for early peroxisomal biogenesis. Acts both as a cytosolic chaperone and as an import receptor for peroxisomal membrane proteins (PMPs). Binds and stabilizes newly synthesized PMPs in the cytoplasm by interacting with their hydrophobic membrane-spanning domains, and targets them to the peroxisome membrane by binding to the integral membrane protein PEX3. Excludes CDKN2A from the nucleus and prevents its interaction with MDM2, which results in active degradation of TP53.	0.694
GDAP1	PLTP	ENSPPYP00000020956	ENSPPYP00000012381	GDAP1 isoform 2; Belongs to the GST superfamily.	PLTP isoform 3.	0.918
GDAP1	RNMT	ENSPPYP00000020956	ENSPPYP00000010074	GDAP1 isoform 2; Belongs to the GST superfamily.	mRNA cap guanine-N7 methyltransferase.	0.681
GDAP1	TKTL1	ENSPPYP00000020956	ENSPPYP00000023359	GDAP1 isoform 2; Belongs to the GST superfamily.	TKTL1 isoform 1.	0.778
GDAP1	UNC5C	ENSPPYP00000020956	ENSPPYP00000016681	GDAP1 isoform 2; Belongs to the GST superfamily.	UNC5C isoform 1.	0.925