| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| AADAT | CR201_G0050254 | ENSPPYP00000016979 | ENSPPYP00000020986 | Aminoadipate aminotransferase. | RALYL isoform 7. | 0.714 |
| AADAT | RALY | ENSPPYP00000016979 | ENSPPYP00000024392 | Aminoadipate aminotransferase. | RALY heterogeneous nuclear ribonucleoprotein. | 0.568 |
| CELF1 | CR201_G0050254 | ENSPPYP00000003787 | ENSPPYP00000020986 | CUGBP Elav-like family member 1; RNA-binding protein implicated in the regulation of several post-transcriptional events. Involved in pre-mRNA alternative splicing, mRNA translation and stability. Mediates exon inclusion and/or exclusion in pre-mRNA that are subject to tissue-specific and developmentally regulated alternative splicing. Specifically activates exon 5 inclusion of cardiac isoforms of TNNT2 during heart remodeling at the juvenile to adult transition. Acts as both an activator and repressor of a pair of coregulated exons: promotes inclusion of the smooth muscle (SM) exon bu [...] | RALYL isoform 7. | 0.712 |
| CELF1 | ENSPPYP00000001461 | ENSPPYP00000003787 | ENSPPYP00000001461 | CUGBP Elav-like family member 1; RNA-binding protein implicated in the regulation of several post-transcriptional events. Involved in pre-mRNA alternative splicing, mRNA translation and stability. Mediates exon inclusion and/or exclusion in pre-mRNA that are subject to tissue-specific and developmentally regulated alternative splicing. Specifically activates exon 5 inclusion of cardiac isoforms of TNNT2 during heart remodeling at the juvenile to adult transition. Acts as both an activator and repressor of a pair of coregulated exons: promotes inclusion of the smooth muscle (SM) exon bu [...] | annotation not available | 0.811 |
| CELF1 | ENSPPYP00000019655 | ENSPPYP00000003787 | ENSPPYP00000019655 | CUGBP Elav-like family member 1; RNA-binding protein implicated in the regulation of several post-transcriptional events. Involved in pre-mRNA alternative splicing, mRNA translation and stability. Mediates exon inclusion and/or exclusion in pre-mRNA that are subject to tissue-specific and developmentally regulated alternative splicing. Specifically activates exon 5 inclusion of cardiac isoforms of TNNT2 during heart remodeling at the juvenile to adult transition. Acts as both an activator and repressor of a pair of coregulated exons: promotes inclusion of the smooth muscle (SM) exon bu [...] | annotation not available | 0.811 |
| CELF1 | HNRNPC | ENSPPYP00000003787 | ENSPPYP00000006361 | CUGBP Elav-like family member 1; RNA-binding protein implicated in the regulation of several post-transcriptional events. Involved in pre-mRNA alternative splicing, mRNA translation and stability. Mediates exon inclusion and/or exclusion in pre-mRNA that are subject to tissue-specific and developmentally regulated alternative splicing. Specifically activates exon 5 inclusion of cardiac isoforms of TNNT2 during heart remodeling at the juvenile to adult transition. Acts as both an activator and repressor of a pair of coregulated exons: promotes inclusion of the smooth muscle (SM) exon bu [...] | Heterogeneous nuclear ribonucleoprotein C; Binds pre-mRNA and nucleates the assembly of 40S hnRNP particles. Interacts with poly-U tracts in the 3'-UTR or 5'-UTR of mRNA and modulates the stability and the level of translation of bound mRNA molecules. Single HNRNPC tetramers bind 230-240 nucleotides. Trimers of HNRNPC tetramers bind 700 nucleotides. May play a role in the early steps of spliceosome assembly and pre-mRNA splicing. N6-methyladenosine (m6A) has been shown to alter the local structure in mRNAs and long non-coding RNAs (lncRNAs) via a mechanism named 'm(6)A-switch', facilit [...] | 0.950 |
| CELF1 | RALY | ENSPPYP00000003787 | ENSPPYP00000024392 | CUGBP Elav-like family member 1; RNA-binding protein implicated in the regulation of several post-transcriptional events. Involved in pre-mRNA alternative splicing, mRNA translation and stability. Mediates exon inclusion and/or exclusion in pre-mRNA that are subject to tissue-specific and developmentally regulated alternative splicing. Specifically activates exon 5 inclusion of cardiac isoforms of TNNT2 during heart remodeling at the juvenile to adult transition. Acts as both an activator and repressor of a pair of coregulated exons: promotes inclusion of the smooth muscle (SM) exon bu [...] | RALY heterogeneous nuclear ribonucleoprotein. | 0.922 |
| CR201_G0050254 | AADAT | ENSPPYP00000020986 | ENSPPYP00000016979 | RALYL isoform 7. | Aminoadipate aminotransferase. | 0.714 |
| CR201_G0050254 | CELF1 | ENSPPYP00000020986 | ENSPPYP00000003787 | RALYL isoform 7. | CUGBP Elav-like family member 1; RNA-binding protein implicated in the regulation of several post-transcriptional events. Involved in pre-mRNA alternative splicing, mRNA translation and stability. Mediates exon inclusion and/or exclusion in pre-mRNA that are subject to tissue-specific and developmentally regulated alternative splicing. Specifically activates exon 5 inclusion of cardiac isoforms of TNNT2 during heart remodeling at the juvenile to adult transition. Acts as both an activator and repressor of a pair of coregulated exons: promotes inclusion of the smooth muscle (SM) exon bu [...] | 0.712 |
| CR201_G0050254 | ENSPPYP00000001461 | ENSPPYP00000020986 | ENSPPYP00000001461 | RALYL isoform 7. | annotation not available | 0.787 |
| CR201_G0050254 | ENSPPYP00000019655 | ENSPPYP00000020986 | ENSPPYP00000019655 | RALYL isoform 7. | annotation not available | 0.787 |
| CR201_G0050254 | HNRNPC | ENSPPYP00000020986 | ENSPPYP00000006361 | RALYL isoform 7. | Heterogeneous nuclear ribonucleoprotein C; Binds pre-mRNA and nucleates the assembly of 40S hnRNP particles. Interacts with poly-U tracts in the 3'-UTR or 5'-UTR of mRNA and modulates the stability and the level of translation of bound mRNA molecules. Single HNRNPC tetramers bind 230-240 nucleotides. Trimers of HNRNPC tetramers bind 700 nucleotides. May play a role in the early steps of spliceosome assembly and pre-mRNA splicing. N6-methyladenosine (m6A) has been shown to alter the local structure in mRNAs and long non-coding RNAs (lncRNAs) via a mechanism named 'm(6)A-switch', facilit [...] | 0.931 |
| CR201_G0050254 | PPIE | ENSPPYP00000020986 | ENSPPYP00000001735 | RALYL isoform 7. | Peptidyl-prolyl cis-trans isomerase E; Involved in pre-mRNA splicing as component of the spliceosome. Combines RNA-binding and PPIase activities. Binds mRNA and has a preference for single-stranded RNA molecules with poly-A and poly-U stretches, suggesting it binds to the poly(A)-region in the 3'- UTR of mRNA molecules. Catalyzes the cis-trans isomerization of proline imidic peptide bonds in proteins. Inhibits KMT2A activity; this requires proline isomerase activity. | 0.745 |
| CR201_G0050254 | RALY | ENSPPYP00000020986 | ENSPPYP00000024392 | RALYL isoform 7. | RALY heterogeneous nuclear ribonucleoprotein. | 0.915 |
| CR201_G0050254 | RBM22 | ENSPPYP00000020986 | ENSPPYP00000017855 | RALYL isoform 7. | Pre-mRNA-splicing factor RBM22; Required for pre-mRNA splicing as component of the activated spliceosome. Involved in the first step of pre-mRNA splicing. Binds directly to the internal stem-loop (ISL) domain of the U6 snRNA and to the pre-mRNA intron near the 5' splice site during the activation and catalytic phases of the spliceosome cycle. Involved in both translocations of the nuclear SLU7 to the cytoplasm and the cytosolic calcium-binding protein PDCD6 to the nucleus upon cellular stress responses; Belongs to the SLT11 family. | 0.734 |
| CR201_G0050254 | SKA2 | ENSPPYP00000020986 | ENSPPYP00000009894 | RALYL isoform 7. | Spindle and kinetochore associated complex subunit 2. | 0.699 |
| CR201_G0050254 | YBX1 | ENSPPYP00000020986 | ENSPPYP00000001698 | RALYL isoform 7. | YBX1 isoform 1. | 0.731 |
| ENSPPYP00000001461 | CELF1 | ENSPPYP00000001461 | ENSPPYP00000003787 | annotation not available | CUGBP Elav-like family member 1; RNA-binding protein implicated in the regulation of several post-transcriptional events. Involved in pre-mRNA alternative splicing, mRNA translation and stability. Mediates exon inclusion and/or exclusion in pre-mRNA that are subject to tissue-specific and developmentally regulated alternative splicing. Specifically activates exon 5 inclusion of cardiac isoforms of TNNT2 during heart remodeling at the juvenile to adult transition. Acts as both an activator and repressor of a pair of coregulated exons: promotes inclusion of the smooth muscle (SM) exon bu [...] | 0.811 |
| ENSPPYP00000001461 | CR201_G0050254 | ENSPPYP00000001461 | ENSPPYP00000020986 | annotation not available | RALYL isoform 7. | 0.787 |
| ENSPPYP00000001461 | RALY | ENSPPYP00000001461 | ENSPPYP00000024392 | annotation not available | RALY heterogeneous nuclear ribonucleoprotein. | 0.843 |
